Image5_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG by Hamza Kamran (18433152)

“…The 14–22 amide (myr) PKA inhibitor alone elicits ER Ca²⁺ release, and subsequent treatment with D,L-methadone does not cause additional ER Ca²⁺ release, indicating that PKA inhibition is a key step in D,L-methadone-induced ER Ca²⁺ release and can bypass the D,L-methadone-OPRM1-AC-cAMP step. …”

The GTPase RalA Regulates Different Steps of the Secretory Process in Pancreatic β-Cells by Sanda Ljubicic (257524)

“…Silencing of this GTPase in INS-1E cells by RNA interference led to a decrease in secretagogue-induced insulin release. …”

Stepwise addition of DMSO. by Renquan Ruan (721497)

Conceptual diagram summarising the three main steps of the analyses. by Nina McLean (4872268)

Lentivirus-mediated FGFR1 overexpression in A549 cells significantly decreased influenza A virus replication. by Xin Liu (43569)

Lead Exposure Inhibits Fracture Healing and Is Associated with Increased Chondrogenesis, Delay in Cartilage Mineralization, and a Decrease in Osteoprogenitor Frequency-5 by Jonathan J. Carmouche (71816)

A decreased yield of RNP1, RNP2 and RNP5 formation in the presence of protein aGAR1 is counteracted by RNA-S by Bruno Charpentier (9519)

A Bcl-2-BH4 double-glycine variant (I14G/V15G) has a decreased by Giovanni Monaco (452223)

Fig 5 - by Dennis Ochola (11626912)

Comparing the flow distribution within A-V and V-A-V structures derived from the same vascular bed. by Fatemeh Mirzapour-Shafiyi (10981427)

Microstructure Evolution of the Mg-5.8 Zn-0.5 Zr-1.0 Yb Alloy During Homogenization by Lu Li (14069)

“…After homogenization, most of the eutectic phases dissolve into the matrix, except for a small amount of Mg-Zn-Yb phase. The area fractions of residual secondary phase decrease from 5.54% in the as-cast alloy to 0.59% in the well-homogenized sample. …”

PPP2R5C HepKD in <i>db/db</i> mouse liver improves insulin sensitivity, decreases hyperglycemia, but worsens the dyslipidemia. by Yong-Sheng Cheng (803758)

“…<p><b>(A)</b> Hyperglycemia in <i>db/db</i> mice is decreased upon hypatocyte-specific PPP2R5C knockdown with adeno-associated virus. …”

Changes in the color parameters of cherry shrimp (<i>N</i>. <i>davidi</i> var. red) in different feed treatment groups^a over a 56-day period (mean ± SD, <i>n</i> = 20). by Wei-Wei Hou (3405947)

Subjects:

Reduction of Acc1 protein level decreases glucose-deprived stress granule formation. by Meaghen Rollins (3776008)

Interaction of Biotin with Mg−O Bonds:  Bifunctional Binding and Recognition of Biotin and Related Ligands by the Mg(15-crown-5)²⁺ Unit by Elizabeth R. Sanchez (2987076)

“…This can be understood in terms of the structure of Mg(15-crown-5)(Otf)₂. It shows a pentagonal bipyramidal coordination geometry where the five equatorial positions are occupied by the macrocyclic oxygen donors. …”

Liquid–Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media by Qingwen Bai (5221280)

“…Our study provides a further step toward a deeper understanding of the kinetics of MLOs in crowded living cells.…”

Liquid–Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media by Qingwen Bai (5221280)

“…Our study provides a further step toward a deeper understanding of the kinetics of MLOs in crowded living cells.…”

Liquid–Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media by Qingwen Bai (5221280)

“…Our study provides a further step toward a deeper understanding of the kinetics of MLOs in crowded living cells.…”

Effect of Safr and Cands on the levels of 5-hydroxytryptamine (5-HT, μg/g tissue), 5-hydroxyindoleacetic acid (5-HIAA, μg/g tissue), norepinephrine (NE, μg/g tissue) and dopamine (... by Nagwa Ibrahim Shehata (17319689)

The T37A substitution increases both H5N6 M1 protein stability and H5N6 viral replication in mammals. by Chenxi Wang (284364)

Subjects: