Differentially regulated genes reside in closed chromatin regions and undergo dynamic changes in chromatin signature during fate transitions. by Ao Liu (481251)

“…Open regions are dark purple; closed regions are white. <b>(B)</b> Example of a shared bHLH target (SWEET5) that is nucleosome bound (MNase-seq [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002770#pbio.3002770.ref038" target="_blank">38</a>]; top track, deep blue), heavily H3K27me3-methylated in early stomatal lineage cells (H3K27me3 ChIP-seq in FAMA^LGK cells [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002770#pbio.3002770.ref037" target="_blank">37</a>]; second track, light blue) and shows a decrease in H3K27me3 in mature GCs (H3K27me3 ChIP-seq in GC [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002770#pbio.3002770.ref037" target="_blank">37</a>]; third track, green); the bottom 5 tracks show binding of the stomatal lineage bHLHs and the chromatin remodeler BRM from ChIP-seq experiments. …”

ORC2 silencing enhanced PV replication in proliferating and differentiating CIN612-9E cells. by Marsha DeSmet (2513767)

“…<p>(A) ORC2 siRNA duplexes decreased ORC2 protein levels at a concentration of 15 or 5 nM after 48 h. …”

<i>col-Tv</i> enhancer analysis. by Johannes Stratmann (2697598)

“…(M) Quantification of the β-gal levels in the NB5-6 shows that all <i>col-Tv-CRM</i> fragments with mutated binding sites for <i>col</i> upstream activators, show a significant decrease in activity compared to control levels. …”

Characteristics and findings of all studies included (n = 72). by Isabella Eckerle (381546)

“…</p>21<p>mean response after PCV7 only to serotypes 4, 6B, 9V, 14, 18C, 19F, 23F.…”

Loss of <i>Lhx6</i> compromises dental mesenchymal proliferation in the furcation development region. by Jinzhi He (10156964)

“…<p>(A-B) Ki67 staining of FDR from control and <i>Lhx6</i>^<i>-/-</i> mice at PN7.5. …”

Complete Suppression of Blinking and Reduced Photobleaching in Single MEH-PPV Chains in Solution by Suguru Onda (1281132)

“…Adsorption of the chains onto a substrate in the solution leads to 34% decrease in fluorescence intensity (quantum efficiency), five-fold increase in the rate of photobleaching and appearance of blinking. …”

Chromosomal integration of HPV16 genomes causes host transcript modulation through host:host interaction changes within TADs. by Ian J. Groves (8703930)

“…<p>(A) Comparative analysis of Hi-C libraries between clones G2 and D2 shows significant differentially interacting regions (DIRs) within the TAD of integration (red–increased host:host interactions in clone G2 vs D2; blue–decreased host:host interactions in clone G2 vs D2), including the decreased interaction in clone G2 between the <i>ARL15</i> locus/TAD boundary (Chr5: 53.52Mbp, turquoise arrowhead) and the locus between <i>MOCS2</i> and <i>FST</i> (Chr5: 52.4Mbp, orange arrowhead), highlighted as a ‘yellow outlined triangle’. …”

U-PB zircon tuff geochronology from the Karoo Basin, South Africa: implications of zircon recycling on stratigraphic age controls by Matthew P. McKay (692203)

Supplementary Material for: Deoxycytidine Kinase (<b><i>DCK</i></b>) Mutations in Human Acute Myeloid Leukemia Resistant to Cytarabine by Wu B. (3665515)

“…Deoxycytidine kinase, encoded by <i>DCK</i>, catalyzes phosphorylation of cytarabine to cytarabine monophosphate, a necessary step for eventual incorporation of cytarabine triphosphate into DNA and for clinical efficacy. …”

Supplementary Material for: Evolution of growth following anti-TNF-α therapy in paediatric Crohn’s disease: data from the Swiss IBD Cohort Study by figshare admin karger (2628495)

“…Height velocity z-scores showed a significant increase across both genders. Factors contributing to a decreased height z-score included male sex, age 10 and below at diagnosis, a concomitant corticosteroid treatment and a top-down treatment strategy. …”

Expert consensus definition of treatment intolerance in chronic myeloid leukemia in chronic phase by Ehab Atallah (17664292)

“…This definition represents a step forward in standardizing care for patients with CML-CP by presenting a balanced framework for managing TKI therapy, which will support shared decision-making.…”

Increased decision thresholds in patients with OCD. by Tobias U. Hauser (705683)

“…The increasing errorbars in the decreasing condition at later stages shows that even simulated agents rarely sample beyond the 15th step in this condition.…”

Smo ubiquitination is regulated by Hh and phosphorylation. by Ruohan Xia (188658)

“…<p>(A) S2 cells were transfected with Myc-Smo and treated with 30% (lanes 2 and 5) or 60% (lanes 3 and 6) of Hh-conditioned medium or control medium (lanes 1 and 4), followed by treatment with or without NH₄Cl. …”

BODIPY-cholesterol efflux from fibroblasts is affected by ShhN. by Michel Bidet (206600)

“…<p>BODIPY-cholesterol induces the accumulation of Smo in the plasma membrane as cholesterol (A). Plasma membrane enriched fractions from control NIH 3T3 (A, lane 1), NIH 3T3 treated for 6 h with 30 nM ShhN (A, lane 2), and NIH 3T3 treated for 3 h with 2.5 µM BODIPY-cholesterol (A, lane 3) were prepared for immunoblotting with antibodies against Smo. …”

The Effects of Licorice (Glycyrrhriza glabra) Root on Performance, Some Serum Parameters and Antioxidant Capacity of Laying Hens by S Canogullari Dogan (6099458)

“…From the experimental findings, it was ascertained that the licorice root supplementation had no significant effect on egg weight and feed conversion ratio (p>0.05), but feed consumption decreased with increasing licorice root (p<0.05).Egg yield was recorded as 88.94%, 89.56%, 86.82% and 85.02% in the groups of 0, 0.5, 1.0 and 2.0, respectively (p<0.05).Plasma low density lipoprotein (LDL) and egg yolk cholesterol level decreased with the addition of licorice root, while plasma high density lipoprotein (HDL) level was increased with licorice root addition (p<0.05). …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…In contrast, we observed decreases of the ratio after exposure to PM_2.5 and PM₁₀. …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…In contrast, we observed decreases of the ratio after exposure to PM_2.5 and PM₁₀. …”

Initial 2022 projections of the west coast rock lobster resource. by Susan Holloway (9998819)

“…<p>This document presents estimated biomass trajectories for a range of future catch scenarios. Results are computed using the recent 2022 updated stock assessments for each of the five Super-areas. …”

Desflurane increases intrinsic excitability of granule cells. by Jonathan Mapelli (416983)

“…Note the decreased number of current steps required to generate action potentials and the increased number of elicited spikes, concomitant with a reduced firing threshold (arrow). …”

Is virtual reality useful for pain management in patients who undergo medical procedures? by Daniel Melecchi de Oliveira Freitas (6720089)