The cHS4 insulator block activation of Map17 but not Tal1. by Romain Desprat (73077)

“…<p>A: PCR analysis demonstrating insertion of 5 cassettes at RL5 in each orientation (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005956#s4" target="_blank">methods</a>). …”

MEK1 interaction with PPARα induces nuclear export. by Hamid el Azzouzi (318740)

“…<p>(a) Western blot analysis on precipitates of HEK293 cells transiently co-transfected with PPARα-V5, MEK1 and treated with U0126 (5 µM) or not for 2 hr and immunoprecipitated using an anti-MEK1 antibody. …”

Survival and diapause induction. by Mariana Abarca (6792434)

“…<p>A) Probability of survival and B) diapause induction (LS means ± SE) of individuals kept at each of three oscillating temperature regimes (mean ± 5), feeding on either a high quality (green, open circles, kudzu, <i>Pueraria montana</i>) or a low quality (yellow, solid circles, wisteria, <i>Wisteria sinensis</i>) host. …”

Datasheet1_MRI visibility and displacement of elective lymph nodes during radiotherapy in head and neck cancer patients.pdf by Floris C. J. Reinders (14049621)

EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer - Fig 9 by Stephanie Rossnagl (553093)

“…<p><b>Myeloid cells are intrinsically different based on exposure to EDA-FN.</b> (A) Adoptive transfer using similar numbers of isolated CD11b⁺-cells from cKO and CT animals mixed with B16 melanoma cells and injected subcutaneously showed a significant decrease in growth in the tumors that contained cKO CD11b⁺-cells, <i>n</i> = 16/10/18/18. …”

Data_Sheet_1_Whole Body Vibration Improves Spatial Memory, Anxiety-Like Behavior, and Motor Performance in Aged Male and Female Rats.pdf by Tamás Oroszi (11983592)

“…WBV-treated rats showed a decrease in their anxiety level in the open field test compared with those in the pseudo-treated controls. …”

Transcriptomics insight into occupational exposure to engineered nanoparticles by Zuzana Simova (19368296)

“…</p> <p>Following PM0.1 exposure, a significant decrease in the expression of <i>DDIT4</i> and <i>FKBP5</i>, genes involved in the stress response, was detected in exposed workers. …”

Glomerular-specific innervation pattern of the CSDn in the AL is regulated by Ephrin. by Ajeet Pratap Singh (404076)

“…(B-B″, F) In <i>Ephrin^KG09118</i> hypomorphs, increased terminal innervations can be seen to VA1l/m (n = 5, p<0.001), DA1 (n = 5, p<0.001) and DL3 (n = 9, p = 0.018) while innervations in VA1d (n = 5, p = 0.865) and V (n = 4, p = 0.149) are comparable to controls. …”

Chromatin conformation and bound CTCF sites at the mouse and chick <i>HoxD</i> locus. by Nayuta Yakushiji-Kaminatsui (6008795)

“…(E, F) Subtraction of the CHi-C matrices shown in (B) between the <i>HoxD</i> cluster and the area from region a to region b within T-DOM at a 5-kb resolution. …”

Role of MSLN in cellular growth, cell cycle progression and apoptosis, following treatment with chemotherapeutic drugs. by Ombretta Melaiu (511640)

“…<p><i>A</i>. Proliferation assay in Mero-14 cells. The graph shows the effect of the treatments with 5 µM cisplatin and 40 nM siMSLN-1, used as single agents or in combination. …”

Role of Duplicate Genes in Robustness against Deleterious Human Mutations by Tzu-Lin Hsiao (42604)

“…The contribution of close sequence homologs to genetic robustness against null mutations has been previously demonstrated in simple organisms <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000014#pgen.1000014-Gu1">[4]</a>,<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000014#pgen.1000014-Conant1">[5]</a>. …”

Summary of the TAFV challenge study results through 15 days post challenge (study day 70–85). by Kelly L. Warfield (130405)

“…<i>0°F over baseline; Temp drop was defined as a temperature more than 3</i>.<i>0°F below baseline; mild rash = focal areas of petechiae covering less than 10% of skin; moderate rash = areas of petechiae covering between 10% and 40% of the skin; severe rash = areas of petechiae or ecchymosis covering more than 40% of the skin</i></p><p><i>↑</i>, <i>2- to 3-fold increase</i></p><p><i>↑↑</i>, <i>4- to 5-fold increase</i></p><p><i>↑↑↑</i>, <i>> 5-fold increase</i></p><p><i>↓</i>, <i>2- to 3-fold decrease</i></p><p><i>WL</i>: <i>weight loss was the percentage compared to the weight at study initiation; BUN</i>: <i>blood urea nitrogen; ALT</i>: <i>alanine aminotransferase; AST</i>: <i>aspartate aminotransferase; ALP</i>: <i>alkaline phosphatase; ALB</i>: <i>albumin</i>, <i>Glu</i>: <i>glucose</i>, <i>Cre</i>: <i>creatinine</i>, <i>WBC</i>: <i>white blood cells; Plt</i>: <i>platelet</i>, <i>Lym</i>: <i>lymphocyte</i>.…”

Table_1_Multimodal evaluation of the bloodstream alteration before and after combined revascularization for Moyamoya disease.DOCX by Lei Cao (134409)

“…The analysis of FLOW800 indicated that both the delay time and rise time experienced a substantial decrease in both the recipient artery and vein. …”

Data_Sheet_1_Hemodynamic effects and tolerance of dobutamine for myocardial dysfunction during septic shock: An observational multicenter prospective echocardiographic study.docx by Keyvan Razazi (4094935)

“…Dobutamine was discontinued for poor tolerance in a majority of patients (n = 21, 66%) at any dose and half of patients (n = 15, 47%) at low-dose (5 μg/kg/min). …”

Azocyclotin Binds CDK4 to Disrupt DNA Methylation in Zebrafish Epigenetic Transgenerational Inheritance by Aoxue Wang (275954)

“…Using zebrafish ZF4 cells as an <i>in vitro</i> model, we elucidated the mechanism by which ACT modulates DNA methylation. ACT exposure induced a 38.03% decrease in global DNA methylation, as determined by 5-mC quantification. …”

Image_2_Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea.jpeg by Andrea Pagano (7845914)

“…</p>Results and discussion<p>After 3 weeks of recovery from zebularine treatment, a decrease of 5-mC levels was observed in different genomic contexts in the roots of explants that were exposed to zebularine, whereas a functionally heterogeneous subset of protein entries was differentially accumulated in stem samples, including entries related to cell wall biosynthesis, tissue morphogenesis, and hormonal regulation. …”

Table_3_Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea.xlsx by Andrea Pagano (7845914)

“…</p>Results and discussion<p>After 3 weeks of recovery from zebularine treatment, a decrease of 5-mC levels was observed in different genomic contexts in the roots of explants that were exposed to zebularine, whereas a functionally heterogeneous subset of protein entries was differentially accumulated in stem samples, including entries related to cell wall biosynthesis, tissue morphogenesis, and hormonal regulation. …”

Azocyclotin Binds CDK4 to Disrupt DNA Methylation in Zebrafish Epigenetic Transgenerational Inheritance by Aoxue Wang (275954)

“…Using zebrafish ZF4 cells as an <i>in vitro</i> model, we elucidated the mechanism by which ACT modulates DNA methylation. ACT exposure induced a 38.03% decrease in global DNA methylation, as determined by 5-mC quantification. …”

Image_1_Declines and Resilience of Communities of Leaf Chewing Insects on Missouri Oaks Following Spring Frost and Summer Drought.JPEG by Robert J. Marquis (2903021)

“…We present evidence that mid spring frosts and summer drought negatively affect the community of insects found on Missouri oaks (Quercus alba and Q. velutina), amounting to a 23–186 fold decrease depending on the oak species, insect body size and feeding guild, and the specific weather event. …”

Image_8_Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea.png by Andrea Pagano (7845914)

“…</p>Results and discussion<p>After 3 weeks of recovery from zebularine treatment, a decrease of 5-mC levels was observed in different genomic contexts in the roots of explants that were exposed to zebularine, whereas a functionally heterogeneous subset of protein entries was differentially accumulated in stem samples, including entries related to cell wall biosynthesis, tissue morphogenesis, and hormonal regulation. …”