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13921
Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects
Published 2012“…Consistent with its role limiting fatty acid biosynthesis, both <em>BrCa1</em> mRNA (3.5-fold, p<0.0001) and protein (1.2-fold, p = 0.001) were increased in pre-adipocytes, and decreased during <em>in vitro</em> adipogenesis, while P-ACC decreased during differentiation of human adipocytes (p = 0.005) allowing lipid biosynthesis. …”
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13922
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13923
A Role for <i>Smoothened</i> during Murine Lens and Cornea Development
Published 2014“…Mutant lenses were smaller and showed normal expression of p57Kip2, c-Maf, E-cadherin and Pax6, reduced expression of FoxE3 and Ptch1 and decreased nuclear Hes1. There was normal G1-S phase but decreased G2-M phase transition at E16.5 and epithelial cell death from E14.5-E16.5. …”
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13924
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13925
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13926
Knockdown of UAP56 impairs A/chicken/Malaysia/5858/2004 H5N1 virus growth.
Published 2013“…Fourty-eight hours later, depleted cells were infected with A/chicken/Malaysia/5858/2004 H5N1 at MOI of 5. …”
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13927
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13928
Nonlatching positive feedback substantially dampens the Poissonian noise-mean inverse relationship, allowing stochastic extinction despite increasing mean-expression levels.
Published 2017“…<p>(A) In the classical Poisson or super-Poissonian transcriptional burst models [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2000841#pbio.2000841.ref050" target="_blank">50</a>], the expression mean scales with variance (σ<sup>2</sup> ∝ μ) such that the noise magnitude (CV<sup>2</sup> = σ<sup>2</sup> / μ<sup>2</sup>) decreases proportionally to the inverse of the mean. …”
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13929
Characterization of CFDP1-H2A.Z interaction.
Published 2024“…(E) CFDP1 depletion led to a remarkable reduction in chromatin incorporation of exogenously supplied FLAG-H2A.Z compared to control siRNA (con si)-treated cells (<2.5-fold). …”
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13930
Degradation of GKAP after Aβ treatment is mediated by cdk-5-dependent phosphorylation of two epitopes at S77 and S111.
Published 2011“…<p>(<i>A</i>) GKAP and cdk5 colocalize in synaptic sites. …”
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13931
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13932
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13933
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13934
DataSheet_4_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”
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13935
DataSheet_3_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”
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13936
DataSheet_6_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”
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13937
DataSheet_1_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”
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13938
DataSheet_2_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”
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13939
DataSheet_7_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”
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13940
DataSheet1_The effect of a traditional Chinese quadri-combination therapy and its component quercetin on recurrent spontaneous abortion: A clinical trial, network pharmacology and...
Published 2022“…The protective effect of quercetin on trophoblasts, through decreasing Drp1 expression via regulating miR-34a-5p, might be one possible effective mechanism.…”