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13041
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13042
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13043
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13044
T-maze performance is associated with dynamic, speed-independent regulation of hippocampal theta frequency at the choice point.
Published 2016“…(E) As the rats navigated down the maze, running speed followed a predictable pattern (increasing in the central arm, decreasing at the choice point, and increasing again in the end arm). …”
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13045
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13046
Image_5_Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson’s Disease.TIF
Published 2018“…In another set of experiments with SH-SY5Y dopaminergic cells, orexin-A significantly induced the expression of BDNF in a dose and time-dependent manner. …”
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13047
Association of Matrix Metalloproteinase-3 -1171(5A>6A) Polymorphism with Cancer Risk: A Meta-Analysis of 41 Studies
Published 2014“…It was noteworthy that we had a contrary finding in non-smokers: the variant 6A/6A homozygote might statistically increase cancer risk compared with 6A/5A+5A/5A genotype (OR = 1.92, 95%CI: 1.25—2.96; I<sup>2</sup> = 72.7%).…”
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13048
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13049
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13050
Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner
Published 2018“…We previously demonstrated that mitochondrial targeting of small RNAs designed to anneal with mutant mtDNA can decrease the heteroplasmy level by specific inhibition of mutant mtDNA replication, thus representing a potential therapy. …”
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13051
Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis
Published 2018“…In ROM analysis, PV showed no significant increase in the placebo group, with a ROM of 1.00 (95% CI, 0.88, 1.14). The 5ARI treatment resulted in a significantly higher incidence of decreased libido (OR = 1.7; 95% CI, 1.36, 2.13), ejaculatory disorder (OR = 2.94; 95% CI, 2.15, 4.03), gynecomastia (OR = 2.32; 95% CI, 1.41, 3.83), and impotence (OR = 1.74; 95% CI, 1.32, 2.29). …”
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13052
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13053
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13054
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13055
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13056
Atg14 plays a cell-intrinsic role in orchestrating eTreg survival but not terminal differentiation.
Published 2025“…PSEA of differentially accessible peaks in eTregs (|log<sub>2</sub>FC | > 0.5, <i>P</i> < 0.05) derived from the spleen of <i>Foxp3</i><sup>Cre</sup><i>Atg14</i><sup>fl/fl</sup> mixed BM chimera mice versus control counterparts, using public gene signatures [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.ref011" target="_blank">11</a>] of the indicated Treg populations (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#sec010" target="_blank">Materials and methods</a> for details) (<b>F</b>). …”
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13057
Table_1_NBCe2 (Slc4a5) Is Expressed in the Renal Connecting Tubules and Cortical Collecting Ducts and Mediates Base Extrusion.DOCX
Published 2020“…In isolated renal CNT and CCD, genetic deletion of NBCe2 leads to decreased net base extrusion. To determine the role of renal NBCe2 in the development of hypertension, we generated CNT and intercalated cell NBCe2 knockout mice by crossing an Slc4a5 lox mouse with mice expressing cre recombinase under the V-ATPase B1 subunit promotor. …”
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13058
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13059
Palladium-Catalyzed Asymmetric Intramolecular Dearomative Heck Annulation of Aryl Halides to Furnish Indolines
Published 2021“…An unprecedented Pd-catalyzed asymmetric intramolecular cascade cyclization of aryl halides with readily available arylboronic acids proceeds through a Heck-type dearomative cyclization terminated with arylation in the presence of Pd<sub>2</sub>(dba)<sub>3</sub> (10 mol %), Cu<sub>2</sub>O (5 mol %), and Cs<sub>2</sub>CO<sub>3</sub> (2.0 equiv) in 1,2-dichloroethane (1.0 mL) at 100 °C for 15 h in air using BINOL-based phosphoramidite as the chiral ligand. …”
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13060
Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway
Published 2025“…</p> <p>PCG demonstrated an anti-inflammatory effect in LPS-induced DPCs by targeting the NF-κB/Wnt5a-ROR2 signaling pathway.</p> <p></p> <p>This schematic illustration demonstrates that PCG ameliorates LPS-elicited pulpitis by decreasing the expression of the proteins associated with the NF-κB signaling pathway and its downstream Wnt5a/ROR2 pathway and by reducing the production of inflammatory molecules.…”