Replacing i3 of Rs1 with that of 5-HT_1A results in a receptor, Rs1-i3-5-HT_1A, with weak G_isignaling. by Wei Chun Chang (43479)

“…<p>(A) Rs1-i3-5-HT_1A chimera decreased cAMP accumulation. …”

Respiratory network responses to systemic 5-HT_2AR and 5-HT_2BR activation. by Marcus Niebert (183419)

“…Statistical analysis (paired t-test) is denoted in the panels on the right side. (<b>A</b>–<b>C</b>) Action of 5-HT_2AR and 5-HT_2BR ligands in the perfused brainstem preparation. …”

SUNBURN PROTECTANT DECREASES THE INCIDENCE OF BULL'S EYE AND WHITE ROTS IN ‘FUJI STANDARD’ AND ‘PINK LADY’ APPLES by ROSA MARIA VALDEBENITO-SANHUEZA (12701675)

Overexpression of Gβγ subunits results in decreased DAT uptake activity in HEK-293-DAT cells. by Jennie Garcia-Olivares (394634)

“…(<b>C</b>) Overexpression of Gβ4 (n = 5) or Gβ5 (n = 7) (gray bars), decreased [³H]-DA uptake in HEK293-DAT cells when compared to control (white bar, n = 19). …”

The top 28 metabolites whose concentrations were statistically elevated or decreased in HIV patients compared to controls. by Bruno Scarpelini (3394346)

Deletion of both Nesprin 1 and 2 causes decreased cardiac wall thickness and impaired cardiac function. by Indroneal Banerjee (525222)

PRRSV enters MARC-145 cells via macropinocytosis and rottlerin blocks the macropinocytosis by decreasing actin polymerization. by Yeonglim Kang (21395261)

Acute GM exposure decreased NADH Fl in basal turn OHCs bathed in T1 imaging buffer. by Heather C. Jensen-Smith (319902)

“…B) Although basal turn, high-frequency IHCs were unaltered by GM, basal turn OHCs displayed a significant decrease in NADH Fl within 10 min of GM exposure (t(7) = 2.0, p<0.05, n_GM = 5, n_Cont = 4). …”

The influence of leucettines as DYRK1A inhibitors on insulin, C-peptide, and glucagon production by MIN6 cells. by Barbara Pucelik (2988795)

CX3CR1-/- primary microglia show decreased antigen processing in <i>in vitro</i>. by Aaron D. Thome (813759)

“…<p>(A) Antigen processing of DQ Ovalbumin (red) is decreased in CX3CR1-/- primary microglia compared to WT primary microglia following a 30 minute treatment. …”

SFN decreases immunosuppressive MDSC formation in response to GCM but increases CD14-/HLA-DR+ cells. by Ravi Kumar (188257)

“…Addition of SFN is associated with a dose-dendent reduction in mMDSC’s (5uM SFN = 42.5% mMDSC’s; 10uM SFN = 5.2% mMDSC’s) (bottom left and right; percent shown in red). …”

Image_1_Neuroplastin 65 deficiency reduces amyloid plaque formation and cognitive deficits in an Alzheimer’s disease mouse model.TIF by Dan-Dan Wu (1449316)

“…Finally, protein levels of 5-hydroxytryptamin (serotonin) receptor 3A and synaptic proteins and neurons were measured.…”

Image_2_Neuroplastin 65 deficiency reduces amyloid plaque formation and cognitive deficits in an Alzheimer’s disease mouse model.TIF by Dan-Dan Wu (1449316)

“…Finally, protein levels of 5-hydroxytryptamin (serotonin) receptor 3A and synaptic proteins and neurons were measured.…”

The expression of <i>Wnt1</i> gene was decreased in <i>Bmpr</i> double knockout mutants. by Lihua Qin (494786)

Tacrolimus decreased SFRP2 induced nuclear NFATc3 in 2H11 endothelial cells. by Sharareh Siamakpour-Reihani (218652)

USP-18 overexpression in RAW264.7 cells decreases production of IL-27 and IL-10. by Miguel Pinilla-Vera (3150138)

“…Cell supernatants were assessed using ELISA showing (A) decrease in production of mouse IL-27 in USP-18-V5 transfected cells compared to empty vector in the presence of LPS and (B) decreased levels of mouse IL-10 in USP-18-V5 transfected cells after LPS stimulation. …”

Key safety measures including adverse events. by Anuja Dokras (8679261)

“…<div><p>Background</p><p>The risk-to-benefit ratio of using combined oral contraceptive pills (COCPs) and/or metformin for comprehensive management of polycystic ovary syndrome (PCOS) in women with obesity is unclear. As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.…”

Improving Accuracy and Transferability of Machine Learning Chemical Activation Energies by Adding Electronic Structure Information by Esteban Marques (14713002)

“…Although data for chemical reactions is becoming increasingly available, the key step of encoding the reaction as an efficient descriptor remains a big challenge. …”

Inhibition of the STAT3 pathway and its upstream signaling decreases citrate levels during VACV infection. by Anil Pant (10074299)

“…<p><b>(A)</b> Inhibition of the EGFR pathway decreases the citrate level in VACV-infected HFFs. …”

Fluoro-Gold uptake is abolished in control conditions, and is decreased when AMPA is applied in the presence of blockers of endocytosis. by Melanie Falgairolle (759132)