The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes by Marie Neergaard Harder (232759)

“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”

Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. by Kyle C. Kloepping (9928265)

“…<p>(A) A375 melanoma cells were treated with 0.5 μM, 1.0 μM, or 2.0 μM 5-, 10-, or 16-TPP for 1 h and analyzed for mitochondria membrane potential by the JC-1 method (* significant relative to control; p<0.05; n = 2 from 2 separate experiments; N = 4). …”

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Treatment by AG1024 induces unpairing of adult worms and decrease of egg laying in a dose and time-dependent manner. by Mathieu Vanderstraete (154327)

DataSheet2_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.pdf by Sunil Veeravalli (5074115)

“…<p>We previously showed that Fmo5^−/− mice exhibit a lean phenotype and slower metabolic ageing. …”

DataSheet1_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.PDF by Sunil Veeravalli (5074115)

“…<p>We previously showed that Fmo5^−/− mice exhibit a lean phenotype and slower metabolic ageing. …”

HDAC5 inhibitors reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

3D representation of MeV-ΔV infected cells realized with IMARIS 9.9.1. by Pierre Khalfi (7868252)

Data_Sheet_2_Mycovirus Fusarium oxysporum f. sp. dianthi Virus 1 Decreases the Colonizing Efficiency of Its Fungal Host.pdf by Almudena Torres-Trenas (6445943)

Data_Sheet_1_Mycovirus Fusarium oxysporum f. sp. dianthi Virus 1 Decreases the Colonizing Efficiency of Its Fungal Host.docx by Almudena Torres-Trenas (6445943)

VEGFR2/VEGF-A ligand binding decreased ranibizumab and aflibercept mediated CCL2, CCL5, and CX3CL1 mRNA and protein levels in HCAECs. by Clare Arnott (2557705)

MAF1 protein expression is significantly decreased in luminal, HER2-positive, and TNBC breast cancer subtypes. by Stephanie Cabarcas-Petroski (9631636)

Class-specific mean decrease in accuracy (MDA) for directed motion and normal-, anomalous- and confined-diffusion. by Thorsten Wagner (1320081)

Decrease in cell migration and adhesion of MCF10A cells after knockdown of <i>MYO1C</i>. by Kittichate Visuttijai (3204519)

“…A dose-dependent decrease in relative cell index response to MYO1C depletion was observed reaching to a significant value with concentrations of 5 and 10 nM of <i>MYO1C</i>-siRNA at 48 hours post-transfection compared to control cells (mock transfection). …”

Modeling the Shape and Stability of Co Nanoparticles as a Function of Size and Support Interactions through DFT Calculations and Monte Carlo Simulations by Enrico Sireci (12127349)

“…We report a marked increase in step and kink sites at the expense of terraces with increasing particle size, which we linked to the experimentally observed increase in turnover frequency (TOF). …”

There is a significant decrease in fibroblast, α-SMA, and Ly6C staining accompanied with a decrease in proliferation, and increase in cell death in the outflow vein removed <i>Iex-... by Akshaar Brahmbhatt (551498)

“…</b> Pooled data from the semiquantitative analysis for intensity of Fsp-1 staining in the vessel wall of the outflow vein specimens removed from <i>Iex-1</i> KO and WT mice. There is a significant decrease in the mean Fsp-1 staining in the <i>Iex-1</i> KO animals when compared to WT controls (P<0.05). …”

A decrease in the invasiveness of <i>Candida albicans</i> into Caco-2 cells parallels the differentiation of intestinal epithelial cells. by Marianne Goyer (2550589)

“…The gene expression levels of Apolipoprotein A-IV (ΔΔCt) were statistically lower after 1, 2, 3 and 5 days post-seeding than at day 15 as a result of incomplete differentiation (*<i>p <</i> 0.05, Mann–Whitney test). …”

The Transition from a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk by Heba M Ismail (9568748)

“…Conclusions</p> <p>A transition from an increase to a decrease in AUC C-peptide approximately 1.5 years pre-diagnosis was validated in two independent cohorts. …”

Toca-1 recruitment around wild-type bacteria is associated with decreased recruitment of LC3 and autophagy markers. by Leigh A. Baxt (550378)

Fold decrease in virulence gene expression of <i>Salmonella in vivo</i> and <i>in vitro</i>^a. by Xiaojian Yang (295141)

“…Values represent down-regulation (fold-decrease) of gene expression.</p>#<p>Value for each gene represents a significant difference (<i>P</i><0.05) between the treatment and control samples in the <i>in vitro</i> experiment. …”