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64641
Rapid Changes in Serum Testosterone in Men with Newly Diagnosed Type 2 Diabetes With Intensive Insulin and Metformin
Published 2021“…<p>Methods: Seventy men with newly diagnosed drug naïve T2DM, HbA<sub>1c</sub> >9.0% (75mmol/mol) were treated with intensive insulin pump therapy for 5 days to achieve glucose normalization. …”
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64642
Effect of maternal BMI and maternal age on the fetal fraction.
Published 2024“…<p>(A) Decrease in fetal fraction with increasing maternal BMI (Pearson’s correlation coefficient = -0.36, p = 1.2e - 168). …”
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64643
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64644
Data_Sheet_2_Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.pd...
Published 2018“…</p><p>Results: The highest band intensities of EV markers Alix, Tsg101 and CD81 were detected by Western blot in F6 of small-scale DGUC (61.5 ± 10.4%; 48.1 ± 5.8%; 41.9 ± 3.8%, respectively) at a density of 1.128–1.174 g/mL, where the presence of vesicles with a mean diameter of 38 ± 2 nm was confirmed by EM and DLS. …”
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64645
Data_Sheet_1_Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.pd...
Published 2018“…</p><p>Results: The highest band intensities of EV markers Alix, Tsg101 and CD81 were detected by Western blot in F6 of small-scale DGUC (61.5 ± 10.4%; 48.1 ± 5.8%; 41.9 ± 3.8%, respectively) at a density of 1.128–1.174 g/mL, where the presence of vesicles with a mean diameter of 38 ± 2 nm was confirmed by EM and DLS. …”
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64646
Analyses of AtT-20 cell cycle by flow cytometry under lycopene (Lycop) or beta-carotene (beta-carot) stimulation.
Published 2013“…No significant differences between cell cycle phases were observed when AtT-20 cells were treated with 5 and 10 µM lycopene for 48 h (<b>A</b>), but after 96 h (<b>B</b>), cells in both concentrations showed an increase in G0/G1 and a decrease in S and G2/M phases. …”
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64647
Effect of CPP-ACP on enamel eroded extrinsically: in vitro study
Published 2018“…The paste in G4 did not promote an increase in hardness values nor a decrease in roughness values. Conclusion: It was concluded that CPP-ACP was unable to remineralize enamel subjected to extrinsic erosion, being ineffective in preventing erosion of enamel and in the remineralization of the eroded enamel.…”
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64648
Table_1_Ideal Cardiovascular Health in the Oldest-Old and Centenarians and Its Association With Disability and Health-Related Quality of Life.docx
Published 2021“…The EQ VAS and EQ-5D score show an increasing trend along with the increasing number of ICH indicators (p < 0.05). …”
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64649
Table1_Neuroprotective Effects of Oligosaccharides From Periplaneta Americana on Parkinson’s Disease Models In Vitro and In Vivo.DOCX
Published 2022“…The data demonstrated that OPA significantly reversed the MPP<sup>+</sup>-induced decrease in SH-SY5Y cell viability, reduced the proportion of apoptotic cells, and protected SH-SY5Y cells from apoptosis in a dose-dependent manner by regulating the expression of apoptosis-related genes. …”
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64650
Datasheet1_Trends in hypertension and hypertension treatment in primary care in general practices in Germany between 2013 and 2022.pdf
Published 2024“…After adjusting for covariates, there was a significant decrease in the number of patients diagnosed with hypertension (beta coefficient = −7.91, p-value < 0.001) and treated with any antihypertensive drug per practice per year between 2013 and 2022 (beta coefficient = −5.40, p-value < 0.001).…”
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64651
Synbiotics for Broiler Chickens—<i>In Vitro</i> Design and Evaluation of the Influence on Host and Selected Microbiota Populations following <i>In Ovo</i> Delivery - Fig 2
Published 2017“…The highest dose that did not decrease hatchability (10<sup>5</sup> cfu egg<sup>-1</sup> of prebiotic and 2 mg egg of probiotic) was selected for the field trial. …”
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64652
Ultrastructure and immunofluorescent staining of the macrodactylous enlarged nerve (MEN) and normal digital nerve (NDN) tissue.
Published 2018“…(B) MEN tissue showed a significant decrease in the number of myelinated nerve fibers compared with those in NDN tissue (scale bars, 5.0 nm) and collagen density of the nerve fibers was distinctly increased (B, white arrows) (C) The diameter of the myelinated fiber was apparently reduced in the new regenerative nerve structures (C, yellow arrows), which was found in Berrettini anastomosis (BA) (scale bars, 5.0 nm). …”
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64653
Temporal distribution of scFv-h3D6 through the extra- and intracellular brain compartments.
Published 2019“…<p>(A) Extracellular (continuous line, top) and intracellular (dashed line, bottom) scFv-h3D6 levels are represented over time p.i.: 0h (for vehicle-injected mice), 1h, 5h, 10h, 1 day, 2 days, 5 days, and 8 days. …”
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64654
The transcriptional activities of FASN in SKBR3, MCF-7and MCF-7/HER2 breast cancer cells treated with mTOR inhibitor rapamycin.
Published 2014“…<p>A, The transcriptional activities of FASN promoter in the three cells were all inhibited treated with rapamycin (2.5 nmol/L, 4 h) and the inhibition effect showed more significant in MCF/HER2 cell lines than in MCF-7 and SKBR3 cell lines (p<0.05). …”
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64655
Random forest identified stop codon identity, P-site amino acid identity, and 3’-UTR length as factors critical in readthrough efficiency prediction.
Published 2021“…<p><b>A.</b> Performance metric for random forest regression displaying average Normalized Root Mean Squared Error (NRMSE) ± standard deviation across 5-fold cross-validation. …”
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64656
Effects of lycopene on ER stress inducer (thapsigargin, TG)-induced changes in neonatal cardiomyocytes.
Published 2015“…The total proteins of cardiomyocytes were extracted and the protein expression levels of Bip/GRP78 and GADD153 were detected by western blot. (A) TG evoked a dose-dependent decrease in the viability of neonatal cardiomyocytes. …”
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64657
Combination of cetuximab and trametinib was more effective in the partially responsive group ex vivo.
Published 2017“…E, Western blots of lysates from the reconstituted spheroids treated with or without 100 nM cetuximab, 5 nM trametinib, or a combination of 100 nM cetuximab and 5 nM trametinib for 2 h with or without stimulation with 10 ng/ml EGF for 15 min.…”
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64658
<i>In vitro</i> reductase activity with furfural and HMF as substrates in crude cell extracts from the strains MD4, MD4.1 and GVM1, the latter two each containing one copy of <i>AS...
Published 2021“…For each condition, at least three technical repeats were used. (A) 2.5 mM and 5 mM furfural with NADH, (B) 5 mM furfural with NADPH, (C) 10 mM HMF with NADPH. …”
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64659
Fig 2 -
Published 2022“…<p>GO annotations and KEGG pathways first enriched at (A) 13–18 and 7–12 months before diagnosis and (B) 1–6 months before diagnosis. …”
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64660
DataSheet1_Neuroprotective Effects of Oligosaccharides From Periplaneta Americana on Parkinson’s Disease Models In Vitro and In Vivo.zip
Published 2022“…The data demonstrated that OPA significantly reversed the MPP<sup>+</sup>-induced decrease in SH-SY5Y cell viability, reduced the proportion of apoptotic cells, and protected SH-SY5Y cells from apoptosis in a dose-dependent manner by regulating the expression of apoptosis-related genes. …”