Potential mechanisms for the reducing BRCA1 expression by Christopher R Mueller (1657)

“…Methylation of both promoters through an unidentified mechanism would lead to a dramatic decrease in expression. Increased NBR2 expression could lead to decreased BRCA1 expression. p53 could inhibit factors such as E2F. …”

Relative quantities (RQ) of <i>amTOR</i> mRNA levels in honey bee larvae. by Avani Patel (30611)

“…<p>In colonies a–b, queen- (Q) and worker-destined (W) larvae are characterised by a transient two-fold difference in <i>amTOR</i> expression (present in 3^rd instar larvae, absent in spinning 5^th instar larvae). …”

The autophagy enhanced by downregulation of Chk-α contributed to protect MCF-7/TAM cells from tamoxifen. by Hoe Suk Kim (107279)

“…(B) Western blot analysis of the p62. 3-MA caused to a slight decrease in p62 level in MCF-7/TAM-shChk-α cells. …”

Immunohistochemical staining and quantification of brain sections using LFB and MBP. by Marwan Chami (4068142)

“…<p>Cuprizone treatment for 5- or 12-weeks causes a massive decrease in myelination as determined by LFB and MBP staining in the CCm <b>(a)</b>. …”

Glycogen synthase knockdown inhibits autophagosome growth and improves CQ-induced myopathy phenotype. by Jonathan Zirin (483506)

“…(K) <i>UAS</i>–<i>GlyS</i> RNAi caused a highly significant decrease in the mean vesicle size (area) compared to the control. …”

Image_1_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.jpg by Laura Melado (3990398)

“…For women <45 years old, the decrease in AFC was between -0.6/-0.8 per year. Up to 36 years old, the decrease of AMH was 0.1ng/ml. …”

Image_3_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.jpg by Laura Melado (3990398)

“…For women <45 years old, the decrease in AFC was between -0.6/-0.8 per year. Up to 36 years old, the decrease of AMH was 0.1ng/ml. …”

Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Table_1_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.docx by Laura Melado (3990398)

“…For women <45 years old, the decrease in AFC was between -0.6/-0.8 per year. Up to 36 years old, the decrease of AMH was 0.1ng/ml. …”

Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Image_2_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.jpg by Laura Melado (3990398)

“…For women <45 years old, the decrease in AFC was between -0.6/-0.8 per year. Up to 36 years old, the decrease of AMH was 0.1ng/ml. …”

Table_2_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.docx by Laura Melado (3990398)

“…For women <45 years old, the decrease in AFC was between -0.6/-0.8 per year. Up to 36 years old, the decrease of AMH was 0.1ng/ml. …”

HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons by Maryline Santerre (6101399)

“…Viruses and retroviruses such as HIV-1 are known to manipulate autophagy in order to use it for their replication while blocking the degradative final step, which could destroy the virus itself. Our study highlights how the suppression of neuronal autophagy by HIV-1 Vpr is a mechanism leading to toxic protein aggregation and neurodegeneration.…”

NK cells are affected differently by allogeneic grafts depending on the course of rejection. by Oliver Beetz (6786137)

“…Syngeneic HTx served as a control group (n = 5). (B) Flow cytometric assessment of frequencies of NK cells in Lew wt and Lew.1a recipients after syngeneic and allogeneic HTx compared to naïve rats, respectively. …”

DataSheet1_One-dimensional modeling of heterogeneous catalytic chemical looping steam methane reforming in an adiabatic packed bed reactor.pdf by Haris Qayyum (17415264)

“…At the optimum temperature (950 K), pressure (1 bar), and steam-to-carbon molar ratio (3/1), with an increase in particle diameter from 0.7 to 1 mm, an 18% decrease in methane conversion and a 9.5% increase in hydrogen yield were observed. …”

Pol II occupancy is reduced at genes affected by P-TEFb depletion. by Olle Dahlberg (645665)

“…(<b>B</b>) Western blot with extracts from 0–5h old embryos show a decrease in Ser2-P in embryos depleted of maternal Cdk9 or CycT. …”

DataSheet1_Experimental investigation of mechanical and durability performances of self-compacting concrete blended with bagasse ash, metakaolin, and glass fiber.docx by Monali Wagh (19447753)

“…Additionally, there was a decrease of 29.4% in the percentage of charges passed. …”

Iron(III)-Mediated C–H Alkylation: One-Electron Differentiation Increases Activity and Chemoselectivity by Tianyi Zhang (87298)

“…The effect of bis­(phosphine) ligands was examined, where decreasing ligand lability correlated with a higher barrier. …”

Qualitative comparison between multiple models of frequency-specific anaesthesia effect and data obtained in vivo. by Luciana López-Jury (8601540)

“…Frequency-specific effects were implemented as a decrease of the cortical input firing rate (“input”) or an increase of presynaptic adaptation (“presyn”), either one of them (1 to 8) or both (9 to 12). …”

TLC analysis of simple lipids. by Agata Leszczynska (117214)

“…<p>A significant drop in the level of sterol precursors in cells cultivated in the presence of simvastatin indicates that the ergosterol intermediates were efficiently converted to ergosterol. …”