The effect of a simultaneous V-ATPase inhibition and membrane permeabilization in spherical versus various sized disc-shaped lysosomes. by Tehetina Woldemichael (4579546)

“…For all of the disc-shaped lysosomes, as the lysosomal radius and height increased and decreased, respectively, more increment in the lysosomal pH, more reduction in the lysosomal Cl^- accumulation, and a slight increment in the lysosomal membrane potential were observed when there were no or very minimal alterations in both the V-ATPase number and membrane proton permeability, thus indicating the effect that the change in morphology alone has on lysosomal physiology.…”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Supplementary Material for: Somatic variants and exon-level copy number changes in five hyperplastic-stage oral leukoplakias. by Anne A. (13992672)

“…We performed exome sequencing of five cases at this stage with no evidence of dysplasia to identify genetic alterations (exon-level copy number alterations, indels, and single nucleotide variants), their association with transcript levels and relationship with oral cancer susceptibility. …”

Figure S1 - The RNA Degradation Pathway Regulates the Function of GAS5 a Non-Coding RNA in Mammalian Cells by Hidenori Tani (169942)

“…<p><b>Knockdown of UPF1 increases the expression level of GAS5, and decreases the glucocorticoid-responsive genes.…”

Hepatic B1 cells increase whereas PC B1 cells decrease after <i>S</i>. <i>japonicum</i> infection. by Liang Yong (6836771)

Comparison of the diffusion properties of GABA_AR γ2 and α5 in inhibitory and excitatory synapses. by Marianne Renner (142651)

“…<p>(A–B) Cumulative probabilities of diffusion coefficients of γ2 and α5 in inhibitory (green, inh) and excitatory synapses (red, exc) <i>vs</i>. the extrasynaptic membrane (black, ex). …”

Nampt inhibition leads to decrease in Rev-erb alpha expression and glucagon secretion in alphaTC1-9 cells and pancreatic alpha cells. by Elaine Vieira (174928)

“…<p>(<b>A</b>) <i>Sirt1</i> gene expression in alphaTC1-9 cells treated with 0.5 mM, 11 mM glucose or 500 nM FK 866 for 6 hours (n = 7). …”

Synaptic recruitment of α5-GABA_ARs contributes to wake-dependent enhancement of iLTP. by Kunwei Wu (725668)

“…<p>(A) Time course of mIPSC amplitude in hippocampal CA1 pyramidal cells before and after NMDA application. α5-GABA_AR inverse agonist L655,708 was applied 20 min post-NMDA application. …”

Validation of the regulatory activities of FMN, TPP riboswitches and a putative 5’-UTR regulatory candidate in different nutrient conditions. by Indu Warrier (581139)

“…<p>The relative expression and average RNA-Seq coverage of SP_0178 (FMN) <b>(A)</b> and SP_0716 (TPP) <b>(C)</b> increases in poor (MCDM) medium compared to rich (SDMM) medium, potentially compensating for the depletion of the specific ligand. …”

Data_Sheet_5.XLSX by Behzad Bidadi (4953235)

“…<p>Neutropenia secondary to chemotherapy in breast cancer patients can be life-threatening and there are no biomarkers available to predict the risk of drug-induced neutropenia in those patients. We previously performed a genome-wide association study (GWAS) for neutropenia events in women with breast cancer who were treated with 5-fluorouracil, epirubicin and cyclophosphamide and recruited to the SUCCESS-A trial. …”

Analysis of Monte Carlo simulations of 109–122 and 109–122 A₁₁₇V peptide monomers. by Andrew C. Gill (198299)

“…Simulation temperatures are given in materials and methods and as the temperature is increased so the overall frequency of helical structure decreases. (C) and (D) frequency of β-sheet structure around each amino acid as a function of temperature for 109–122 and 109–122 A₁₁₇V peptides respectively. …”

miR-26a-5p protects against drug-induced liver injury via targeting bid by Qian Zhang (49333)

“…</p> <p>miR-26a-5p expression was greatly decreased in HSCs and serum treated with azithromycin, simvastatin and diclofenac sodium, respectively. …”

Analysis of Monte Carlo simulations of 106–126 and 106–126 A₁₁₇V peptide monomers. by Andrew C. Gill (198299)

“…Simulation temperatures are given in materials and methods and as the temperature is increased so the overall frequency of helical structure decreases. (C) and (D) frequency of β-sheet structure around each amino acid as a function of temperature for 106–126 and 106–126 A₁₁₇V peptides respectively. …”

Persistence of antibody to 23-valent pneumococcal polysaccharide vaccine: a 5-year prospective follow-up cohort study by Xiang Guo (223678)

“…</p> <p>Overall, 517 participants completed all six visits over a 5-year period (2013–2018). The GMC of 23 serotypes in adults aged ≥ 60 years decreased slowly after PPV23 vaccination compared to baseline pre-vaccination (<i>P</i> < 0.05), except serotype 3. …”

Image_5_Rhizosphere Microbial Communities Are Significantly Affected by Optimized Phosphorus Management in a Slope Farming System.JPEG by Qianxin Deng (11424451)

“…However, the effects of different phosphorus (P) managements on soil microbial communities in a slope farming system are poorly understood. Here, rhizosphere microbial communities under two P fertilization levels—conventional (125 kg P₂O₅ ha^–1, P125) and optimal (90 kg P₂O₅ ha^–1, P90)—were compared at four growth stages of maize in a typical sloped farming system. …”