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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
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Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress
Published 2021“…In this study, we demonstrate that FKBP4 decrease in a human neuronal cell line (SH-SY5Y) and in dorsal root ganglion (DRG) neurons from human MAPT<sup>P301S</sup> transgenic mice affected the function of the autophagy-lysosomal system under MAPT induced proteotoxic stress conditions. …”
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Flow chart of the study procedures.
Published 2023“…Pre-treatment spontaneous decrease of RPR titer was associated with a slower decrease in post-treatment RPR titer.…”
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Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival.
Published 2020“…The error bars for all data presented in Fig 2 represent the mean ± SEM. Results demonstrate that TPP derivatives decrease melanoma cell viability and clonogenic survival; and there is a structure-activity relationship between TPP side chain length and decreased viability and clonogenic survival.…”
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