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13981
Antibodies to PfRH5 and PfCyRPA modify temporal aspects of the pre- and post-invasion phases of <i>Plasmodium falciparum</i> into human RBCs.
Published 2023“…<p>(A-E) The invasion steps being monitored from live cell videos of antibody-treated parasites are indicated on the y-axes. …”
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13982
Sequence analysis of continually RDV selected SARS-CoV-2<sub>Engl2</sub>.
Published 2021“…Calculated from 988 mutations observed in minimum of 5 sequences. Position of mutation associated with decrease RDV sensitivity in SARS-CoV-2 is highlighted in red and sites identified in murine hepatitis virus (MHV) and Ebola virus (EBOV) are indicated in black. …”
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13983
Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms
Published 2025“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”
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13984
Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms
Published 2025“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”
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13985
Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms
Published 2025“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”
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13986
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13987
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13988
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13989
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13990
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13991
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13992
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13993
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13994
A proposed model illustrates the dynamic and profound interaction of host polyamine biosynthesis and eIF5A hypusination with KSHV infection.
Published 2022“…Lytic switch of KSHV also drive an early upregulation of eIF5A and the correlated increase of hyp-eIF5A. On the contrary, at the late stage of lytic replication expression of KSHV latent proteins diminishes, leading to decrease of ODC1 and reduction of intracellular polyamines. …”
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13995
Visible-Light Paternò–Büchi Reaction for Lipidomic Profiling at Detailed Structure Levels
Published 2023“…Around 90% conversion can be achieved at high concentrations (>0.5 mM) for different classes of lipids but drops as the lipid concentration decreases. …”
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13996
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13997
Optical coherence tomography findings.
Published 2024“…After PCI, hDPV significantly increased from 55.6 cm/s to 69.5 cm/s (P<0.01), with a median %hDPV increase of 27.2 (6.32–59.1) %, while %hDPV decreased in 20 (19.4%) patients. …”
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13998
S1 Data -
Published 2024“…After PCI, hDPV significantly increased from 55.6 cm/s to 69.5 cm/s (P<0.01), with a median %hDPV increase of 27.2 (6.32–59.1) %, while %hDPV decreased in 20 (19.4%) patients. …”
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13999
Clinical demographics and angiographic findings.
Published 2024“…After PCI, hDPV significantly increased from 55.6 cm/s to 69.5 cm/s (P<0.01), with a median %hDPV increase of 27.2 (6.32–59.1) %, while %hDPV decreased in 20 (19.4%) patients. …”
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14000
Physiological parameters.
Published 2024“…After PCI, hDPV significantly increased from 55.6 cm/s to 69.5 cm/s (P<0.01), with a median %hDPV increase of 27.2 (6.32–59.1) %, while %hDPV decreased in 20 (19.4%) patients. …”