Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter by Laura László (3221631)

“…The recently published high resolution structure of a close homologue, the ABCG5-ABCG8 heterodimer, revealed a new ABC transporter fold, unique for ABCG proteins. …”

Impaired Ubr5 function results in increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

Average velocity per 5% of the distance during normal and 3, 4, and 5 kg assisted 60 m sprints for men and women. by Roland van den Tillaar (6407390)

Most miRNAs in Ago1 RISC are stable with age whereas transposon siRNAs in Ago2 RISC decrease with age. by Siobhan Gartland (14129274)

“…(B) miRNAs in Ago1 RISC from old and young females are plotted as percentage of mapped reads. miR-34-5p and miR-14-3p do not change by 2-fold. miR-318-3p and miR-994-5p decrease by 2-fold with age. …”

Correlations between SARS-CoV-2 specific T cells and FEV₁ and symptoms in PASC. by Katherine M. Littlefield (12647420)

Higher concentrations of HDACi LBH589 further increase PR and decrease Myc expression in endometrial cancer cells. by Tamar Kavlashvili (849072)

Validation of a New Scoring Scale for Behavioral Assessment of L‑Dopa-Induced Dyskinesia in the Rat: A New Tool for Early Decision-Making in Drug Development by Simon Loiodice (4715610)

“…The rating scale was sensitive enough to highlight a dose-dependent amantadine-mediated decrease (about 2.2-fold) in LID score. …”

Computational Prediction and Analysis of Envelop Glycoprotein Epitopes of DENV-2 and DENV-3 Pakistani Isolates: A First Step towards Dengue Vaccine Development by Hafsa Amat-ur-Rasool (702613)

“…There is no effective vaccine available, so far, against any of its four serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). There is a need for the development of preventive and therapeutic vaccines against DENV to decrease the prevalence of dengue fever, especially in Pakistan. …”

Inhibition of ALK4/5/7 decreases Sertoli cell proliferation in E12.5 fetal testes. by Denise C. Miles (218867)

Administration of APB5, but not APA5, decreases the hyperplasia of alveolar type 2 epithelial cells induced by BLM. by Masami Kishi (6167105)

“…The administration of APB5 markedly decreased the hyperplasia of type 2 epithelial cells induced by BLM. …”

Activation of ERα with estrogen simultaneously increases PR expression and decreases Myc expression in endometrial cancer cells. by Tamar Kavlashvili (849072)

Effects of decreased NSUN2 and METTL1 expression on 5-FU-treatment and heat stress and 5-FU. by Mayumi Okamoto (280005)

Decreased ratio of GSH/GSSG in <i>Slc1a1-</i>HET mice. by Parisa Afshari (4423141)

Gene deletion on chromosome 10. by Sophia Bigot (16469992)

DOM assembly monitored with temperature and pH reveals that, as either pH decreases or temperature increases, microgel equilibrium size and assembly rates decrease at a non-linear... by Chi-Shuo Chen (234719)

Attenuation of spheroid size decrease or MUC5AC increase by hit compounds. by Pranjali Beri (14945400)

“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”

Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain. by Caio Maximino (100467)

“…<p>(A) Turnover rates, as measured by 5-HIAA:5-HT ratios, normalized to the values of vehicle-treated animals, for the following drugs: fluoxetine (FLX; chronic treatment with 10 mg/kg); chlordiazepoxide (CDZ; 0.02 mg/kg); clonazepam (CLZ; 0.05 mg/kg); diazepam (DZP; 1.25 mg/kg); buspirone (BUS; 50 mg/kg); ethanol (EtOH, 2.5%); dizocilpine (MK; 0.005 mg/kg); verapamil (VER; 5 mg/kg); WAY 100,635 (WAY; 0.03 mg/kg); and SB 224,289 (SB; 2.5 mg/kg). …”

Five compounds significantly decrease MAPK1 phosphorylation in K562 cells. by Pamela Y. Ting (713174)

Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice. by Katherine R. Sadleir (12035242)

“…<p><b>(</b>A and F) Representative immunoblots of hippocampal (A) and cortical (F) lysates of non-transgenic and 5XFAD mice treated with vehicle or nimodipine. …”

The number of Affymetrix probe ID, expressions of which were increased or decreased by neonatal estradiol bezoate (EB) treatment, in the hypothalamus of female mice. by Mototsugu Sakakibara (479337)