Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair by Nicole Bennardo (93380)

“…These results suggest that the regulation of DSB end-processing via KU/CtIP is a common step during alt-NHEJ, SSA, and HDR/GC. …”

Progress in Lipid Droplet Simulations: How Polarizability Shapes Triacylglycerol Behavior in Bulk and Interfacial Environments by R. Jay Braun (21988628)

Data Sheet 1_Pathologic complete response after neoadjuvant therapy for locally advanced rectal cancer in a real-world setting: a population-based study.docx by Lina Cadili (21448478)

“…Aim<p>This study aimed to determine the impact of time from neoadjuvant therapy (NAT) to surgery on the complete pathologic response (pCR) rate in patients with locally advanced rectal cancer. NAT decreases the local recurrence of rectal cancer. Some patients achieve a pCR. …”

Baseline characteristics. by Nattapat Nitinai (17896679)

“…The montelukast group exhibited a decreased incidence rate of transaminase elevations (0.7% vs 1.4% per day, HR: 0.48, 95%CI 0.25–0.90, P = 0.023).…”

Subgroup analyses for the primary outcome. by Nattapat Nitinai (17896679)

“…The montelukast group exhibited a decreased incidence rate of transaminase elevations (0.7% vs 1.4% per day, HR: 0.48, 95%CI 0.25–0.90, P = 0.023).…”

Outcomes. by Nattapat Nitinai (17896679)

“…The montelukast group exhibited a decreased incidence rate of transaminase elevations (0.7% vs 1.4% per day, HR: 0.48, 95%CI 0.25–0.90, P = 0.023).…”

Trial profile. by Nattapat Nitinai (17896679)

“…The montelukast group exhibited a decreased incidence rate of transaminase elevations (0.7% vs 1.4% per day, HR: 0.48, 95%CI 0.25–0.90, P = 0.023).…”

Mutagenesis of the CXCL10 binding site on <i>L</i>. <i>(L</i>.<i>) major</i> GP63 to <i>L</i>. <i>(V</i>.<i>) panamensis</i> residues reduces CXCL10 cleavage and T cell chemotaxis. by Alejandro L. Antonia (7147739)

“…(L.) major gp63 <i>allele (D463) to the</i> L. (V.) panamensis <i>allele (N463) at the CXCL10 binding site decreases CXCR3</i>^<i>+</i> <i>T cell chemotaxis</i>. …”

Synthesis of a Dialuminum-Substituted Silicotungstate and the Diastereoselective Cyclization of Citronellal Derivatives by Yuji Kikukawa (1929586)

“…The reaction of <b>1</b> with pyridine yielded TBA₃[(C₅H₅N)H][γ-SiW₁₀O₃₆{Al(C₅H₅N)}₂(μ-OH)₂]·2H₂O (<b>2</b>), and the molecular structure was successfully determined by the X-ray crystallographic analysis. …”

Synthesis of a Dialuminum-Substituted Silicotungstate and the Diastereoselective Cyclization of Citronellal Derivatives by Yuji Kikukawa (1929586)

“…The reaction of <b>1</b> with pyridine yielded TBA₃[(C₅H₅N)H][γ-SiW₁₀O₃₆{Al(C₅H₅N)}₂(μ-OH)₂]·2H₂O (<b>2</b>), and the molecular structure was successfully determined by the X-ray crystallographic analysis. …”

Bacterial strains used in this study. by Malin-Theres Seffer (14808772)

“…<i>aureus</i> in human plasma was approximately 5 x 10⁸ cells.</p><p>Conclusions</p><p>The Seraph affinity filter, based on heparin-coated beads, is a highly efficient method for reducing <i>S</i>. …”

Stability of FeF₃‑Based Sodium-Ion Batteries in Nonflammable Ionic Liquid Electrolytes at Room and Elevated Temperatures by Zifei Sun (11576725)

“…The Pyr_1,4FSI electrolyte demonstrated the best cycling stability with an unprecedented decay rate of only ∼0.023% per cycle after the initial stabilization and an average coulombic efficiency of ∼99.5% for over 1000 cycles at RT. The Pyr_1,3FSI electrolyte demonstrated the best cycling stability with a capacity decay rate of only ∼0.25% per cycle at 60 °C. …”

ABCA1 plays a key role in the inhibition of HCV infection. by Simone Bocchetta (539356)

“…<p>(A) Silencing of ABCA1. Huh7.5 cells were transfected with siRNA that targets ABCA1, or with a control siRNA. …”

<i>Foxj1</i> as a target gene for RFX4. by Ping Xu (122619)

“…<p>(A) qPCR. <i>Foxj1</i> mRNA levels were decreased in E12.5 KO brains, whereas there were no significant differences in <i>Ift172</i>, <i>Thbs</i>, <i>Dync2li1</i>, <i>Rfx2</i>, <i>Rfx3</i> mRNAs, and almost undetectable <i>Rfx4</i> transcripts compared to the controls (P< 0.0001, n = 5). …”

AS-IV attenuated Aβ1-42-induced mitochondrial dysfunction. by Qinru Sun (573895)

“…Mitochondria were counterstained with Mitotracker Green (green fluorescence). (a) vehicle; (b) 50 µM AS-IV; (c) 5 µM Aβ1-42; (d, e, f) 10, 25, 50 µM AS-IV+ 5 µM Aβ1-42, respectively. …”

A stratified transcriptomics approach for adipose tissue-specific gene enrichment. by Nicholas M. Morton (206471)

“…From top to bottom; 1. differential gene expression (>1.5-fold) between the lines across all adipose tissues was analysed with a ‘snap-shot’ pooled transcriptomics approach. 2. …”

Dynamics of different T-cell subpopulations and estimated production rates including confidence intervals. by Sara P. H. van den Berg (8703927)

Effect of the probiotic powder on colorectal cancer. by Xiaojuan Yang (794374)

<i>In vivo</i> settling down and effects of N₂ and O₂ exposure on oxygen currents. by Pier Andrea Serra (475322)

“…The prolonged exposure (5 min) to pure oxygen, in a sealed chamber, induced a sustained increase (C) increase of the oxygen currents (* = p <0.001 vs baseline) in about half an hour (# = p<0.001 vs O₂ exposure). …”

The background acts as a buffer of free subunits for LLPS-dominated assembly. by Michael F. Hagan (2109034)

“…For the case without LLPS, the parameters are the same except that <i>K</i>_c = 1 and the increasing rate is achieved by scaling the subunit-subunit affinities according to <i>sg</i>_nuc and <i>sg</i>_elong with <i>s</i> ∈ [1, 1.5]. The results stop at <i>s</i> = 1.5 because stronger affinities lead to kinetic traps and thus poor yields and a decreasing maximum rate.…”