Table_5_Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants.XLSX by Dominik Modrzejewski (5639621)

“…In addition, we ran a binary logistic regression analysis to verify five factors that may affect the occurrence of off-target effects: (1) Number of mismatches (2) Position of mismatches (3) GC-content of the targeting sequence (4) Altered nuclease variants (5) Delivery methods. …”

Image_5_Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs.PDF by Qinglei Xu (8497341)

“…A total of 400 weaned pigs [Duroc × (Landrace × Yorkshire)] were randomly allocated into one of four treatments: the CON group, fed with basic diet; the HM1 group, fed with basal diet supplemented with 0.5 g herbal mixture/kg diet; the HM2 group, fed with basal diet supplemented with 1.0 g herbal mixture/kg diet; or the HM3 group, fed with basal diet supplemented with 1.5 g herbal mixture/kg diet. …”

Insulin resistance following the acute administration of the antipsychotic drugs risperidone and paliperidone, measured with the hyperinsulinemic euglycemic clamp. by Heidi N. Boyda (10048024)

Impaired fibronectin and fibrinogen-cleaving activities of the E143A and H146A Zmp1 mutants. by Valeria Cafardi (490077)

“…(<b>C</b>) Decreased ability of E143A and H146A Zmp1 mutants to cleave fibronectin. 1 µM fibronectin from human plasma was incubated for 24 h at 37°C with no Zmp1 (control) or with 7.7 µM of wild type (WT), E143A or H146A Zmp1 in the presence of 0.5 mM ZnCl₂. 1 µg of fibronectin was analyzed by SDS-PAGE and Coomassie-blue staining. …”

FIGURE 5 from Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor by Shruti Lal (16805936)

“…<p>Phosphoproteomic screen identifies MCM2 Ser108 phosphorylation decreased by ZL-2201. <b>A,</b> Simple Western showing inhibition of pDNA-PK upon treatment with PRKDC siRNA, 300 nmol/L and 3.5 μmol/L of ZL-2201 ± 10 μmol/L bleomycin used in phospho-MS screen analysis. …”

Decreased NK1.1^pos iNKT cell numbers in the peripheral organs of T cell-specific <i>Gfi1</i>-deficient mice. by Toshiaki Yasuoka (2827457)

Underlying data for Figs 6, S5, and S6. by Kun Wu (286745)

Flow chart. by Raphaele Houlbracq (20558509)

“…The difference in overall prevalence of OASI between 2010 (0.7%) and 2021 (1.0%) was not statistically significant after adjustment (aRR 1.24, 95% CI 0.91 to 1.68). By groups of classification, the prevalence of OASI increased significantly only in Group 2b [nulliparous term cephalic singleton with spatula delivery] from 2.6% (95% CI 1.2 to 5.6) in 2010 to 9.6% (95% CI 6.2 to 14.7) in 2021 (aRR 3.69, 95% CI 1.50 to 9.09), and did not differ statistically significantly in Group 2a [nulliparous term cephalic singleton with forceps delivery] from 3.2% (95% CI 1.8 to 5.7) in 2010 to 5.7% (95% CI 3.4 to 9.5) in 2021 (aRR 1.78, 95% CI 0.81 to 3.90).…”

Data_Sheet_1_Mental health across two years of the COVID-19 pandemic: a 5-wave longitudinal study in Germany.PDF by Maxi Weber (12420430)

Table 5_Dynamic proteomics reveals that endosperm weakening plays a critical role during seed germination in Polygonatum cyrtonema Hua.xlsx by Huilong Xu (1358961)

In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin by Stephanie A. Eytcheson (4284421)

“…Initial screening at a single high concentration of 100 μM identified 714 chemicals that decreased signal of the bound fluorescent ligand by 20% or higher. …”

Table_5_The Effect of Dexmedetomidine on Emergence Agitation or Delirium in Children After Anesthesia—A Systematic Review and Meta-Analysis of Clinical Studies.DOC by Yuquan Rao (9118304)

Video_5_Programmable Attenuation of Antigenic Sensitivity for a Nanobody-Based EGFR Chimeric Antigen Receptor Through Hinge Domain Truncation.avi by Scott McComb (234597)

Image5_Pan-cancer analysis of the prognosis and immunological role of AKAP12: A potential biomarker for resistance to anti-VEGF inhibitors.tif by Qiuju Liang (588501)

Label-Free Proteomics Reveals Decreased Expression of CD18 and AKNA in Peripheral CD4⁺ T Cells from Patients with Vogt-Koyanagi-Harada Syndrome by Liming Mao (231467)

“…The results revealed that the expression of 102 peptides was significantly altered (p<0.05) between two groups and matched amino acid sequences of proteins deposited in the international protein index (ipi.HUMAN.v3.36.fasta). The identified peptides corresponded to 64 proteins, in which 30 showed more than a 1.5-fold difference between the two groups. …”

Table1_Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study.xlsx by Helison R. P. Carmo (19810212)

“…Diacerein has emerged as a potential therapy for COVID-19 due to its potential impact in decreasing the inflammasome activation and coronavirus replication. …”

Image_5_Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses.jpeg by Giulia Monticone (13431972)

Data_Sheet_5_Construction and Analysis of a ceRNA Network in Cardiac Fibroblast During Fibrosis Based on in vivo and in vitro Data.PDF by Qing-Yuan Gao (10013927)

“…Finally, two mRNA [ADAM metallopeptidase domain 19, (ADAM19) and transforming growth factor beta induced, (TGFBI)], three microRNA (miR-9-5p, miR-124-3p, and miR-153-3p) and two lncRNA (LINC00511 and SNHG15) constituted our ceRNA network. siRNA against LINC00511 increased miR-124-3p and miR-9-5p expression, and decreased ADAM19 and TGFBI expression, whereas siRNA against SNHG15 increased miR-153-3p and decreased ADAM19 expression. …”

Curcumin inhibits EV71 infection-induced PKCδ phosphorylation. by Hsing-I Huang (1627360)

Table5_SVInterpreter: A Comprehensive Topologically Associated Domain-Based Clinical Outcome Prediction Tool for Balanced and Unbalanced Structural Variants.xlsx by Joana Fino (3182070)