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19641
αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
Published 2015“…To elucidate the mechanism, siRNAs against β5 integrin, CD36, Mer tyrosine kinase (MerTK), and Atg5, blocking antibodies against CD36 and MerTK, and a specific inhibitor for focal adhesion kinase (FAK) were used. …”
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19642
Slope coefficients of herbivore density (individuals.km<sup>-2</sup>) along a gradient of increasing woody cover (e.g. for a 10% increase in woody cover on the basalts, the impala...
Published 2015“…</p><p>This illustrates that browsers increase with increasing woody cover, whilst most grazers decrease. (**** 0.01% significance level; *** 0.1% significance level; ** 1% significance level; * 5% significance level; when applying a Bonferroni correction for 24 tests, only species indicated as significant at the ≤0.1% level will remain significant at the 5% level).…”
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19643
Syntheses of Pentanuclear Group 6 Iridium Clusters by Core Expansion of Tetranuclear Clusters with Ir(CO)<sub>2</sub>(η<sup>5</sup>‑C<sub>5</sub>Me<sub>4</sub>R) (R = H, Me)
Published 2013“…Metal cluster core expansion at tetrahedral group 6–group 9 mixed-metal clusters MIr<sub>3</sub>(μ-CO)<sub>3</sub>(CO)<sub>8</sub>(η<sup>5</sup>-L) (M = W, Mo, L = C<sub>5</sub>H<sub>5</sub>; M = Mo, L = C<sub>5</sub>Me<sub>5</sub>) with the iridium capping reagents Ir(CO)<sub>2</sub>(η<sup>5</sup>-L′) (L′ = C<sub>5</sub>Me<sub>5</sub>, C<sub>5</sub>Me<sub>4</sub>H) in refluxing toluene afforded the trigonal-bipyramidal clusters MIr<sub>4</sub>(μ-CO)<sub>3</sub>(CO)<sub>7</sub>(η<sup>5</sup>-C<sub>5</sub>H<sub>5</sub>)(η<sup>5</sup>-L′) (M = Mo, L′ = C<sub>5</sub>Me<sub>5</sub>, <b>1a</b>; M = W, L′ = C<sub>5</sub>Me<sub>5</sub>, <b>1b</b>; M = Mo, L′ = C<sub>5</sub>Me<sub>4</sub>H, <b>1c</b>; M = W, L′ = C<sub>5</sub>Me<sub>4</sub>H, <b>1d</b>) and MoIr<sub>4</sub>(μ<sub>3</sub>-H)(μ-CO)<sub>2</sub>(μ-η<sup>1</sup>:η<sup>5</sup>-CH<sub>2</sub>C<sub>5</sub>Me<sub>4</sub>)(CO)<sub>7</sub>(η<sup>5</sup>-C<sub>5</sub>Me<sub>5</sub>) (<b>2</b>). …”
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19644
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19645
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19646
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19647
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19648
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19649
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19650
Presentation_1_Risk of severe COVID-19 infection in persons with diabetes during the first and second waves in Denmark: A nationwide cohort study.pdf
Published 2022“…However, when mortality was restricted to the hospitalized population, the crude mortality fell from 26.8% to 19.6% in persons with diabetes, while only a minor decrease was seen in persons without diabetes (from 16.7% to 15.5%).…”
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19651
Hysteretic Spin Crossover between a Bisdithiazolyl Radical and Its Hypervalent σ-Dimer
Published 2010“…The value of σ<sub>RT</sub> for β-<b>1a</b> (near 10<sup>−4</sup> S cm<sup>−1</sup> at 0.5 GPa) initially decreases with pressure as the phase change takes place, but beyond 1.5 GPa this trend reverses, and σ<sub>RT</sub> increases in a manner which parallels the behavior of α-<b>1a</b>. …”
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19652
Hysteretic Spin Crossover between a Bisdithiazolyl Radical and Its Hypervalent σ-Dimer
Published 2010“…The value of σ<sub>RT</sub> for β-<b>1a</b> (near 10<sup>−4</sup> S cm<sup>−1</sup> at 0.5 GPa) initially decreases with pressure as the phase change takes place, but beyond 1.5 GPa this trend reverses, and σ<sub>RT</sub> increases in a manner which parallels the behavior of α-<b>1a</b>. …”
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19653
Hysteretic Spin Crossover between a Bisdithiazolyl Radical and Its Hypervalent σ-Dimer
Published 2010“…The value of σ<sub>RT</sub> for β-<b>1a</b> (near 10<sup>−4</sup> S cm<sup>−1</sup> at 0.5 GPa) initially decreases with pressure as the phase change takes place, but beyond 1.5 GPa this trend reverses, and σ<sub>RT</sub> increases in a manner which parallels the behavior of α-<b>1a</b>. …”
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19654
Hysteretic Spin Crossover between a Bisdithiazolyl Radical and Its Hypervalent σ-Dimer
Published 2010“…The value of σ<sub>RT</sub> for β-<b>1a</b> (near 10<sup>−4</sup> S cm<sup>−1</sup> at 0.5 GPa) initially decreases with pressure as the phase change takes place, but beyond 1.5 GPa this trend reverses, and σ<sub>RT</sub> increases in a manner which parallels the behavior of α-<b>1a</b>. …”
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19655
Hysteretic Spin Crossover between a Bisdithiazolyl Radical and Its Hypervalent σ-Dimer
Published 2010“…The value of σ<sub>RT</sub> for β-<b>1a</b> (near 10<sup>−4</sup> S cm<sup>−1</sup> at 0.5 GPa) initially decreases with pressure as the phase change takes place, but beyond 1.5 GPa this trend reverses, and σ<sub>RT</sub> increases in a manner which parallels the behavior of α-<b>1a</b>. …”
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19656
Effects of Prednisolone on Disease Progression in Antiretroviral-Untreated HIV Infection: A 2-Year Randomized, Double-Blind Placebo-Controlled Clinical Trial
Published 2016“…Secondary endpoints: Prednisolone-treatment decreased immune activation (sCD14, suPAR, CD38/HLA-DR/CD8+) and increased CD4-counts (+77.42 ± 5.70 cells/μl compared to -37.42 ± 10.77 cells/μl under placebo, p < 0.0001). …”
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19657
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19658
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19659
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
Published 2019“…The long-term antidiabetic efficacies of <b>5</b> (10 mg/kg, qw) were better than those of the once-weekly trelagliptin and omarigliptin, especially in decreasing the hemoglobin A1c level.…”
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19660