Reduced RNA expression of the <i>FMR1</i> gene in women with low (CGG_n<26) repeats by Qi Wang (22418)

“…The main outcome measure was RNA expression in human luteinized granulosa cells of 5 groups of FMRP isoforms. The relative expression of FMR1 RNA in human luteinized granulosa cells was measured by real-time PCR and a possible association with CGG_n was explored. …”

Inhibition of RhoA by Rhosin blocked phosphorylation of myosin light chain and platelet shape change. by Huzoor Akbar (340517)

“…<b>(C-D)</b> Aspirin (1 mM) treated washed human platelets containing apyrase (3 U/ml) were incubated with U46619 (0.01 μM) or thrombin (0.005 U/ml) and platelet shape change was recorded as a decrease in light transmittance using a Lumi-Aggregometer. …”

TBI accelerated extracellular Aβ deposits in the cortex of AD mice that received TBI. by Naoki Tajiri (106215)

Genesis of Soils from Bauxite in Southeastern Brazil: Resilication as a Soil-Forming Process by Ana Carolina Campos Mateus (4642963)

The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology by Mohsen Sadatsafavi (63962)

“…<div><p>Background</p><p>There is minimal evidence on the extent to which the occurrence of a severe acute exacerbation of COPD that results in hospitalization affects the subsequent disease course. …”

Gene expression profiles of DKK1, CYR61, CTGF, TGFBR1, COL3A1, COL1A1, ITGA2, MMP14, MMP2, TIMP2, TIMP1, TIMP3. by Hermann Agis (660951)

“…Data points represent 5 samples</p>…”

Table_1_Daily Intake of a Phaseolus vulgaris L. Snack Bar Attenuates Hypertriglyceridemia and Improves Lipid Metabolism-Associated Plasma Proteins in Mexican Women: A Randomized Cl... by Aurea K. Ramírez-Jiménez (12750107)

“…A modest body weight (5%) reduction was also found. …”

Core–Shell {Mn₇⊂(Mn,Cd)₁₂} Assembled from Core {Mn₇} Disc by Ling-Yu Guo (3068232)

“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn₁₃Cd₆, Mn₁₄Cd₅ and Mn₁₅Cd₄, having a distribution of metals. …”

Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week... by Takashi Kadowaki (35402)

“…</p> <p><b>Research design and methods</b>: We randomized 240 patients with type 2 diabetes mellitus on insulin monotherapy to 5-mg saxagliptin or placebo as add-on therapy for a 16-week, double-blind period. …”

Alexia Searchfield: Born Too Small? Is this a risk factor for low educational attainment? by Alexia Kate Searchfield (4080514)

RPIA regulates colon cell proliferation through β-catenin expression in HCT116 cells. by Yu-Ting Chou (447778)

“…<i>AXIN2</i>, <i>Axis inhibition protein 2</i>; <i>CCND1</i>, <i>Cyclin D1</i>; <i>CCNE2</i>, <i>Cyclin E2</i>; <i>CTNNB1</i>, <i>CATENIN BETA 1</i>; pcDNA, pcDNA3 vector control; qPCR, quantitative PCR; RPIA, ribose-5-phosphate isomerase A; si-NC, negative control small interfering RNA; si-RPIA, RPIA small interfering RNA; TCF, T-cell transcription factor.…”

An idealized view of the opportunity provided by a comparative and integrated oncology drug development path. by Ira Gordon (369869)

“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”

Temperature-Induced Phase Transitions of Vivianite: In Situ Analysis of a Redox-Driven Crystallization by Alice Paskin (10017280)

Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study by Jennifer E. Nyland (11412878)

“…Use of DPP-4 inhibitors was associated with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95% CI, 0.74-0.90]; <i>P</i> <.001), and continued use of DPP-4 inhibitors after hospitalization was associated with a decrease in mortality compared with those who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; <i>P</i> <.001). …”

Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX by Dohee Lee (432106)

“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”

A simplified methodology for the analysis of the establishment of hydrokinetic parks downstream from hydroelectric plants by Paulo André Vasco Barbosa (5342219)

High mRNA expression of <i>Slc6a15</i> in CNS. by Maria G. A. Hägglund (386708)

Possible pathways involved in GBE-induced neuroplasticity pathway. by Imane Lejri (8066507)

FIGURE 1. Antimicrobial resistance for hospital strains (n=4,375) and study panel (n=180). by Marine Pottier (14099133)

Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus -7 by Michele Menotta (55040)