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63301
Sociodemographic characteristics of the sample.
Published 2024“…Effects on purchase intentions were smaller, with a 6% decrease for unsustainable products (p = 0.001) and an 8% increase for sustainable products (p<0.001). …”
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63302
DataSheet1_Human organoids are superior to cell culture models for intestinal barrier research.docx
Published 2023“…Here we performed a detailed functional characterization of human intestinal organoid cultures under different conditions with the aim to suggest an optimized ex-vivo model to further analyse inflammation-induced intestinal epithelial barrier dysfunction. …”
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63303
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63304
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63305
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63306
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63307
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63308
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63309
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63310
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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63311
On the apical centrosome, Cnb localized on the daughter centriole partially originates from the mother centriole.
Published 2020“…Error bars indicate standard deviation of the mean. Cnb intensity was plotted as a ratio of centrosomal/cytoplasmic Cnb (S/N; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000762#sec012" target="_blank">Methods</a>) in panels C, E, and F. …”
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63312
Impact of MCD mediated cholesterol depletion on NT formation.
Published 2011“…Incubation of cells with 1.25 mM MCD led to comparatively short NT lengths (arrowhead) whereas incubation with 2.5 mM MCD led to extended NT lengths (arrow). All data are means ± SEM. * p<0.05, ** p<0.01 (<i>t</i>-test in <b>A</b>).…”
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63313
Functional significance of Rsu-1.
Published 2013“…<p>A) Overexpression of Rsu-1 leads to a significant decrease in Hep3B proliferation. …”
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63314
Robotic Thoracic Enucleation of Esophageal Leiomyoma
Published 2023“…Because of the lesion’s anterior position relative to the trachea, it was felt it might be best accessed from the right chest. We also felt that potential risk of left recurrent laryngeal nerve injury may be decreased with a right-sided approach.…”
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63315
Data_Sheet_1_Fire Promotes Arsenic Mobilization and Rapid Arsenic(III) Formation in Soil via Thermal Alteration of Arsenic-Bearing Iron Oxides.PDF
Published 2019“…Here, we subject an organic-rich soil (∼15% organic C) mixed (4:1) with As(V)-bearing ferrihydrite and goethite (total As of 2.8–3.8 μmol g<sup>-1</sup>), to various temperatures (200–800°C) and heating durations (5–120 min) and examine the consequences for As and Fe via X-ray absorption spectroscopy, X-ray diffraction, <sup>57</sup>Fe Mössbauer spectroscopy and selective extracts. …”
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63316
Presentation_1_Nicotinic Receptors in the Brainstem Ascending Arousal System in SIDS With Analysis of Pre-natal Exposures to Maternal Smoking and Alcohol in High-Risk Populations o...
Published 2021“…Overall, there was a developmental decrease in <sup>125</sup>I-epibatidine binding with increasing postconceptional age in 5 medullary sites [raphe obscurus, gigantocellularis, paragigantocellularis, centralis, and dorsal accessory olive (p = 0.0002–0.03)], three of which are nuclei containing serotonin cells. …”
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63317
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63318
Nanosecond Pulsed Electric Field Suppresses Development of Eyes and Germ Cells through Blocking Synthesis of Retinoic Acid in Medaka (<i>Oryzias latipes</i>)
Published 2013“…<div><p>Application of nanosecond pulsed electric fields (nsPEFs) has attracted rising attention in various scientific fields including medical, pharmacological, and biological sciences, although its effects and molecular mechanisms leading to the effects remain poorly understood. Here, we show that a single, high-intensity (10–30 kV/cm), 60-ns PEF exposure affects gene expression and impairs development of eyes and germ cells in medaka (<i>Oryzias latipes</i>). …”
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63319
Choice asymmetry.
Published 2022“…Bold markers and errorbars are bootstrapped means and 95% confidence intervals. Filled markers denote a significant population shift away from 0.5 (<i>p</i> < 0.05). …”
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63320
Supplementary Material for: Successful Reperfusion with Endovascular Therapy Has Beneficial Effects on Long-Term Outcome Beyond 90 Days
Published 2019“…We defined improvement and deterioration as decrease and increase on the mRS score by 1 point or more from 90 days to 1 year after endovascular therapy respectively. …”