Effects of microtubule-active drugs on actin filaments and mitochondrial movements. by Maozhong Zheng (263386)

“…Scale bar = 10 µm. C. A growing root hair treated with 5 µM taxol showing an increase in fluorescence in the subapical and apical regions and an aggregation of thick actin bundles in the very tip of the hair, concomitant with a decrease in the basal shank. …”

Data_Sheet_1_Staphylococcus aureus Infection Influences the Function of Intestinal Cells by Altering the Lipid Raft-Dependent Sorting of Sucrase–Isomaltase.PDF by AhmedElmontaser Mergani (11271159)

“…The data show that there is no significant change in the overall expression levels of SI in the infected versus non-infected cells as assessed by Western blotting analysis using monoclonal anti-SI antibodies. By contrast, a significant decrease in the localization as well as the specific hydrolytic activities of SI toward sucrose and isomaltose (Palatinose) was observed in the BBM (P2 fraction) in Caco-2 cells 48 h post-infection. …”

Mechanistic framework predicts drug-class specific utility of antiretrovirals for HIV prophylaxis by Sulav Duwal (152805)

“…Notably, some drugs from this candidate set are patent-expired and currently neglected for PrEP repurposing. A next step is to further trim this candidate set by ruling out compounds with ominous safety profiles, to assess different administration schemes in silico and to test the remaining candidates in human trials.…”

DataSheet1_Wave Equation Numerical Simulation and RTM With Mixed Staggered-Grid Finite-Difference Schemes.docx by Wei Liu (20030)

“…For acoustic wave modeling, with almost identical computational costs, M-SFD can achieve higher modeling accuracy than C-SFD. Moreover, with a larger time step used in M-SFD than that used in C-SFD, M-SFD can achieve higher computational efficiency and reach higher modeling accuracy. …”

Proposed epigenetic regulatory mechanism during the somatic embryogenesis of <i>Coffea canephora</i>. by Geovanny I. Nic-Can (448043)

“…These findings suggest that dynamic changes in chromatin could be a crucial step for switching genes on or off during the dedifferentiation and differentiation events to develop a somatic embryo. …”

Hospitalizations for primary care-sensitive conditions in Pelotas, Brazil: 1998 to 2012 by Juvenal Soares Dias da Costa (4657279)

Example of the spatiotemporally complex oscillatory dynamics associated with verb processing by Ryan T. Canolty (86909)

Effect of natural feed additives on meat quality and caecotrophic fatty acid profile of New Zealand rabbits by Isabelle Zocolara NÓIA (10406253)

The alternate biochemical experiments to test for apoptosis under all the growth conditions and markers for oxidative stress. by Hung-Chih Hsu (479317)

“…Values in each box express cellular percentages of decreased mitochondrial transmembrane potential. The values shown are mean ± standard deviation (n = 5–8). …”

Genome-wide screen controls and primary results. by Yolande Grobler (5959106)

“…(<b>B)</b> The whole genome screen yielded 1117 primary hits with a robust Z score of ≥1.5 or ≤-1.5. These genes included 329 genes that increase <i>Wolbachia</i> (magenta) and 788 genes that decrease <i>Wolbachia</i> (green) upon RNAi knockdown. …”

Temperature stress facilitates colonization of <i>H</i>. <i>oligactis</i> by <i>T</i>. <i>parva</i> and tumor formation. by Kai Rathje (8599788)

“…<b>(B)</b> Temperature stress results not only in a decrease of <i>Pseudomonas</i> OTU750018 relative abundance, but also in a significant decrease of density (absolute abundance). …”

Ozone therapy as an adjuvant for endondontic protocols: microbiological – ex vivo study and citotoxicity analyses by Carlos Goes NOGALES (12833419)

“…The cytotoxicity assay showed Groups III and IV to be the most aggressive, providing a decrease in cell viability at hour 0 from 100% to 77.3% and 68.6%, respectively. …”

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization by Kun Liu (148201)

“…To assess the effects of decreased macrophage autophagy on inflammation, mice with a <i>Lyz2</i>-<i>Cre</i>-mediated knockout of <i>Atg5</i> in macrophages were fed a HFD and treated with low-dose lipopolysaccharide (LPS). …”

RT-PCR detection of NLRPs in human oocytes and embryos showed two expression patterns. by Pu Zhang (51027)

“…<p>A: <i>NLRP4, 5, 8, 9, 11,12, 13 and 14</i> were highly expressed in oocytes and then gradually decreased in embryos with a very low level in day5 (D5) embryos. …”

Discriminability of sound contrasts in the face of speaker variation quantified by Christina Bergmann (557788)

Comparative sensitivity of the test with tuberculosis recombinant allergen, containing ESAT6-CFP10 protein, and Mantoux test with 2 TU PPD-L in newly diagnosed tuberculosis childre... by Liudmila Slogotskaya (6111866)

“…</p><p>Conclusion</p><p>In children and adolescents with active tuberculosis, Diaskintest of 0.2 μg/ml and the Mantoux test with 2 TU PPD-L have high sensitivity (98%) at a cut-off of 5 mm; however, at cut-off ≥ 15 mm sensitivity is significantly reduced, and the decrease is more pronounced in the Mantoux test. …”

Cdk1 inhibition reproduces the loss of FlnB phenotypes. by Jianjun Hu (19574)

“…(B) Flow cytometry following propridium iodide (PI) labeling shows a decrease in the number of ATDC5 cells in G2/M phase and an increase in the number of ATDC5 cells in G1/G0 phase in the Cdk1 inhibitor (1 µM) treated cells compared to control. …”

Effect of deletion of the functional domains of INS-20 on <i>Cryptosporidium parvum</i>. by Yue Huang (285485)

“…Mice infected with the transgenic lines of INS-20ΔNter, INS-20ΔCter, and INS-20^HLLEQ/5A showed a 3-fold decrease in fecal luciferase activity compared to those infected with the IId-GFP line. …”

Figure S1 - Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord by Sharyn L. Rossi (244876)

“…There was a 5-fold decrease in NGF expression in hMNP when compared to hFibs (b) Western blot analysis confirming that hMNP express and secerete NT-3, NT-4, NGF, and VEGF.…”

Figure S1 - Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord by Sharyn L. Rossi (244876)

“…There was a 5-fold decrease in NGF expression in hMNP when compared to hFibs (b) Western blot analysis confirming that hMNP express and secerete NT-3, NT-4, NGF, and VEGF.…”