Image_2_OCT4 and SOX2 Specific Cytotoxic T Cells Exhibit Not Only Good Efficiency but Also Synergize PD-1 Inhibitor (Nivolumab) in Treating Breast Cancer Stem-Like Cells and Drug-R... by Wei Peng (432211)

“…Besides, PD-1 inhibitor (nivolumab) improved the cytotoxic activity of OCT4&SOX2 CTLs against MCF7-BCSCs in a dose-dependent manner. In vivo, OCT4&SOX2 CTLs plus PD-1 inhibitor (nivolumab) decreased tumor volume and tumor weight while increased tumor apoptosis rate compared to OCT4&SOX2 CTLs alone, PD-1 inhibitor (nivolumab) alone, and control.…”

Image_4_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…T cells and resident macrophages (rMP) were the largest populations in the normal cornea comprising 18.6 and 18.2 percent, respectively. rMP increased to 55.2% of cells after 5 days of DS. Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. …”

Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (<i>Danio rerio</i>) by Gai Ran (4234048)

“…<div><p>Defective lipid metabolism is associated with increased risk of various chronic diseases, such as obesity, cardiovascular diseases, and diabetes. Resveratrol (RSV), a natural polyphenol, has been shown the potential of ameliorating disregulations of lipid metabolism. …”

Response surface analysis factor level table. by Yong-gang Huang (9931922)

“…The disintegration at pH = 4.2 was increased by 11.4% and 22.4% compared to pH = 5.6 and pH = 7, respectively. The acidity affects soil disintegration is due to the hydrophilic minerals in the expansive soil react with H⁺ ion in the acid solution to form soluble salts. …”

Image_7_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…T cells and resident macrophages (rMP) were the largest populations in the normal cornea comprising 18.6 and 18.2 percent, respectively. rMP increased to 55.2% of cells after 5 days of DS. Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. …”

DataSheet2_Investigation of the Anti-Inflammatory Activity of Fusaproliferin Analogues Guided by Transcriptome Analysis.ZIP by Qi-Xuan Kuang (11773529)

“…Surface plasmon resonance assays (SPR) combined with molecular docking analyses were finally applied to evaluate the affinity interactions between 1-4 and TLR4 and provide a possible interpretation of the downregulation of related signaling pathways.…”

Schematic diagram of disintegration device. by Yong-gang Huang (9931922)

“…The disintegration at pH = 4.2 was increased by 11.4% and 22.4% compared to pH = 5.6 and pH = 7, respectively. The acidity affects soil disintegration is due to the hydrophilic minerals in the expansive soil react with H⁺ ion in the acid solution to form soluble salts. …”

DataSheet2_Investigation of the Anti-Inflammatory Activity of Fusaproliferin Analogues Guided by Transcriptome Analysis.ZIP by Qi-Xuan Kuang (11773529)

“…Surface plasmon resonance assays (SPR) combined with molecular docking analyses were finally applied to evaluate the affinity interactions between 1-4 and TLR4 and provide a possible interpretation of the downregulation of related signaling pathways.…”

Table_1_Testosterone and soluble ST2 as mortality predictive biomarkers in male patients with sepsis-induced cardiomyopathy.docx by Lu Wang (45927)

“…During the 28 days and 90 days follow-up, 87 (26.6%) and 103 deaths (31.5%) occurred, respectively. Kaplan–Meier analysis showed significantly higher 28 days and 90 days survival in patients with higher testosterone and decreased sST2 levels (p < 0.001). …”

Image_3_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…T cells and resident macrophages (rMP) were the largest populations in the normal cornea comprising 18.6 and 18.2 percent, respectively. rMP increased to 55.2% of cells after 5 days of DS. Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. …”

DataSheet2_Investigation of the Anti-Inflammatory Activity of Fusaproliferin Analogues Guided by Transcriptome Analysis.ZIP by Qi-Xuan Kuang (11773529)

“…Surface plasmon resonance assays (SPR) combined with molecular docking analyses were finally applied to evaluate the affinity interactions between 1-4 and TLR4 and provide a possible interpretation of the downregulation of related signaling pathways.…”

DataSheet_1_Etiologic characteristics revealed by mNGS-mediated ultra-early and early microbiological identification in airway secretions from lung transplant recipients.xlsx by Xiaoqin Zhang (517854)

“…Fungi such as Candida are also frequently detected. 5 (50%) microbial species identified by microbial culture had multiple drug resistance (MDR). …”

DataSheet_2_The Efficacy and Safety of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Combined With Thymosin in Advanced Non-Small Cell Lung Cancer Patients Harboring A... by Yongdong Feng (10891662)

“…The median OS was also prolonged in EGFR-TKI plus thymosin group than that in EGFR-TKI group (29.5 months vs. 19.8 months; HR=0.430, 95% CI 0.319 - 0.580, P<0.0001). …”

Image_6_Comprehensive evaluation of the mechanism of Gastrodia elata Blume in ameliorating cerebral ischemia–reperfusion injury based on integrating fecal metabonomics and 16S rDNA... by Ximeng Ding (14018481)

“…The present study has shown a significant effect of G. elata Blume in improving cerebral ischemia–reperfusion injury (CIRI). …”

Analysis of PM high confidence Runx1-regulated genes. by Kfir Baruch Umansky (783699)

“…<p>(A) Schematic representation of the selection procedures used to identify high-confidence Runx1-regulated genes. …”

<i>Otx2</i> requires <i>Lmx1b</i> for the development of mdDA neurons. by Orna Sherf (804524)

“…<p>Representative coronal midbrain section of E12.5 WT (A-B, K-L), <i>En1</i>^+/Otx2(C-D, M-N), <i>Lmx1b</i>^<i>-/-</i> (E-F, O-P) and <i>En1</i>^+/Otx2; <i>Lmx1b</i>^<i>-/-</i> (G-H, Q-R) embryos. …”

DataSheet_1_Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages via TWIK2-mediated potassium efflux.pdf by Yingqin Wang (4924222)

“…S1P exerts most of its function by binding to S1P receptors (S1PR1-5). The roles of S1P receptors in NLRP3 inflammasome activation remain unclear.…”

Ruthenium Carbene Complexes Analogous to Grubbs‑I Catalysts Featuring Germylenes as Ancillary Ligands by Lucía Álvarez-Rodríguez (1478374)

“…Complex <b>7</b> arises from a <i>trans</i>-to-<i>cis</i> isomerization of intermediate <b>6</b>. …”

Systematic review of accuracy of reporting of Congo red-stained amyloid in 2010–2020 compared with earlier by Alexander J. Howie (13817900)

The co-opted function of cytosolic Pgk1 is to provide ATP for viral replicase complex assembly. by K. Reddisiva Prasanth (693252)

“…<p>(A) Northern blot analysis shows decreased TBSV (+) and (-)repRNA accumulation in a yeast strain (GALS::PGK1) when Pgk1 was depleted (raffinose) in comparison when Pgk1 expression is induced (Gal+Raf). …”