HuR regulates expression of Eph/ephrins. by Jennifer Winter (87429)

“…Quantification of bands (Against GAPDH) was performed using the Image Quant software 5.2 (lower panel). Fold increase or decrease of expression are depicted.…”

Blood clearance and subsequent in vivo degradation of BK- and JC-virus like particles (VLPs). by Jaione Simon-Santamaria (3598871)

“…<p>Mice were injected intravenously with approximately 0.5 µg of ¹²⁵I-BK-VLPs (n = 3; A, B), or ¹²⁵I-JC-VLPs (n = 5; C, D), and blood samples taken at the indicated time points and analyzed for ¹²⁵I-labeled degradation products and intact ligand <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0111762#pone.0111762-Malovic1" target="_blank">[15]</a>. …”

Pressure Dependence of the Carbon Dioxide/Cyclohexene Oxide Coupling Reaction Catalyzed by Chromium Salen Complexes. Optimization of the Comonomer-Alternating Enchainment Pathway by Donald J. Darensbourg (1317624)

“…The most active (salen)CrN₃ catalyst (H₂salen = <i>N</i>,<i>N</i>‘-bis(3-<i>tert</i>-butyl-5-methoxysalicylidene)-(1<i>R</i>,2<i>R</i>)-cyclohexenediimine), along with a [PPN][N₃] cocatalyst, exhibited a TOF of 1153 mol epoxide consumed/mol chromium·h at 80 °C and a CO₂ pressure of 34.5 bar.…”

Synaptic facilitation between tail SNs and MNs following sensitizing tail shocks declined during aging. by Andrew T. Kempsell (738294)

“…<p>A) Representative responses during depolarizing current injection in tail SNs before and 5 min after sensitizing tail shocks in mature and aged II animals. …”

Overall influence of the levels of stimulation on behavioral thresholds and latencies. by Jean-Michel Benoist (270919)

“…On average, the behavioral threshold Tβ was 44.9 (44.5–45.3)°C with a significant tendency to decrease from the proximal to the distal parts of the tail, best described by the equation Tβ = 47.4−0.014 D (F_44,1 = 12.2; p<0.01). …”

Intracellular chloride measurements by Wallace B Thoreson (5462)

“…An example of the reduction in MEQ fluorescence, indicating an increase in intracellular [Cl], produced by application of 12.1 mM Kto a cone. C. A greater decrease in MEQ fluorescence was produced by application of 69.9 mM K. …”

Heat map of the miRNAs that are regulated at different times following MCAo. by Fu Jia Liu (422650)

“…Green: downregulation; Red: upregulation. (<b>A</b>) The expression of 334 miRNAs that are statistically significant are represented in the heat map; (<b>B</b>) Cluster of miRNAs that show a decrease in expression during the progression of cerebral ischemia (rno-miR-196a, -196b, -196c, -224, -324-3p); (<b>C</b>) Cluster of miRNAs that show an increase in expression during the progression of cerebral ischemia (rno-miR-21, -142-3p/5p, -146a); (<b>D</b>) Cluster of miRNAs that show an expression which positively correlated with infarct volume during the progression of cerebral ischemia (rno-miR-206, -290, -291a-5p and -30c-1*).…”

Immobilization of Burkholderia cepacia on Pristine or Functionalized Multi-Walled Carbon Nanotubes and Application on Enzymatic Resolution of (RS)-1-Phenylethanol by Michele R. G. Dias (5668394)

“…This pristine or functionalized BCL/MWCNTs system could be reused for up to 8 times without significant decrease in the catalytic efficiency. Under the optimum conditions (pH of immobilization 6.0, 45 ºC and 25 mg/5 mg pristine or functionalized BCL/MWCNTs), the best results were obtained using BCL immobilized on MWCNTs-A. …”

Purification and characterization of His-tagged PhaZ_UD. by Tomohiro Morohoshi (5735813)

“…(B) The PHBH-degrading activity of His-tagged PhaZ_UD. A total of 200 μL of purified PhaZ_UD sample was mixed with 800 μL of 5 mg/mL PHBH solution in a 1.5 mL microtube. …”

Heat map of the miRNAs that are regulated at different times following MCAo. by Fu Jia Liu (422650)

“…Green: downregulation; Red: upregulation. (<b>A</b>) The expression of 334 miRNAs that are statistically significant are represented in the heat map; (<b>B</b>) Cluster of miRNAs that show a decrease in expression during the progression of cerebral ischemia (rno-miR-196a, -196b, -196c, -224, -324-3p); (<b>C</b>) Cluster of miRNAs that show an increase in expression during the progression of cerebral ischemia (rno-miR-21, -142-3p/5p, -146a); (<b>D</b>) Cluster of miRNAs that show an expression which positively correlated with infarct volume during the progression of cerebral ischemia (rno-miR-206, -290, -291a-5p and -30c-1*).…”

Substrate binding specificity of purified OpuAC. by Justina C. Wolters (207763)

“…<p>Binding was measured using intrinsic protein fluorescence at an OpuAC concentration of ∼0.5 µM. The following substrates were tested: proline (panel A), carnitine (panel B), proline betaine (panel C) and glycine betaine (Panel D–F). …”

Label-free real-time multi-parametric monitoring enables high content analysis. by Heinz-Georg Jahnke (122745)

“…The effect on the APD was determined for one hour after doxorubicin application and revealed a concentration dependent response with an EC₅₀ value of 17 µM (n  = 3 hCMC), (B) The impedance analysis revealed a concentration- and time-dependent decrease where IC₅₀ values could be determined for each time point (n  = 5 hCMC). …”

Inhibition of NF-κB signaling impedes TNF-α-induced increase in proliferation and angiogenic signaling. by Michael Boyle (433024)

“…(<b>B</b>) MTT assay showing a decrease in TNF-α-induced increase in proliferation, in DPSC challenged with varying concentrations of NBD domain peptide (5 and 10 µM). …”

MtNFP and MtLYK3, or AtCERK1 (co-)production in <i>Nicotiana</i> leaves induces defence-like responses. by Anna Pietraszewska-Bogiel (417871)

“…<i>Agrobacterium</i> transformants carrying either <i>MtNFP-3xFLAG</i> or <i>MtLYK3-3xFLAG</i> construct were co-infiltrated into <i>Nicotiana</i> leaves at five different time points (1–5). Macroscopic observation (left panel) and subsequent Evans blue staining (right panel) are depicted 42 hai (region 1), 39 hai (region 2), 36 hai (region 3), 33 hai (region 4) and 30 hai (region 5). …”

HIV/AIDS case definition criteria and association between sociodemographic and clinical aspects of the disease reported in the State of Minas Gerais from 2007 to 2016 by Sybelle de Souza Castro (5668175)

“…By contrast, a consequent decrease was observed in the number of criteria used for defining cases, which were adapted from the Centers for Disease Control and Prevention, Rio de Janeiro/Caracas, and for identifying AIDS-related deaths. …”

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age by Delio Eulalio Martins (5759282)

“…</p><p>Results</p><p>The old-aged group showed a decrease in content of sulphated and non-sulphated glycosaminoglycans relative to middle-aged and there were also alterations in the proportion of GAG disaccharides and a decrease of collagen fiber size. …”

Acute Toxicity of Silver Free and Encapsulated in Nanosized Zeolite for Eukaryotic Cells by Clément Anfray (3923939)

“…After exposure to Ag⁺-EMT (50 μg/mL) for 24 h, a loss in cell viability independent of the cell type was observed, ranging from −34.37 ± 23.90% for astrocytes to −99.5 ± 0.24% for U87-MG cells. …”

Donor and Geometry Optimization: Fresh Perspectives for the Design of Polyoxometalate Charge Transfer Chromophores by Bethany R. Hood (20396768)

“…The linear systems show that with julolidinyl (Jd) and −NTol₂ donor groups, the alkyne bridge yields high second-order nonlinear optical (NLO) coefficients β (Jd, β_0,<i>zzz</i> = 318 × 10^–30 esu; −NTol₂, β_0,<i>zzz</i> = 222 × 10^–30 esu), indeed the Jd compound gives the highest NLO activity of any organoimido-POM to date with minimal decrease in transparency. The <i>bis</i>-functionalized 2D (<i>C</i>_2v) POM derivative showed increased activity over its monofunctionalized analogue with no decrease in transparency, although the NLO response was only minimally two dimensional. …”

Cadaveric cardiosphere-derived cells can maintain regenerative capacity and improve the heart function of cardiomyopathy by Yong Sun (406434)

“…CLH-EDCs were also found to have similar paracrine function in the 24 h group compared to 0 h group. 8 weeks after CM-CDCs transplantion to the injured heart, mean left ventricular ejection fraction increased in both 0 h (64.99 ± 3.4%) and 24 h (62.99 ± 2.8%) CM-CDCs-treated groups as compared to the PBS treated group (53.64 ± 5.6 cm), with a decrease in left ventricular internal diastolic diameter (0.29 ± 0.08 cm and 0.32 ± 0.04 cm in 0 h and 24 h groups, vs. 0.41 ± 0.05 cm in PBS group). …”

The peak energies of the fits of individual measured Ti Kβ spectra by C T Chantler (557430)

“…The peak energy of the titanium Kβ spectral profile is found to be 4931.966 ± 0.022 eV prior to instrumental broadening. This 4.5 ppm result decreases the uncertainty over the past literature by a factor of 2.6 and is 2.4 standard deviations from the previous standard. …”