Modeling the RA Morphogen Gradient by Richard J White (82003)

“…Values of parameters that differed between panels were β = 1 ([A–E] and solid curve in [G]) or 0.5 ([F], [H], and dashed curve in [G]); <i>x</i>_f = 400 μm ([A–C] and [F–H]) or 450 μm (D–E); <i>f</i>₀ = 0 (B), 400 ([A], [C], [F–H], and solid curves in [D] and [E]), or 1,100 (dashed curves in [D] and [E]); <i>k</i>_deg = 500 sec⁻¹ ([A] and [C–G]) or 0.03 sec⁻¹ (B); <i>k</i>_max = 0.001 ([A] and [C–G]) or 4 (B); <i>V</i>(<i>x</i>) = 5 for <i>x</i> > <i>x</i>_f – 40, zero otherwise ([A], [D], [E], and solid curves in [B], [C], and [G]), 2.5 for <i>x</i> > <i>x</i>_f – 40, zero otherwise (dashed curves in [B] and [C]), 0.2 for all <i>x</i> ([F], dashed curve in [G], and solid curve in [H]), or 0.1 for all <i>x</i> (dashed curve in [H]).…”

COMPARE-MS assay performance by Srinivasan Yegnasubramanian (27577)

“…When 20–100 ng of input DNA are used, COMPARE-MS has a >5000-fold dynamic range, which is ∼500-fold higher than that of methylation-sensitive restriction enzyme used alone and ∼5- to 10-fold higher than that of MBD2-MBD capture used alone. () Plot showing measured output methylated CGIs as determined by COMPARE-MS when decreasing amounts of M.SssI-treated WBC DNA is diluted in 20 ng of untreated WBC genomic DNA. …”

File S1 - Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor by Carola E. Bunse (492512)

“…After 48 h of storage at 4°C, a mean of 93% (mCMV_pp65_A02, n = 4) and 96% (mCMV_pp65_B07, n = 5) of the frequency in the fresh sample (baseline) was obtained. …”

The coevolution of effort and replication, replicated and corrected by Florian Kohrt (13918527)

“…The replication was successful with one exception. We find that selection acting on scientist’s propensity for replication frequency caused a brief period of exuberant replication not observed in the original paper due to a coding error. …”

HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells. by Paramita Saha (473954)

“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”

DataSheet_1_Treatment With Lipopolysaccharide Induces Distinct Changes in Metabolite Profile and Body Weight in 129Sv and Bl6 Mouse Strains.docx by Maria Piirsalu (8627697)

“…According to the general linear model analysis (GLM), the 1.5 h LPS challenge in Bl6 caused a decrease of propionylcarnitine (C3), glucogenic amino acids, and acetylornithine (Ac-Orn), whereas the response of 129Sv included decreased concentrations of short-chain acylcarnitines (SCACs), citrulline, and elevation of glycerophospholipid (PCaa C42:0) and sphingolipid [SM(OH)C16:1]. 24 h after LPS administration, robust alterations in lipid profile were observed in both strains. …”

Evaluation of the reproductive barriers between species. by Robin Gras (57789)

“…<p>(<b>A</b>) Mean and standard deviation (error bars) of the rate of hybrid production before (red) and after (blue) 10000 time steps. …”

Infiltration of blood clots by cancer cells. by Stephanie Rossnagl (553093)

“…(F) Evaluation of cancer cell numbers when injected 5 minutes after clot induction showed a significant decrease in the number of cancer cells detected in the bone marrow at 1 hour after clot induction (p<0.05) but not at later time points (4, 24 and 48 hours after clot induction) (p = ns). n = 4–8 per time point.…”

Table1_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.DOC... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table8_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XLS... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table7_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XLS... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table4_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XLS... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table2_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.doc... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table6_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XLS... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table10_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XL... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table9_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XLS... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Table3_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.doc... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis was performed to investigate pre- and post-competition EV concentration and size distribution. A panel of 179 miRNAs was assayed by qPCR and analyzed by Exiqon GenEx v6 normalized on the global mean. t-miRNA and EV-miRNAs whose level was ≥5-fold up- or down-regulated were validated for each single subject. …”

Supplementary Material for: Trends in One-Year Recurrent Ischemic Stroke among the Elderly in the USA: 1994–2002 by Allen N.B. (4121671)

“…After adjustment for changing patient demographics and comorbidities, there was a 4.5% decrease in recurrent stroke rates from 1994–1996 (13.2%) to 2000–2002 (12.6%; p for trend <0.0001). …”

Data Sheet 1_Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure.docx by Bochao Ma (14572143)

“…</p>Results<p>Compared to the control group, the Young's modulus of the glial LC decreased by 35.5%, 74.2%, and 80.6% at 4, 8, and 12 weeks of elevated IOP, respectively. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…Cells of the ventricular and subventricular zones of the cortex show strongest decrease in staining intensity (black arrowhead). Scale bar equals 400 µm; ctx, cortex; th, thalamus; cpt, caudoputamen; cp, cortical plate; iz, intermediate zone; svz, subventricular zone; vz, ventricular zone; sn, septal nuclei; 3v, third ventricle; lv, lateral ventricle; pc, choroid plexus.…”