Image_2_Effects of Combined Oxytocin and Beta-3 Receptor Agonist (CL 316243) Treatment on Body Weight and Adiposity in Male Diet-Induced Obese Rats.jpg by Melise M. Edwards (11405780)

Effects of cold stress and <i>Salmonella Heidelberg</i> infection on bacterial load and immunity of chickens. by Atilio Sersun Calefi (477173)

Tumor microenvironment facilitates the emergence of high levels of drug resistance. by Feng Fu (218124)

“…Parameters: tumor size <i>N</i> = 10¹¹, <i>τ</i>_<i>g</i> = <i>τ</i>_<i>c</i> = 1cm, <i>D</i>₀ = 500, <i>b</i>₀ = 0.5, <i>d</i>₀ = 0.4, <i>M</i> = 30, <i>n</i> = 3, IC₅₀ = 50, <i>m</i> = 2, <i>s</i> = 0.01, <i>ρ</i> = 5, <i>u</i> = 10⁻⁹, <i>v</i> = 2×10⁻⁴.…”

Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells by Yong-Chao Ma (174419)

“…The viabilities of 6 different cancer cell lines treated with a range of HMNE3 doses were detected using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”

The acetaminophen metabolite AM404 produces antinociception by activation of TRPV₁ in the brain. by Christophe Mallet (241657)

“…<p>(A) Intracerebroventricular (i.c.v.) injection of AM404 (10 nmol) 5 min before injection of formalin into the mouse hind paw decreased biting and licking during the first, but not the second phase of the formalin test (n = 5–6). …”

Table_1_Ten-Eleven Translocation (TET) Enzymes Modulate the Activation of Dendritic Cells in Allergic Rhinitis.DOCX by Hang Li (123039)

“…</p><p>Methods: The levels of TETs in peripheral blood mononuclear cells (PBMCs), peripheral myeloid DCs (mDCs), and plasmacytoid DCs (pDCs) from house dust mite (HDM)-sensitive AR patients and healthy volunteers (HC) were evaluated by qPCR and flow cytometry. The levels of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) in PBMCs were determined by DNA-5hmC and DNA-5mC ELISA. …”

The effect of salts, pH and additives in the lysis buffer on the solubility of RGP1. by Ditte Hededam Welner (4099906)

“…Buffers 13 and 19–21, containing 1-2M salt, as well as the low-pH (4.3–5.5) buffers 11,12,15, 22 and 30 decrease the amount of soluble RGP1, while lower salt concentrations as well as several additives increase the amount of soluble RGP1 relative to the standard lysis buffer (std: 50 mM HEPES pH 8.0, 250 mM NaCl, 5 mM MgCl₂). …”

Grid division diagram. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Model calculation diagram. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Grid independence verification. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

DataSheet1.pdf by Vincent Portero (518206)

“…Using computer simulations employing a multicellular in silico model, we furthermore demonstrate that the experimentally observed increase in K_V4.3 current and concurrent decrease in Na_V1.5 current may result in a loss of conduction, underlining the potential functional relevance of our findings. …”

Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis by Joycilene da Silva Barbosa (12731788)

“…Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. …”

Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis by Joycilene da Silva Barbosa (12731788)

“…Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. …”

Table_2_Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy.XLSX by Yufei Chen (206648)

“…Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. …”

Secondary screening and ‘hit’ validation. by Ilona Tkachyova (343715)

“…Treatment with 1.2 μM of SAHA resulted in a ~ 40% decrease in NDST enzyme activity. Experiments were conducted in triplicates. …”

Table_1_Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy.XLSX by Yufei Chen (206648)

“…Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. …”

Computational Investigation of the Lewis Acidity in Three-Dimensional and Corresponding Two-Dimensional Zeolites: UTL vs IPC-1P by Ho Viet Thang (1755028)

“…The adsorption and catalytic properties of three-dimensional zeolite UTL were investigated computationally along with properties of its two-dimensional analogue IPC-1P that can be obtained from UTL by a removal of D4R units. Adsorption properties and Lewis acidity of extra-framework Li⁺ sites were investigated for both two- and three-dimensional forms of UTL using the carbon monoxide as a probe molecule. …”

The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance <i>In Vitro</i> and <i>In Vivo</i> Derived from Human Breast MCF-7/ADR Cells by Long Wu (655081)

“…Multidrug resistance reversal by 3-Bromopyruvate occurred through at least three approaches, namely, a decrease in the intracellular level of ATP and HK-II bioactivity, the inhibition of ATPase activity, and the slight decrease in P-glycoprotein expression in MCF-7/ADR cells.…”

TRPV4 mediated calcium influx after stretch. by N. Pairet (5109128)

“…(B) Summary of the mean % Ca²⁺ response from the 60 sec after stretch, a 2.5 fold increase in the [Ca2+]_i was observed that was significantly decreased by 26% with the TRPV4 antagonist (1 <b>μ</b>M) GSK2193874 (184.5 ± 5.07 vs 248.6 ± 10.17). …”

Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Lifespan was measured in three replicates comprising an average of 103 worms per condition. Data is presented as mean lifespan (columns 1–4), change mean lifespan in comparison to an empty vector RNAi control (column 5), or as the change in the extension of lifespan induced by each long-lived mutant (columns 6–8; for clarity, only decreases >15% are shown). …”