Placenta-Enriched LincRNAs <i>MIR503HG</i> and <i>LINC00629</i> Decrease Migration and Invasion Potential of JEG-3 Cell Line by Bruna Rodrigues Muys (2588305)

“…Further analysis, using a cancer cell lines panel, showed that <i>MIR503HG and LINC00629</i> were expressed in 50% and 100% of the cancer cell lines, respectively. …”

Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: <i>In vitro</i>, kinetic, and <i>in silico</i> studies... by Sumaira Javaid (7886897)

Representative experimental samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Mechanical testing apparatus and samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Relationship between UCS, E, and water content. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Hygroscopic experimental device. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Robustness of results. by Raimundo Atal (18272064)

Simultaneous silencing of isoamylases ISA1, ISA2 and ISA3 by multi-target RNAi in potato tubers leads to decreased starch content and an early sprouting phenotype by Stephanus J. Ferreira (4249219)

Effect of anti-miR-146a LNA or miR-146a mimic upon IL-1β-induced release of inflammatory molecules. by Anand Iyer (135705)

“…Data are expressed relative to unstimulated control cells (mean ± SEM from three separate experiments). In comparison with IL-1ß alone, cultures stimulated with IL-1ß and transfected with LNA-anti miR-146a exhibited significant increase of IL-6 and IP-10 release, whereas transfection of glial cells with miR-146a mimic significantly decreased the levels of IL-6, IL-8, G-CSF, IFN-γ, IP-10, MIP-1β, and TNF-α (* p<0.05). …”

Variations in the prevalence of episiotomy in France between 2010 and 2021 according to the classification for episiotomy practices. by Raphaele Houlbracq (20558509)

Decreased of downstream signalling protein phosphorylation and intracellular TNF-α production in GM-CSF treated CD14⁺ cells upon TLR ligand induction. by Kambis Sadeghi (3190407)

Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine Cytidylyltransferase by Lívia Marton (756117)

“…The CHO-MT58 cell line expresses a mutant variant of CCT, and displays a thermo-sensitive phenotype. …”

Sexual maturity status of female C57BL/6J Mice at different ages. by Yan She (8639796)

Astragaloside IV reduced oxidative stress in SH-SY5Y cells and decreased iNOS expression in BV-2 cells upon IFNγ stimulation. by Yixin He (466799)

Supplementary Data S2 from SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance by Kristen Jensen-Pergakes (15090247)

HbA1c, BMI and Lipid levels of study participants (n = 382). by Habiba I. Ali (10451382)

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”

Induction of histones H3 and H4 hyper-acetylation and decreased histone H3-lys27 trimethylation follow GBM cell line treatment with HYP. by Naama Dror (459005)

Estimates of the differencing parameter, d, in Eq (1). by Luis Alberiko Gil-Alana (14659817)