Microtubule inhibitors cause cell cycle arrest and induce RKIP expression. by Saad Yousuf (541082)

“…Cells were harvested and washed twice with PBS and whole cell lysates were prepared for Western blot analysis as we have previously reported <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092478#pone.0092478-AlMulla1" target="_blank">[28]</a>. …”

Mast cell activation occurs at 3 days of cuprizone administration. by John Shelestak (8490477)

“…(B-C) Quantification of mast cell presence shows significant increases in both cortical and corpus callosum tissue after 3 days of cuprizone administration. (mean ± s.e.m.). <i>n</i> = 6 (D-E) Measures of mast cell degranulation shows a decrease in stained mast cell granules in both cortical and corpus callosum tissue after 3 days of cuprizone administration. …”

Th17 level is higher in severe and poor-responder patients, Treg level is higher in responder patients. by Takuya Furuhashi (276955)

“…Horizontal bar indicates mean value. (<b>B</b>) Psoriasis patients were grouped in each treatment group achieving 50%, 75% improvement PASI score from baseline (PASI 50, PASI 75). …”

PEDro scores of included studies. by Flor Isela Torres-Rojo (22097369)

“…The effect of vigorous interventions showed an increase in antioxidants (Z=2.44, I²=67%, p=0.01) and a decrease in oxidants (Z=5.44, I²=0%, p<0.00001), while in non-vigorous exercise, no significant differences were observed in redox status.…”

DataSheet_1_The short-term and long-term effects of intranasal mesenchymal stem cell administration to noninflamed mice lung.pdf by Marlena Tynecka (13807786)

Renal lipids and inflammatory changes in kidney of HPRT^-/- treated mice. by Cristina Zennaro (424123)

“…The WT tissue is completely negative, whereas kidneys from HPRT^-/- mice show numerous positive areas in the interstitium, mainly within and around the lumen of dilated tubules. Scale bars = 50 μm. (b) Gene expression analysis of adipogenesis-related molecules C-EBP alpha and beta and PPAR alpha and gamma shows no differences based on the genotype in vehicle-treated mice, whereas a significant increase of C-EBP alpha and beta and a significant decrease of PPAR alpha are detected in allopurinol-treated HPRT^-/- animals. …”

Apamin-induced alterations in J774 1.6 macrophage metabolism by T. Picoli (6936461)

“…Therefore, all analyzed concentrations (1.25 to 10μg/mL) decreased mMP. Such decrease in apoptosis might be due to a suppression of mitochondrial pro-apoptotic messengers, as this peptide causes no oxidative stress, lipid peroxidation, and DNA damage. …”

Lats2 inhibits Wnt signaling. by Yang An (326217)

“…<p>(A) The protein levels of p-DVL2, β-catenin and Wnt signaling targets decrease during adipocyte differentiation. …”

Potential Impacts of Climatic Change on European Breeding Birds by Brian Huntley (38285)

“…Even if potential range changes were realised, the average number of species breeding per 50×50 km grid square would decrease by 6·8–23·2%. …”

Relative changes in cytokines present in the circulation 30 and 60 days after irradiation. by Marek Lenarczyk (11483998)

“…Rats were six months of age at the time of irradiation or sham-irradiation. Data shown are mean <u>+</u> SD, <i>n</i> = 5-12/group. * denotes a significantly increase and * denotes a significant decrease in cytokine levels relative to sham-irradiated aged-matched controls.…”

Different simulation protocols of increased firing and depressed activity. by Isabelle Ayumi Spühler (444465)

“…After 4 sec, 50% of release sites increase or decrease their release for a short time window to simulate phasic firing of the dopaminergic neurons. …”

Sensitivity of biomass and cumulative harvest to magnitude of climate impacts under alternative management strategies. by Jameal F. Samhouri (10136090)

“…<p>Outcomes of implementing fixed versus annual climate adaptive harvest management strategies on mean population biomass and cumulative harvest over 50-year simulations in a population subject to a gradual decrease or increase in carrying capacity <b>(a, d)</b>, productivity <b>(b, e)</b>, and both carrying capacity and productivity <b>(c, f)</b>. …”

Color space representation across different CNN layers and different CNN architectures. by JohnMark Taylor (8329326)

“…The averaged correlation over all objects for each layer is plotted in a line graph on the right of each scenario. In the first scenario, the color space structure within each object differs substantially across processing, resulting in a large decrease in correlation across layers. …”

Optical coherence tomography angiography findings in malignant hypertensive retinopathy by Berna Dogan (5762903)

“…Visual acuity was 20/63 in the right eye and 20/50 in the left eye. Fundus examination revealed signs of hypertensive retinopathy; thus, a multidisciplinary approach was adopted for the diagnosis and treatment of this patient. …”

Sensitivity analysis. by Wei Zhang (405)

“…The FM/RME treatment group presented a greater decrease in SNB than the untreated controls (MD = -2.70, 95% CI = -3.34–-2.05, P < 0.00001). 3: Angle ANB. …”

Birds in Anthropogenic Landscapes: The Responses of Ecological Groups to Forest Loss in the Brazilian Atlantic Forest by José Carlos Morante-Filho (756360)

“…At each site, we sampled birds using the point-count method. We used a null model, a generalized linear model and a four-parameter logistic model to evaluate the relationship between richness and abundance of the bird groups and the native forest amount. …”

Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice by Janeen H. Trembley (644906)

“…The sub-50 nm size TBG nanocapsule (s50-TBG) is a slightly negatively charged, uniform particle of 15 - 20 nm size which confers protection to the nucleic acid cargo. …”

The hARD1 NLS mutant suppresses cell proliferation. by Ji-Hyeon Park (554738)

“…Arrows indicate cells with altered morphology (black, enlarged; red, rounded). Scale bar, 50 µm. <b>B</b> and <b>C</b>. hARD1ΔN-expressing cells showed a marked decrease in cell growth. …”

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27 by Yohann Bernard (198579)

“…Administration of our lead compound (FL3) to mice attenuated cardiomyocyte apoptosis and cardiac fibrosis, as reflected by a 50% decrease of mortality.</p> <h3>Conclusions/Significance</h3><p>These results suggest a prophylactic potential of flavaglines to prevent doxorubicin-induced cardiac toxicity.…”

The effect of stretch on the MAP of the fish heart. by Simon M. Patrick (364948)

“…MAPD is shown at MAPD25 (A,D), MAPD50 (B,E) and MAPD90 (C,F) (mean ± S.E.M, <i>p</i><0.05). …”