VpsO-503 does not undergo tyrosine trans autophosphorylation <i>in vitro</i>. by Carmen Schwechheimer (9300303)

“…The lack of a second band at a slower migration indicates that we did not observe <i>in trans</i> phosphorylation on the C-terminal tail of the GST-fusion VpsO-503^K551A (catalytically inactive) mutant by the VpsO-503 WT enzyme. …”

Proliferation of CTS-treated cells. by Rebecca J. Clifford (497197)

“…<p>A) Normal MCF10A cells exhibited a concentration-dependent decrease in BrdU incorporation (proliferation) when treated with 500 nM ouabain, 50 nM bufalin or 100 nM bufalin for 2 hours (p<0.01). …”

Knockdown of IRAK1 and TRAF6 increases SAS cell oncogenicity. by Pei-Shi Hung (489732)

Estimating the impact of city-wide <i>Aedes aegypti</i> population control: An observational study in Iquitos, Peru by Robert C. Reiner Jr. (736298)

“…We found that with complete neighborhood coverage MoH intra-domicile space spray would decrease <i>Ae</i>. …”

BX-C genes control DT tube tapering. by Ryo Matsuda (685668)

“…This could be attributed to competition between the overexpressed proteins and endogenous <i>abdA</i> or <i>AbdB</i> [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004929#pgen.1004929.ref046" target="_blank">46</a>], leading to a systemic decrease of tube diameter.…”

Learning differently modulated sensory responses of RS and FS neurons in wM1 and wM2 areas. by Vahid Esmaeili (12700352)

“…<p><b>(A)</b> Decrease of whisker response in wM1 RS neurons across learning. …”

Expression of <i>FMRFaR</i>^<i>RNAi</i> in dopaminergic neurons reduces membrane depolarization. by Preethi Ravi (5634665)

“…(D) Representative images of neuronal depolarization as observed by a decrease in Arclight fluorescence in the same genotypes shown in (A). …”

Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance - Fig 7 by Helen E. McNeil (8190873)

“…Data presented are the mean of three independent biological replicates and are shown as the time taken for the fluorescence to decrease by 50% +/- SE. …”

Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423 by Tomoko Kashiyama (162572)

“…In mouse xenograft models, DS-7423 suppressed the tumor growth of OCCA in a dose-dependent manner. Flow cytometry analysis revealed a decrease in S-phase cell populations in all the cell lines and an increase in sub-G1 cell populations following treatment with DS-7423 in six of the nine OCCA cell lines tested. …”

Data_Sheet_1_Biological Characterization of Hepatitis B virus Genotypes: Their Role in Viral Replication and Antigen Expression.docx by María Mercedes Elizalde (5184335)

“…Genotype A2 expressed the lowest pgRNA levels, with a 70-fold decrease in relation to the other genotypes (p<0.0001), while genotype B2 showed the lowest Precore RNA levels, with a 100-fold reduction compared to genotype A2 (p<0.0001). …”

Antigen B from <i>Echinococcus granulosus</i> enters mammalian cells by endocytic pathways by Edileuza Danieli da Silva (5176148)

“…AgB uptake was observed in four different cell lines, NIH-3T3, A549, J774 and RH. Inhibition of caveolae/raft-mediated endocytosis causes about 50 and 69% decrease in AgB internalization by RH and A549 cells, respectively. …”

Spiking activity of dentate gyrus granule cells during exploratory behaviour evokes large short-term plasticity at mossy fiber synapses <i>in vitro</i>. by Anja Gundlfinger (366062)

“…A large dynamic range of response amplitudes is apparent with amplitudes generally largest with ISIs ranging from 50–1000 ms. …”

Generation of post-mitotic neurons requires NRG1-II. by Tomomi Sato (301255)

“…<i>4neurog1</i>:<i>nRFP</i>) at 50 hpf. Scale bar, 10 μm. <b>C</b>. Quantification of <i>neurod</i>:EGFP intensity in the OT for the experiment shown in A (mean ± s.e.m.; **<i>P</i> < 0.01; n = 4 per group). …”

Characterizing suboptimal child passenger safety practices in crashes with fatalities: Child, driver, vehicle, neighborhood, and policy factors by Arthi S. Kozhumam (14176683)

“…We sought to identify child, driver, vehicle, neighborhood, and policy-level factors associated with suboptimal child passenger safety practices in motor vehicle collisions (MVCs) with a fatality. …”

Acid gradient created by glucose metabolism promotesphosphate bond synthesis. by Gautam Dhar (723875)

“…<p>(A) Schematic showing the steps followed to analyze the role of acid gradient in phosphate bond synthesis during glucose metabolism in cancer. …”

Responses to growth factors. by Kazunari Mouri (265029)

Smad1 target genes repressed and activated in senescence. by Atsushi Kaneda (198186)

“…<p>(<i>A</i>) Repression of Smad1 target genes by H3K27me3. 838 Smad1 target genes in MEF were sorted by fold expression change between MEFp2 and mean of RasV12 day3, 7, and 10 (<i>Expression column</i>). 50 genes showed increase of H3K27me3 reads in RasV12 by 0.4 or more (↑<i>column</i>), and were significantly enriched downward (*P = 0.004, Kolmogorov-Smirnov test), i.e. repressed. …”

Response kinetics and relationship to Weber’s law in the m1 controller (Fig 3). by Jonas V. Grini (15374504)

“…<p>The set-point of <i>A</i> is 3.0. (a) Step-wise increase of <i>k</i>₂ from 1.0 to 5.0 at time <i>t</i>=10 at different but constant backgrounds <i>k</i>₄ (0–128.0, phases 1 and 2). …”

Video1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.AVI by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”

DataSheet1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.docx by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”