<i>Otx</i> knockdown causes a decrease in <i>dct</i> expression in the developing RPE. by Brandon M. Lane (123574)

“…<i>dct</i> expression was reduced only in the ventral most region of the optic cup in single morphants (B–D, white arrows) compared to controls (A). <i>dct</i> expression was significantly decreased in the ventral RPE of <i>otx1a</i>/<i>otx2</i> morphants and to an even greater degree in <i>otx1a</i>/<i>otx1b</i>/<i>otx2</i> morphants (E–F, white arrows). …”

Image3_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

“…BCA treatment shortened Ri from ∼23 h observed in vehicle-treated mice to ∼5.5 h, associated with an increase in apoptotic events and efferocytosis, both key steps for the resolution of inflammation. These effects of BCA were prevented by H89, an inhibitor of protein kinase A (PKA) and G15, a selective G protein–coupled receptor 30 (GPR30) antagonist. …”

Image2_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

“…BCA treatment shortened Ri from ∼23 h observed in vehicle-treated mice to ∼5.5 h, associated with an increase in apoptotic events and efferocytosis, both key steps for the resolution of inflammation. These effects of BCA were prevented by H89, an inhibitor of protein kinase A (PKA) and G15, a selective G protein–coupled receptor 30 (GPR30) antagonist. …”

Image4_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

“…BCA treatment shortened Ri from ∼23 h observed in vehicle-treated mice to ∼5.5 h, associated with an increase in apoptotic events and efferocytosis, both key steps for the resolution of inflammation. These effects of BCA were prevented by H89, an inhibitor of protein kinase A (PKA) and G15, a selective G protein–coupled receptor 30 (GPR30) antagonist. …”

Image1_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

“…BCA treatment shortened Ri from ∼23 h observed in vehicle-treated mice to ∼5.5 h, associated with an increase in apoptotic events and efferocytosis, both key steps for the resolution of inflammation. These effects of BCA were prevented by H89, an inhibitor of protein kinase A (PKA) and G15, a selective G protein–coupled receptor 30 (GPR30) antagonist. …”

Anti-IAV activity of rhein in mice. by Qian-Wen Wang (3467420)

Glutamate-induced dendritic retraction visualized in CMFDA-stained neurons. by María Fernanda Podestá (639243)

Early surface PSA-NCAM reduction induced by glutamate exposure. by María Fernanda Podestá (639243)

“…(B) Quantification of PSA-NCAM immunoreactive area showed decreased levels at neuronal surface 3 h after glutamate exposure, which remained low for the rest of the studied period (3–6 h). …”

PRV and HSV-1 employ US3 to decrease Bclaf1 in a proteasome-dependent manner. by Chao Qin (119135)

Time-course of changes induced on NCAM and SYN synaptic patterns and levels by glutamate exposure. by María Fernanda Podestá (639243)

“…<p>Hippocampal neurons in culture (DIV 12–13) were briefly exposed to 5 µM glutamate and evaluated 1, 3, 6 and 12 h later. (A) Microphotographs of hippocampal neurons in culture doubled stained for NCAM and SYN. …”

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

“…Compound <b>19</b> displays antitumor activity in an AML tumor model and was also shown to decrease Foxp3 transcript levels in a dose dependent manner.…”

SRC-3 treatment decreased tumor growth in a Jeko-1 ibrutinib resistant mouse model. by Imani Bijou (18275174)

Eggs jointly coordinate a caspase-1 and caspase-8 dependent pyroptotic cell death. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

Effect of LUX and IB on LYN and CD79A in SU-DHL-6 cells. by Himangshu Sonowal (14761882)

Maternal consumption of green tea extract during pregnancy and lactation alters offspring's metabolism in rats - Fig 4 by Ana C. L. Hachul (5533091)

Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene by Muhammad Idrees (92773)

Glutamate exposure reduces MAP-2 immunostaining and induces changes in synaptic markers and cell adhesion molecule NCAM in the absence of neuronal death. by María Fernanda Podestá (639243)

“…PSA-NCAM immunoreactive area drastically decreased. Results are expressed as mean values (±SEM) of 20-30 neurons or 10 microscope fields (280,000 µm²/FOV) per experimental condition. …”

Regression Results for Average Antibiotic Resistance. by Peter Collignon (704972)

Decreased Bone Mineral Density Is an Independent Predictor for the Development of Atherosclerosis: A Systematic Review and Meta-Analysis by Chenyi Ye (2697208)

HemaMax administration decreased leukopenia (a) and thrombocytopenia (b) at nadir in irradiated, unsupported rhesus monkeys. by Lena A. Basile (331369)