Knockdown of <i>CPSF6</i> leads to global shifts in PAS usage as well as major transcript and protein abundance changes. by Christoph Schmal (395936)

“…(<b>G</b>) Representative examples that show a decrease (<i>SHISA2</i>, top) or increase (<i>HIPK1</i>, bottom) of transcript abundance upon <i>CPSF6</i> knockdown. …”

Microtubule inhibitors cause cell cycle arrest and induce RKIP expression. by Saad Yousuf (541082)

“…Analysis for apoptosis was performed using a FACSCalibur flow cytometer (Data represents the mean ± S.D., of 2 independent experiments performed in duplicate). …”

Nef Targets ABCA1-Dependent Cholesterol Efflux by Zahedi Mujawar (379543)

<i>S</i>. <i>pneumoniae</i> RNA regulators are ligand responsive and most designed mutations function as anticipated. by Indu Warrier (581139)

“…Bar height indicates the mean replicate value, error bars indicate standard error of the mean, individual points shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011188#pgen.1011188.s009" target="_blank">S2 Fig</a>. …”

Possible effects of estrogens deprivation and aging on inflammation and endothelial damage at menopause. by Nicté Figueroa-Vega (741283)

“…<p>When estrogens decline and during old age, important changes occur in the endothelium: first, estrogen decrease, leads a low NO bioavailability inducing destabilization of endothelial cells, favoring up-regulation of adhesion molecules. …”

[Ca²⁺] dynamics comparison between WT network and blocking an individual NFA-sensitive channel. by Jesús Espinal-Enríquez (622164)

“…Concentration units are arbitrary, they comply with the above restrictions and are set for comparative purposes, time is measured by simulation steps and frequency refers to the fraction of a cycle covered by a simulation step, i.e cycles per simulation step. …”

Ca2+-dependent release of ATP can be evoked in the cortical astrocytes of the wild-type but not of the dn-SNARE mice. by The PLOS Biology Staff (614265)

“…(C) Elevation of the Ca2+ level in any of the dn-SNARE astrocytes did not lead to activation of phasic purinergic currents in the sniffer cell. Inlays in (A–C) show examples of individual phasic currents recorded at moments indicated; scale bars are 50 ms and 10 pA. …”

Representative results of integrate-and-fire simulations for different learning rules. by Kendra S. Burbank (180062)

“…The simulations in <b>b–d</b> were classified as having “extreme weights” meaning that >50% of the weights were either at 0 or at the weight boundaries (±50). …”

Organ level model. by Shayoni Ray (179927)

“…<p>An organ-level simulation containing three ideally localized clefts is shown at (a) 0 MCS and (b) 1500 MCS (Scale = 50 µm). The results were quantified with (c) cleft depth and (d) spanning angle. …”

Economic evaluation of an active search system to monitor the outcomes of health-related claims by Nayara Luiza Pereira Rodrigues (8303202)

“…Results: The advisory service promoted a decrease of 40% (p=0.01) in lawsuits. There was a 31% reduction in court costs (p=0.003), with medicines accounting for 33% of this amount. …”

Reusable Homogeneous Catalytic System for Hydrogen Production from Methanol and Water by Peng Hu (196664)

“…The catalyst solution can be reused without isolation and purification, with no decrease in catalytic activity being observed for a period of ∼1 month. …”

Cerebellar cortex of SCA3 patients. by Tzu-Yun Wang (427574)

Cerebral cortex of SCA3 patients. by Tzu-Yun Wang (427574)

Untargeted <i>In Vitro</i> Metabolomics data from <i>Burkholderia cenocepacia </i>J2315, H111 and <i>Staphylococcus aureus </i>NRS77 Biofilm Supernatant by Hayden Skaggs (20833868)

“…Thresholds were set as spectral similarity ≥ 0.4, retention time difference ≤ 0.15 and m/z variation window ≤ 5 ppm. 2D LC-MS/MS data without a match with the metabolites in the proprietary database were further analyzed using Compound Discoverer software (v 2.0, Thermo Fisher Scientific, Germany), where MS/MS spectra similarity score threshold was set ≥ 40 with a maximum score of 100. …”

Image_3_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)

Image_1_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)

Image_4_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)

Image_2_The Streptomyces coelicolor Small ORF trpM Stimulates Growth and Morphological Development and Exerts Opposite Effects on Actinorhodin and Calcium-Dependent Antibiotic Prod... by Alberto Vassallo (8466042)

Effect of T/HS without or with IL-6 treatment on the liver inflammation transcriptome; impact of Stat3 inhibition on the IL-6 effect. by Ana Moran (80716)

“…In <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021449#pone-0021449-g004" target="_blank">Figure 4B</a>, the 235 inflammation transcriptome genes whose expression levels were changed in SBR50 vs. sham were separated into those genes whose transcript levels were increased in SBR50 vs. sham (126 genes; left side of panel) and those whose transcript levels were decreased in SBR50 vs. sham (109 genes; right side of the panel). …”

DataSheet_1_Irrigation with primary wastewater alters wood anatomy and composition in willow Salix miyabeana SX67.docx by Ahmed Jerbi (14708509)

“…Compared to unirrigated plants (UI), stem sections of plants irrigated with primary wastewater (WWD) showed an unexpected decrease of hydraulic conductance (K_S) associated with a decrease in vessel density but not vessel diameter. …”