GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

Subjects:

S1 Dataset - by Nelmo Jordão Manjate (16324619)

Subjects:

Postnatal decrease in PV+ cortical interneurons in Fgfr1 mutant mice. by Karen Müller Smith (613941)

“…Scale bar is 50 µm in <b>A</b>,<b>B</b>. Stereological analysis show significant decreases in in both GFP and PV immunopositive cells in Fgfr1 mutant mice as compared to littermate controls (<b>C</b>). …”

ATA and AH decrease the abundance of viruses released by infected MDCK cells. by Anwar M. Hashem (281354)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

The initiation region/matrix attachment region (IR/MAR) increased the homogeneously staining region (HSR) elongation rate and decreased the frequency of micronuclei after elevation... by Shun-suke Tanaka (604228)

<i>B-MOBILE</i> - A Smartphone-Based Intervention to Reduce Sedentary Time in Overweight/Obese Individuals: A Within-Subjects Experimental Trial by Dale S. Bond (588506)

“…However, few sedentary-reducing interventions exist and none have utilized smartphones to automate behavioral strategies to decrease SED. We tested a smartphone-based intervention to monitor and decrease SED in overweight/obese individuals, and compared 3 approaches to prompting physical activity (PA) breaks and delivering feedback on SED.…”

Conditions that ablate cytonemes decrease signaling, reduce myoblast and tumor growth. by Sol Fereres (664350)

PRL decreases anterior pituitary cell proliferation <i>in vivo</i>. by Jimena Ferraris (314722)

Combined EGCG/As decreases the viability of two types of EC, HUVEC and HBMEC. by Jee-Youn Kim (796526)

The number of motor neurons is decreased in old Gas7-deficient mice. by Bo-Tsang Huang (162584)

Substitution of a lysine residue at position 8 of two model 9mer H2-K^b epitope precursors leads to a marked decrease of N-terminus trimming by ERAP1 <i>in vitro</i>. by Irini Evnouchidou (375919)

“…<p><i>Panels </i><i>A</i><i> and </i><i>B</i>, peptides LSIINFEKL and the variant LSIINFEAL (both at 50 µM) were incubated with 7.8 nM of ERAP1 for 1 hr at 37°C and the products analyzed by RP-HPLC. …”

FLZ decreased the expression of BACE1 and did not affect the expression of IDE. by Xiu-Qi Bao (479278)

Inflammatory cell infiltration in infected tissue is decreased in the AG treated group. by Mario C. Salinas-Carmona (9553084)

The estrogen receptor-α agonist PPT decreases cardiac myofilament activation. by Justyna Kulpa (313372)

“…Untreated controls showed no differences at any time, and are combined as a single group in each graph (N = 23). Maximum actomyosin MgATPase activity tended to decrease following PPT treatment, but did not reach statistical significance. …”

Silencing JARID1B decreases epithelial to mesenchymal transition (EMT). by Yung-Ting Kuo (736349)

The effect of transcription inhibition on UV sensitivity is decreased after serum starvation. by Ivaylo Stoimenov (222016)

Summary of the gradual disappearance of the peaks with decreasing DMSO-d6 concentrations. by Swagata Chakraborty (188090)

“…<p>(<b>A</b>) ¹H-¹⁵N HSQC spectra of GED in 100%, 90%, 85%, 80%, 70% and 50% DMSO-d6 at 45°C, as marked in the left hand panel within the spectra. …”

Decreased number of cones and retinal ganglion cells in Oc-deficient retina. by Michaela Kreplova (9239560)

Loss of Trib2 decreases disease latency of Notch-driven T-ALL. by Sarah J. Stein (3168600)

“…Mice with a body condition score of ≤2 and decreased mobility were euthanized (n = 8 Trib2^+/+ and n = 12 Trib2^-/- recipients. …”