Toxins from the Caribbean sea anemone Bunodeopsis globulifera increase cisplatin-induced cytotoxicity of lung adenocarcinoma cells by Heidi I Monroy-Estrada (5669477)

“…Results Pre-exposure to CV, F1 and F2 fractions increases cisplatin cytotoxicity in human lung adenocarcinoma cells under specific conditions. Exposure to CV at 50 μgmL-1 induced a reduction of approximately 50% in cell viability, while a similar cytotoxic effect was observed when cell culture was exposed to F1 at 25 μgmL -1 or F2 at 50 μgmL-1. …”

Table1_Retrospective Recall of Psychological Distress Experienced During the First COVID-19 Lockdown in Italy: Results From the ALT RISCOVID-19 Survey.doc by Francesca Bracone (12014342)

“…</p><p>Methods: Cross-sectional analysis on 1,880 adults (mean age 48.9 ± 14.5 years) from the web-based ALT RISCOVID-19 survey. …”

Metabolomic and chemogenomic profiling. by Wesley C. Van Voorhis (191219)

“…Six of seven compounds (indicated in red) reported to target <i>Pf</i>ATP4 [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005763#ppat.1005763.ref025" target="_blank">25</a>] showed a distinct metabolic response characterized by the accumulation of dNTPs and a decrease in hemoglobin-derived peptides. …”

Lovastatin in combination with VEGFR-2 TKIs inhibits ligand induced activation of AKT, S6K1 and 4EBP1. by Tong T. Zhao (361937)

“…All cells were then lysed after stimulation with 50 ng/ml VEGF₁₆₅ for 30 min. Results demonstrated that lovastatin in combination with KRN633 induced the most significant decrease in phosphorylation status of all three proteins in H28 cells. …”

The impact of outcome perceptibility on the precision of the estimate of the differential effect of treatment. by Ognjen Arandjelović (295373)

Results of Multivariate Regression Analyses. by Jeet Gandhi (262339)

“…The association coefficient is −0.07, which means after adjusting for <i>EGFR</i> mutation and <i>HER2</i> copy number effects, the IC50 will decrease 0.85 fold when <i>EGFR</i> relative copy number increases 1 unit.…”

Ivermectin and albendazole withdrawal period in goat milk by Patrícia Silva Santos (6305066)

“…The amount of residues contained in themilk was decreasing in function of time. The mean daily rates of decrease of albendazole residues were 63.34%, 40.18 and 100.0%, from the 2ndto the 4thday, respectively; on the 3rdday after treatment, 50% of the samples showed concentrations ≥ 47.61 μg.mL–1, and on the 4thday, no sample had albendazole residue. …”

Isomeric Mono-, Di-, and Tri-Bromobenzo-1H-Triazoles as Inhibitors of Human Protein Kinase CK2α by Romualda Wąsik (119538)

“…The decrease in pK_a on halogenation of the peripheral C(4)/C(7) atoms virtually nullifies the gain due to hydrophobic interactions, and does not lead to a decrease in IC₅₀. …”

Effects of Herbicides on the Survival of the Brazilian Native Bee Melipona scutellaris Latreille, 1811 (Hymenoptera: Apidae) by R.C.F. NOCELLI (8075633)

Probing the auditory nerve using round-window response in control and ouabain-poisoned cochleae. by Charlène Batrel (3639406)

“…<p><b>(A, B)</b> Iso-level neural index in control (<b>A</b>, <i>n</i> = 10 gerbils) and ouabain-poisoned cochleae (<b>B</b>, <i>n</i> = 9 gerbils). …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”

Knockdown of miR-214 inhibits tumor growth in nude mice: <i>in vivo</i> functional studies. by Zi-Chen Zhang (511377)

Anchusa italica extract: phytochemical and neuroprotective evaluation on global cerebral ischemia and reperfusion by Akram Torki (5383154)

“…Induction of ischemia/reperfusion caused a decrease in the antioxidant capacity of the brain and serum as well as an increase in the malondialdehyde of the brain and serum. …”

Image_1_Effects of Antimony on Rice Growth and Its Existing Forms in Rice Under Arbuscular Mycorrhizal Fungi Environment.TIF by Min Zhou (173135)

Necroptosis sensitivity screen in 941 cancer cell lines identifies drivers of necroptosis resistance. by Ayaz Najafov (322631)

“…Note that RIPK1, RIPK3, and MLKL levels decrease in lane 2 because of induction of necroptosis, formation of amyloid-like necrosome structure, and translocation of these proteins into a detergent-insoluble fraction. …”

Reduced mitochondrial membrane potential (ΔΨ_m) in <i>DJ-1</i>−/− MEFs. by Emilie Giaime (316501)

“…<p>(<b>A, B</b>) Confocal microscopic analysis. (<b>A</b>) Representative confocal microscopic images of <i>DJ-1</i>−/− and +/+ MEFs after staining with TMRM (50 nM, red) and Mitotracker Green (200 nM) in the presence or absence of oligomycin (Olig, 1 µM) or FCCP (10 µM). …”

The expression of α7^GFP changes during different developmental stages of tooth development. by Scott W. Rogers (271631)

“…H) By P12, ∼2days prior to eruption, the molar enamel is essentially complete and ameloblasts (ab) are degenerating and there is a coincident decrease in intensity of the α7^GFP signal. …”

Cytotoxicity of candidate agents to cholangiocarcinoma cells. by Chiara Braconi (235041)

“…All three compounds decreased cell viability in a concentration-dependent manner, with an IC50 for felodipine of 26±5 µM, nitrendipine, 44±10 µM and nifedipine, 15±4 µM. …”

FBW7 is degraded during <i>E</i>. <i>chaffeensis</i> infection. by Jennifer Y. Wang (8787527)

“…By day 2 pi, FBW7 levels decreased ~50% and ~70%, respectively compared to uninfected controls. …”

Ongoing LFP activity in V1 and subiculum during continuous change of anesthesia level. by Rüdiger Land (297646)

“…<p>(A) Reconstruction of electrode site location. Upper electrode sites are located in V1 (gray dots) and lower sites in subiculum (white dots). …”