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16581
Binding and activity of TM fusion proteins on mouse endothelial cells.
Published 2013“…(d) Antibody blockade of EPCR results in a ∼50% decrease in APC generation by endogenous TM and anti-ICAM scFv/TM, but not anti-PECAM scFv/TM. …”
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16582
Aflatoxin B<sub>1</sub> exposure down-regulates β-catenin expression in hepatoma carcinoma cell.
Published 2013“…(C) β-catenin protein levels are decrease in Chang liver and HepG2 cells treated with AFB<sub>1</sub> at their IC<sub>50</sub> value. …”
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16583
Overlay diagram of the flow cytometric histograms representing respiratory active and inactive <i>E.</i>
Published 2013“…Compared to the active control, ETEC exposed to glycine and sarcosine (50 mM, pH 9.5) showed a significant decrease in MFI after 15 min of incubation (p = 0.017 and p = 0.008, respectively). …”
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16584
Exemplar press-related channel.
Published 2019“…Mean firing rates show a complex task response with firing rates significantly (p<0.05) decreased around the lever press and 650 ms prior to the reach to the pellet and then significantly increased immediately prior to the reach to the pellet. …”
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16585
<i>Apoe</i> expression is reduced in the parietal cortex and CA1 of aged mice.
Published 2015“…(B) Quantification of <i>Apoe</i> hybridized area in the cortex shows a significant decrease of <i>Apoe</i> expression in the aged mice. …”
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16586
Effect of TAK-242 on LPS-induced inhibition of myogenesis.
Published 2017“…(B) TAK-242 partially reversed the LPS-induced decrease in myogenic index. Cells were treated as described in (A). …”
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16587
Single-leg stance center of pressure velocity.
Published 2023“…Both groups showed a decrease in CoP velocity in the medio-lateral and anterior-posterior direction. …”
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16588
Effect of TLE1 overexpression in the developing chick ventral spinal cord.
Published 2012“…Data are expressed as mean ± SEM (*<i>p</i><0.05). Scale bars = 50 µm.</p>…”
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16589
EGF enhances cyclin G2 degradation.
Published 2017“…A dose-dependent decrease of cyclin G2 stability was also observed. …”
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16590
Nilotinib binds to SMO and competes with Cyclopamine and SAG.
Published 2019“…Data represent the mean and standard deviation for two independent experiments, max GMFI: Maximum Geometric Mean Fluorescence Intensity; UT: Untransfected HEK293T cells (<b>c)</b> Concentration response curve of SAG in the Gli-Luciferase functional assay in the absence or presence of inhibitors: Nilotinib or Vismodegib shifted EC<sub>50</sub> of SAG to the right without decrease in maximal response, suggesting a competitive relationship. …”
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16591
<i>S</i>. <i>pneumoniae</i> RNA regulators are ligand responsive and most designed mutations function as anticipated.
Published 2024“…<p><b>(A)</b> β-galactosidase activity of RNA reporter strains grown in the absence and presence of ligand or ligand precursor (0.3 μg/mL thiamine, 140 ng/mL riboflavin, 20 μg/mL uracil, 75 μg/mL glycine, 204 μg/mL tryptophan, 50 μg/mL guanine) demonstrates regulation of gene expression with a significant difference between expression in the two conditions. …”
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16592
Soy isoflavones genistein and daidzein protect primary cortical cultures from Tat neurotoxicity.
Published 2013“…Data represents mean values ± SEM, n of cultures analyzed = 7–12 per each group. *- indicates significant (<i>p</i>≤0.05) protective effects of the selected compounds against Tat neurotoxicity (cell viability decrease) in cortical cell cultures. …”
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16593
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16594
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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16595
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16596
Use of GPCR-HIT to show effect of AT<sub>1</sub> receptor activation on CCR2/Gα<sub>i1</sub> proximity.
Published 2015“…It has been observed previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref039" target="_blank">39</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref041" target="_blank">41</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref042" target="_blank">42</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref044" target="_blank">44</a>] that the BRET signal can increase or decrease as a consequence of the ligand-induced conformational change associated with Gα<sub>i1</sub> protein activation (A). …”
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16597
Cellular blebbing in U373MG cells induced by NK1R activation is mediated by the Rho/ROCK/MLCK pathway.
Published 2011“…<p>(<b>A</b>) Representative cell impedance recordings of U373MG cells preincubated with control, 2.0 µg/ml C3 transferase, 10 µM Y27632 or 50 µM ML9 for 60 min and then stimulated with SP (100 nM) where indicated by <i>solid arrow</i>. …”
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16598
Supplementary Table 3 from The Prognostic Significance of Vasohibin-1 Expression in Patients with Upper Urinary Tract Urothelial Carcinoma
Published 2023“…<p>PDF file - 31K, Univariate and multivariate analysis for recurrence-free survival and cancer-specific survival in 171 UTUC patients: We used the cutoff value of MVD � 80/mm2 and VASH1 density � 50/mm2 according to the mean values. The levels of VASH1 density were independent predictors for a decrease in recurrence-free (HR = 2.08) and cancer-specific survival (HR = 2.06)</p>…”
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16599
Phages and <i>Campylobacter</i> isolated on farm 1 and distribution of gamma glutamyl transferase activity.
Published 2014“…<p>A significant decrease of log<sub>10</sub> 1.8 cfu/g in mean <i>Campylobacter</i> counts took place in the investigated flock 2 from day 35 to day 38 (p = 0.00078).…”
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16600
P3490 specifically detects pS137-PFN1 via immunofluorescence staining.
Published 2013“…<i>D</i>, HEK293 cells were transiently transfected with Myc-tagged PFN1(wt, S137A or S137D), treated with 50 µM hydroxyfasudil for 16 hr, and double stained with an anti-Myc (red) and P3490 (green) antibodies. …”