Overexpression of miR-105 inhibits tumour cell growth but does not induce apoptosis. by D. Rice Honeywell (442714)

“…<p>(A–B) Tumour cells were transfected with either 50 nM miR-105 (closed squares) or control (open circles) mimics and subsequently seeded into 96-well plates in replicates of 8. …”

The Effect of Ligand Lipophilicity on the Nanoparticle Encapsulation of Pt(IV) Prodrugs by Timothy C. Johnstone (1312911)

“…As the platinum concentration was increased, there was an initial increase in encapsulation followed by a decrease due to macroscopic precipitation. Maximal loading occurred when the platinum complex was present at a 40% w/w ratio with respect to polymer during the nanoprecipitation step. …”

Figure S1 - SUMOylation Regulates the Transcriptional Repression Activity of FOG-2 and Its Association with GATA-4 by José Perdomo (114665)

Image_2_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF by Dov Borovsky (8892182)

“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”

Image_1_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF by Dov Borovsky (8892182)

“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”

Image_3_Culex quinquefasciatus Late Trypsin Biosynthesis Is Translationally Regulated by Trypsin Modulating Oostatic Factor.TIF by Dov Borovsky (8892182)

“…However, Northern blot analysis showed that TMOF injections did not cause a decrease in trypsin transcript abundance, indicating that TMOF probably affected trypsin translation.…”

PTEN was the downstream target of miR-21 in inducing angiogenesis. by Ling-Zhi Liu (20849)

Characterization of phenotypically unique accessions. by Maria Stefania Przybylska (22756354)

“…</i></i> common accessions classification. Mean Decrease Accuracy (top) and Mean Decrease Gini (bottom) of the random forest models are presented. …”

Cross-talk between LKB1 and Notch signaling. by Pierre-Alexandre Just (187882)

“…<p><b>(A</b>) The RBP-J luciferase reporter was transfected into Mz-Cha-1 cells either alone (0) or with increasing dose of NICD vector (ng) as indicated. …”

Srp drives an overgrowth of the wing disc. by Kyra Campbell (582914)

“…Expression of <i>sna</i> results in a small, but significant decrease in wing disc size (B, D), whereas <i>srp</i> drives a large increase in the size of the GFP expressing compartment (C, D). …”

Overexpression of ST6GAL1 gene enhances the chemoresistance of K562 cells both in vitro and in vivo. by Hongye Ma (424073)

“…IC₅₀ represents the drug concentration producing 50% decrease of cell growth. …”

Immunoblotting of SHP in cisplatin-induced renal injury. by Eun Hui Bae (413566)

“…<p>SHP protein expression was reduced in cisplatin-induced renal injury mice, and it was attenuated by FXR ligand treatment (A). In HK-2 cells, SHP protein exhibited significantly decreased expression after cisplatin (50 µM, 16 h) treatment, and FXR ligand (20 µM, 1 h) pretreatment prevented this cisplatin-mediated decrease in SHP expression (B). …”

Cx43 distribution in CA3 after epileptiform activity. by Erika R. Kinjo (642091)

“…(B, C) Quantification of mean pixel intensity (n = 4 animals per group) showed significant increase in SP and decrease in SR in the acute period (E) compared to controls (D). …”

Telomerase mutant zebrafish have shorter telomeres than WT siblings. by Catarina M. Henriques (102294)

“…D) TRF mean sizes were calculated as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003214#pgen.1003214-Kimura1" target="_blank">[50]</a>. …”

ST266 attenuates RGC loss in mice with mild-moderate EAE optic neuritis. by Keirnan Willett (9946075)

“…(a) The average normalized RGC count across the entire retina shows a decrease in RGC numbers in vehicle-treated EAE mouse eyes (n = 22 eyes) compared to eyes from non-EAE control mice (n = 44 eyes) (*p<0.05). …”

Depletion of TGF-β alters morbidity in HK/486-infected mice. by Christina M. Carlson (240307)

“…<p>Six hours before infection, BALB/c mice were treated with a TGF-β neutralizing antibody (1D11) or an isotype control antibody (IgG) at a dose of 0.5 mg/mouse and subsequently inoculated with PBS (control) or 10⁵ TCID₅₀ units of HK/486 virus (n = 15). …”

Hippocampal cell proliferation and neurogenesis in the dentate gyus. by Suk-Yu Yau (205104)

“…However, BDNF level was decreased by CORT in a dose-dependent manner. Running up-regulated BDNF level in 30 mg/kg and 40 mg/kg CORT-treated rats, but not in 50 mg/kg CORT-treated rats. …”

Global mRNA Expression Profiles of <i>set1</i>Δ and <i>H3-K4R</i> Mutant Strains. by Benoit Guillemette (5650312)

“…A sliding window average was applied to the data on both axes (window  =  50, step  =  1). …”

9.2.27PE in combination with ABT-737 induces apoptosis in melanoma cells. by Karianne Risberg (207221)

“…(D) Cell viability was measured in FEMX cells treated with 9.2.27PE (100 ng/ml)±ABT-737 (10 µM) for 24 h. To determine whether caspases and cathepsins were involved in the decreased cell viability caused by the combination of 9.2.27PE and ABT-737, the cells were pre-treated with for 1 h with Z-VAD-FMK (50 µM)±Z-FA-FMK (50 µM). …”

Summary of collateral dependent blood flow measurements made using manual and automated inflation protocols for before and after transient repetitive myocardia ischemia (RI). by Silas J. Leavesley (555725)