Studies of changes in concentration under different perturbation scenarios. by Xu Gu (276054)

Connectivity properties of the SOM-VIP motif support the amplification in the interneuron network. by Loreen Hertäg (2802439)

“…Smaller mutual inhibition strengths are sufficient to achieve an amplification index above the amplification threshold <i>A</i> = 0 (right). Inset: The dynamics of the mutual inhibition strength (’weight’) after a step increase of the presynaptic firing rate from 0/s to 5/s for three different values of the initial release probabilities. …”

NAP1-Assisted Nucleosome Assembly on DNA Measured in Real Time by Single-Molecule Magnetic Tweezers by Rifka Vlijm (133750)

“…We observe a decrease in end-to-end length when NAP1 and core histones (CH) are added to the dsDNA. …”

Data Sheet 2_Redox regulation of glutamate-1-semialdehyde aminotransferase modulates the synthesis of 5-aminolevulinic acid in Arabidopsis.pdf by Neha Sinha (16927584)

“…Based on these experiments, we propose a redox-dependent structural modification of GSAAT that could lead to a decrease in the activity of the oxidized protein compared to the reduced enzyme.…”

The mitochondrial H⁺ gradient of hypothermic brain mitochondria is reduced relative to physiological temperature. by Matthew E. Pamenter (111599)

“…<b>(B)</b> Percent decrease of mitochondrial respiration, and <b>(C)</b> mitochondrial membrane potential with step-wise addition of malonate. …”

Effect of retinal detachment on electrophysiological properties of Müller cells. by Abdoulaye Sene (258556)

“…B: Inward current amplitudes recorded at a −60 mV hyperpolarizing step. A weakly significant decrease was observed in cells from wt mice. …”

Voltage gating is intrinsic to Cx46 hemichannels by Vytas K. Verselis (53583)

“…When the extracellular solution was essentially devoid of external divalent cations, V gating at +90 mV was unaffected and loop gating at −70 mV was abolished, but application of a very large hyperpolarizing step to −160 mV caused a robust and rapid decrease in current. …”

Data Sheet 1_Redox regulation of glutamate-1-semialdehyde aminotransferase modulates the synthesis of 5-aminolevulinic acid in Arabidopsis.pdf by Neha Sinha (16927584)

“…Based on these experiments, we propose a redox-dependent structural modification of GSAAT that could lead to a decrease in the activity of the oxidized protein compared to the reduced enzyme.…”

Schematic representation of the possible effects of PARP-1 activation on mTORC1 and mTORC2 components and cell death. by Chantal Éthier (36413)

“…PAR transiently accumulates and its metabolism results in a decrease in ATP and NAD⁺ levels, while cellular AMP increases concomitantly. …”

Comprehensive transcriptome analysis and flavonoid profiling of Ginkgo leaves reveals flavonoid content alterations in day–night cycles by Jun Ni (68173)

“…A detailed analysis of individual flavonoids showed that most of their contents were decreased by various degrees. …”

Example of the rules involved in Collagen 1 turnover. by Matthieu Bouguéon (19251466)

“…<p><b>A</b>), Decrease of collagen degradation, the value of <i>token COL</i>1_<i>remodeling</i>_<i>high</i> is decreased and that of <i>COL</i>1_<i>remodeling</i>_<i>low</i> is increased; <b>B</b>), Production of collagen by activated HSCs, the rate of application of the rule is proportional to the value of <i>counter intermediate</i>_<i>step</i>. …”

Hysteresis in vestibular compensation simulation in forward architecture. by John Porrill (35799)

“…<p>In response to a decrease in plant gain (top plot), learning proceeds initially via LTP in the direct pathway (A) and increases VOR gain in the dark by 50% (B); the learning rate has been adjusted to give this stage a time constant of 15 min. …”

Mycolactone induces IL-1β secretion by activating the NLRP3/1 inflammasome pathway. by M. Foulon (9873663)

“…<p>Three known inhibitors of the inflammasome pathway implicated in the secretion of IL-1β were added to LPS-stimulated BMDM cultures in the presence of mycolactone (3 ng/mL) or CPPD (20 μg/mL). <b>A.</b> The addition of 2.5 mM or 25 mM N-acetyl-L-cysteine (NAC) decreased and totally abolished IL-1β secretion, respectively, in the presence of either mycolactone or CPPD. …”

Data_Sheet_1_Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States.pdf by Ning Cao (158319)

Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci by Dennis J. Hazelett (517336)

“…Identification of such enhancer variants and their potential target genes represents a preliminary step in connecting risk to disease process.…”

SPARC-mediated SLUG expression and promotion of melanoma cell migration is PI3K/AKT dependent. by Nina Fenouille (149658)

“…(<b>C</b>) <i>Expression of Myr-AKT protects from SLUG decrease after SPARC depletion:</i> 501mel cells were infected with a control empty adenovirus (AdCMV) or with adenovirus encoding the constitutively active mutant Myr-HA-AKT1 (AdAKT^ca) and transfected 6 hours later with 50 nM siCTRL or siSPARC for 3 days. …”

<i>mir-80</i>(Δ) exhibits multiple characteristics typical of DR animals. by Mehul Vora (94793)

“…Early in adult life, <i>mir-80</i>(Δ) produce a reduced number of live births per day (33% decrease, p<0.05 for Day 3; 180% increase, p<0.001 Day 4–6) and exhibit a prolonged reproductive lifespan (through Day 8 for <i>mir-80</i>(Δ) as compared to WT Day 6, p<0.001). …”

Quantitative phase imaging experimental setup and principle. by Jodie Llinares (8911040)

Related to Fig 4. <i>NDUFS7</i> depletion in neurons lowers the failure rate of neurotransmission at very low calcium concentrations. by Bhagaban Mallik (12459375)

“…The number of failures was counted per hundred trials in each genotype. There is a marked decrease in failure rate in motor neurons driving <i>UAS-NDUFS7[RNAi]</i>. …”

Met-depleted mosquitoes exhibit metabolic defects. by Yuan Hou (767606)