Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

The inhibitory activity of the most active compounds against Glo-I enzyme with less than 50 µM. Their supportive corresponding docking values on two different protocols are display... by MohammedBashar Al-Qazzan (22439236)

SDF1-mediated CXCR4-internalization in NG108-15 cells. by Katrin Feldbauer (3234774)

“…</b> Co-expression of CatCh::mKateA (red) and CXCR4::eYFP (cyan) in presence of 50 nM SDF1α. …”

BT9 exhibits a dose- and time-dependent cytotoxic effect on medulloblastoma. by Zahra Motahari (6814013)

Effects of metformin and/or sodium salicylate on TNFα-induced inflammation in mHypoE-46 neurons. by Wenqing Ye (3015147)

The total muscle and motor unit capacities for initial target forces of 15, 50 and 85% until total muscle capacity decreased to 15% MVC (ie. 85% muscle fatigue for each trial). by Jim R. Potvin (4062412)

SAA in a 50 year-old woman with HHT and severe liver involvement. by Jacques Sellier (8351355)

Dynamic of prolactin in pregnant women during pregnancy. by Francois Kiemde (5369657)

“…Code: *: <0.05; **: <0.01; ***: <0.001; ****: <0.0001. 30μl of plasma was used to determine the concentration of prolactin in blood (ng/ml). Prolactin levels were compared between multigravidae and primigravidae at each scheduled visits as described in “Method” section and presented as box and whisker plots illustration: top, bottom and middle of box, representing 25^th, 75^th and 50^th percentiles, respectively. …”

Visualization and quantification of adhered and internalized <i>C</i>. <i>difficile</i> spores in the ileum and colonic mucosa during aging. by Pablo Castro-Córdova (5614352)

Step and trend changes in the percentage of people reporting a health problem during and after the COVID-19 lockdown, compared to the pre-lockdown period (n = 259,501). by Rodrigo Vargas-Fernández (10164344)

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Growth Kinetics of Elementary Spiral Steps on Ice Prism Faces Grown in Vapor and Their Temperature Dependence by Genki Miyamoto (13914416)

“…We grew prism faces of ice crystals heteroepitaxially on a {101̅0} CdSe wafer. Then, we observed the lateral growth of elementary spiral steps on prism faces in vapor by advanced optical microscopy. …”

Awareness of disabilities in pharmacy program recruitment material: are we doing enough? by Hussain, Farhat Naz

“…Introduction: Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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Depletion of NUP proteins decreases MLV infection of DCs but not NIH3T3 cells. by Karen Salas-Briceno (10934215)

Exclusion in a 9-state-1-step CaM-CaMKII model. by Matthew C. Pharris (4574284)

“…<p>For all traces, models are stimulated by a 2sec pulse of Ca²⁺. (A-C) Active CaMKII subunits over time in our 9-state-1-step model. …”

IL-17A promotes OCP autophagy through the ERK/mTOR/Beclin1 pathway induced by RANKL. by Hao Tang (44155)