Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_1_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_5_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_2_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_3_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Schematic illustration of SER and SER results. by Patrik Wikman (8825663)

Adhesion of Als5 to collagen type IV involves recognition of carbohydrate residues on collagen type IV but is not solely determined by it. by Mohammad Faiz Ahmad (172608)

“…Flow chart representing the various steps of the assay is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0035305#pone.0035305.s005" target="_blank">Figure S5</a>.…”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

Genetic evaluation of growth in Polled Nellore via multi-trait models by Isabella Coutinho de Barros (5939096)

“…Unlikely, a decrease was observed from W205 to W365 for the maternal permanent environmental effect. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

Constraint on the eclogite age of the Sanbagawa metamorphic rocks in central Shikoku, Japan by Shogo Aoki (6440666)

“…It is likely that the older unit was subducted into a depth of over 50 km and stagnated until the younger unit was subducted to the same depth. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new inhibitors. …”

Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

Global Projections of 21^st Century Land-Use Changes in Regions Adjacent to Protected Areas by Linda J. Beaumont (140436)

“…For five periods across the 21^st century, we assessed changes to the extent of primary land, secondary land, pasture and crop land projected to occur within 50 km buffers surrounding IUCN-designated PAs. …”

Data_Sheet_1_Chicken Manure and Mushroom Residues Affect Soil Bacterial Community Structure but Not the Bacterial Resistome When Applied at the Same Rate of Nitrogen for 3 Years.do... by Shuang Peng (1409656)

“…A total of 262 ARG subtypes were detected in chicken manure using high-throughput qPCR, and heat treatment can effectively remove 50 types of ARGs. …”