Impact of KCNE1 expression on WT Kv7.1 and mutant R228C. by Liora Shamgar (44235)

“…Currents were evoked by a train of step depolarization to +30 mV. Similar results have been obtained in 5 other cells.…”

Proteins and mRNAs identified and affected by DA agonists in the hypothalamus of goldfish. by Jason T. Popesku (243373)

“…Negative values indicate a decrease relative to control. Absent values indicate either that no significant change was detected, or, in the case of the mRNAs, that the corresponding cDNA was not present on the array. mRNAs were annotated using Blast2GO's Blast Descriptor Annotator with default values except the Blast ExpectValue was changed from 1.0E-3 to 1.0E-5. …”

What is new in non-chromatographic flavonoid purification? by Leonardo de Oliveira Aguiar (14028342)

“…As the main advantage, these proceedings permitted good yields of bioactive flavonoids and biflavonoids, and they are improved when ultrasound, microwave, and mechanical extractors are used in the extraction step. Nevertheless, most of these techniques are not specific to a single molecule’s purification, except MIPs mainly used for analytical purposes. …”

Lovastatin inhibits VEGF induced activation of AKT and its downstream targets. by Tong T. Zhao (361937)

“…Phosphorylation level of AKT decreased with lovastatin treatment in a dose dependent manner. …”

Loss of intestinal epithelial Shh signaling deregulates intestinal crypt epithelial proliferation. by Jessica Gagné-Sansfaçon (571087)

“…Proliferation assays were performed by PCNA immunostaining (G and H, green labeling), with Evans blue serving as counterstain (red staining). Mutants displayed a decrease in cell proliferation as shown by a decrease in the number of PCNA-labeled proliferating cells (H) when compared to controls (G). …”

Displacement of site marker ligands bound to HSA in presence of increasing PS concentrations. by Shevin R. Feroz (468333)

“…Spectra marked as ‘a’, ‘b’, ‘c’ and ‘d’ refer to 10 µM BR, 10 µM HSA, 50 µM PS and PS–HSA (5∶1) complex, respectively. …”

Examples of CiVSP::cpEGFP constructs expression in HEK293 cells and voltage sensitivity. by Lauren Barnett (136642)

“…The probe exhibits a rapid decrease in fluorescence with a relatively low signal to noise ratio due to relatively weak basal fluorescence. …”

DataSheet_1_Hyperinsulinemia impairs the metabolic switch to ketone body utilization in proximal renal tubular epithelial cells under energy crisis via the inhibition of the SIRT3/... by Jinlan Xie (12917417)

“…The addition of 2 mmol/l BHB improved ATP production, mitochondrial biosynthesis, and endocytic albumin function, while cell apoptosis was reduced in HK2 cells. The addition of 50 ng/ml insulin resulted in the decreased expression of SMCT1 along with an impaired mitochondrial function, decreased ATP production, and increased apoptosis. …”

Shh signaling is required for proper production of goblet cell secretory products and Paneth cell maturation. by Jessica Gagné-Sansfaçon (571087)

“…Immunostaining with an anti-lysozyme antibody showed a decrease in positively-labeled lysozyme cells (green staining) in mutant mice (E) compared to control littermates (D). …”

Aucubin slows the development of osteoporosis by inhibiting osteoclast differentiation via the nuclear factor erythroid 2-related factor 2-mediated antioxidation pathway by Yongfeng Zhang (5963987)

“…<p>Osteoporosis (OP) is a metabolic disease. We have previously demonstrated that aucubin (AU) has anti-OP effects that are due to its promotion of the formation of osteoblasts.…”

Differences in mean scores of upper extremity performance in all five accelerometer-derived variables across four time points- pre-HABIT, post-HABIT, 3-month, and 6-month post-HABI... by Shailesh S. Gardas (20490020)

table_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

table_2_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

Remodeling of Purkinje dendrites in the third postnatal week. by Megumi Kaneko (219519)

“…<b>D</b>: Overpassing branches per cell peak at P18, sharply decrease by P22 and plateau thereafter. <b>E</b>: The mean length of each dendritic branch decreases between P7 and P9, constantly increases until P35 and then slightly decreased by P50. …”

image_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.EPS by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

Expression of calpastatin in rhodopsin transgenic rats. by Jasvir Kaur (123596)

“…<p>(<b>A</b>) Immunoblotting for calpastatin showed decreased levels in both, P23H and S334ter rats. …”

ToxCast™Phase I chemical activity across cytotoxicity and differentiation ES cell assay endpoints. by Kelly J. Chandler (218453)

“…Unsupervised, two-dimensional hierarchical clustering of 320 ToxCast chemicals across four ES cell assay endpoints (cytotoxicity increase, cytotoxicity decrease, differentiation increase, differentiation decrease) and 4 doses each using Euclidean distance for measure and Ward's method for linkage analysis (A). …”

The exocyst is required for cell cycle progression in trypanosomes. by Cordula M. Boehm (3689848)

“…Sec15::RNAi cells have a ∼50% decrease to Sec15::HA 48h post induction, whilst expression of Exo99 remains stable, and <i>vice versa</i>. …”

Data Sheet 2_RvD2 mitigates TNFɑ-Induced mitochondrial reactive oxygen species through NRF2 signaling in placental trophoblasts.pdf by Taija Hahka (20983223)

“…</p>Methods<p>We investigated RvD2’s potential protective mechanisms against TNFα‐induced oxidative stress in trophoblasts by pretreating JEG cells with 100 nM RvD2, followed by exposure to 50 or 100 ng/mL TNFα.…”

Data Sheet 1_RvD2 mitigates TNFɑ-Induced mitochondrial reactive oxygen species through NRF2 signaling in placental trophoblasts.pdf by Taija Hahka (20983223)

“…</p>Methods<p>We investigated RvD2’s potential protective mechanisms against TNFα‐induced oxidative stress in trophoblasts by pretreating JEG cells with 100 nM RvD2, followed by exposure to 50 or 100 ng/mL TNFα.…”