Proteins from the TSC/mTOR pathway are regulated by p19. by Maria Camats (255397)

“…C) western blot analysis with anti-p-70S6K (Thr389) antibodies on proteins from HeLa cells transfected with pRK5, pRK5-p19, and pRK5-p19mut. A decrease of p-70S6K by 50% were quantified in lanes pRK5-p19 versus pRK5. …”

Complex Formation between NheB and NheC Is Necessary to Induce Cytotoxic Activity by the Three-Component <i>Bacillus cereus</i> Nhe Enterotoxin by Uta Heilkenbrinker (408526)

“…Toxicity, however, showed a bell-shaped dose-response curve with a plateau at ratios of NheB and NheC between 50:1 and 5:1. …”

Influence of Ca²⁺-chelation on the individual binding interfaces of N-cadherin. by Stefanie Bunse (491659)

“…This confirms the hypothesis that the X-dimer is a Ca²⁺-dependent intermediate step in the formation of the strand-swapped dimer. n(WT) = 8, n(W2A) = 8, n(R14E) = 9, n(V81D/V174D) = 7 junctions. …”

PSimScan: Algorithm and Utility for Fast Protein Similarity Search by Anna Kaznadzey (386409)

“…The first step in this pipeline is a novel algorithm that builds and selects ‘similarity zones’ aggregated from neighboring matches on small arrays of adjacent diagonals. …”

Y-27632 treatment of P19 cells inhibits the differentiation of primitive endoderm. by Roman J. Krawetz (309735)

“…FACS analysis demonstrates a significant decrease in GATA-6 and Troma-1 positive cells with Y-27632 present (K). …”

Menthol and eugenol as natural anesthetics for early juveniles of curimba by Elias Fernandes de Medeiros Junior (4832202)

“…Increased concentrations led to a decrease in recuperation time. The concentrations between 50 to 70 mg of eugenol L−1 provided the lowest induction times; however, recovery time was not affected by eugenol concentrations. …”

Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

Temporal analysis of behavioral transitions across five time intervals in the visual cliff setup. by Hironobu Shuto (22127141)

“…Circular paths show consistent cliff effects during the 0–3 min interval, with clear transitions in state fractions between points “a” and “b”. However, the cliff effect diminishes during the 6–9 min interval and reappears in the 12–15 min interval, though its interpretation is complicated by changing state definitions (e.g., progressively smaller step lengths). …”

Effects of endogenous prostanoids and selective agonists on the beating rate of neonatal rat cardiomyocytes. by Hakima Mechiche (308181)

“…“bradyarrhythmia” indicated a decrease of more than 50%; “tachyarrhythmia” indicated an increase of more than 50% with chaotic, asynchronous, activity of the myocytes <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045273#pone.0045273-Li1" target="_blank">[13]</a>; <i>n</i> is the number of preparations on which brady- or tachy-arrhythmia was observed.…”

pQTL analysis of IFN-α and IFN-γ receptor levels and responses. by Christian Lundtoft (4068679)

“…Blue indicates a decrease in minor allele carriers, while red indicates an increase in minor allele carriers. …”

Only 52 of the 256 possible genotypes between PfCRT^3D7 and the CQ-transporting PfCRT^Dd2 isoform have measured phenotypes. by Zachary R. Sailer (4025459)

“…This trajectory passes through the PfCRT^{China e} and PfCRT^K1 isoforms. Five of the eight steps increase CQ transport activity, two have no effect, and the final step causes a decrease.…”

Table_6_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_10_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_12_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_9_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_7_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_8_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_15_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Image_1_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.TIF by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”

Table_11_Biological, Behavioral and Physiological Consequences of Drug-Induced Pregnancy Termination at First-Trimester Human Equivalent in an Animal Model.DOCX by Christina Camilleri (6751091)

“…Following drug/vehicle administration, only the pregnancy termination group (pregnant, drug) displayed a significant decrease in body weight, food intake, locomotor activity-related behaviors and home-cage activity relative to the control group (non-pregnant, vehicle). …”