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7481
VEGF and sFlt-1 mutants exhibit changes in stem cell marker gene expression by RT-qPCR.
Published 2016“…(B) Bmi1 expression decreased 0.42 fold (*p = 0.03) and Wdr43 expression decreased 0.60 fold (*p = 0.004) in sFlt-1 mutants compared to littermates. sFlt-1 mutants demonstrated a 2.47-fold increase in expression of EphB2 (*p = 0.02) and a 1.50-fold increase in Sox9 expression (*p = 0.004); N = 6 mice per group; Error bars = STDEV.…”
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7482
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7483
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7484
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7485
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7486
TRACMIT: An effective pipeline for tracking and analyzing cells on micropatterns through mitosis
Published 2017“…Despite being powerful, such screens remain challenging in terms of data handling and analysis. Typically, only a fraction of micropatterns is occupied in a manner suitable to monitor a given phenotypic output. …”
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7487
Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events
Published 2021“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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7488
PPM1A is critical for proliferation of intestinal organoids.
Published 2021“…A dramatic lower number of de novo crypts (D, top panel) and the decreased size of organoids (D, bottom panel) were seen in organoids from PPM1A KO mice, with roughly 50 intestine organoids each group examined. …”
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7489
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity
Published 2018“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC<sub>50</sub> 0.16–0.82 μM. …”
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7490
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity
Published 2018“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC<sub>50</sub> 0.16–0.82 μM. …”
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7491
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity
Published 2018“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC<sub>50</sub> 0.16–0.82 μM. …”
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7492
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity
Published 2018“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC<sub>50</sub> 0.16–0.82 μM. …”
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7493
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity
Published 2018“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC<sub>50</sub> 0.16–0.82 μM. …”
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7494
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity
Published 2018“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC<sub>50</sub> 0.16–0.82 μM. …”
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7495
Image_1_IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.TIF
Published 2018“…</p><p>Results: Our main findings were (i) Tocilizumab decreased C5aR1 and C5aR2 mRNA expression significantly (p < 0.001) and substantially (>50%) at day 2 and 3, whereas C3aR expression was unaffected. …”
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7496
Image_2_IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.TIF
Published 2018“…</p><p>Results: Our main findings were (i) Tocilizumab decreased C5aR1 and C5aR2 mRNA expression significantly (p < 0.001) and substantially (>50%) at day 2 and 3, whereas C3aR expression was unaffected. …”
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7497
Table_1_IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.DOCX
Published 2018“…</p><p>Results: Our main findings were (i) Tocilizumab decreased C5aR1 and C5aR2 mRNA expression significantly (p < 0.001) and substantially (>50%) at day 2 and 3, whereas C3aR expression was unaffected. …”
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7498
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7499
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7500
Aging effects on airflow dynamics and lung function in human bronchioles
Published 2017“…</p><p>Findings</p><p>The airway mechanical characteristics decreased with aging, specifically a 38% pressure drop was observed for the 80-year-old as compared to the 50-year-old. …”