DCP-LA treatment of SN56 cells diverts APP into early endosome compartments. by Joshua H. K. Tam (836784)

Mutational landscape of TCL cell lines. by Rufino Mondejar (4025846)

Effectiveness of community-based complementary food supplement (Yingyangbao) distribution in children aged 6-23 months in poor areas in China by Jie Wang (16762)

“…Compared with the baseline situation (n = 823), the proportion of children fed a diverse diet and foods rich in iron or vitamin A increased (<i>P</i> < 0.01) in the follow-up study. …”

Difficulty as a function of the level. by Federico Zimmerman (3607586)

Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells by Magdalena Circu (4458754)

“…We investigated whether triggering lysosomal membrane permeabilization (LMP) or suppressing autophagy can restore cisplatin susceptibility in lung cancer with acquired chemoresistance. Cisplatin IC₅₀ in A549Pt (parental) and A549cisR (cisplatin resistant) cells was 13 μM and 47 μM, respectively. …”

Poly (A) Binding Protein Cytoplasmic 1 Is a Novel Co-Regulator of the Androgen Receptor by Kurtis Eisermann (95302)

“…Co-immunoprecipitation assays confirmed the association of PABPC1 with a.a. 50-250 of the NTD of the AR. Knockdown of PABPC1 decreased nuclear AR protein levels and inhibited androgen activation of the AR target PSA in LNCaP and C4-2 cells. …”

DCB-3503, a Tylophorine Analog, Inhibits Protein Synthesis through a Novel Mechanism by Ying Wang (11406)

“…DCB-3503 inhibited the incorporation of radiolabeled amino acid and thymidine, and to a much lesser degree of uridine, in a panel of cell lines. …”

Video_1_Biomechanics of In-Stance Balancing Responses Following Outward-Directed Perturbation to the Pelvis During Very Slow Treadmill Walking Show Complex and Well-Orchestrated Re... by Zlatko Matjačić (5090498)

“…In the second part of the response the lateral ground-reaction-force was decreased with respect to unperturbed walking thus allowing for a decrease of whole-body angular momentum in the frontal plane. …”

GO annotation analyses of DEGs. by Benzun Wei (21485639)

Soluble lytic transglycosylase SLT of <i>Francisella novicida</i> is involved in intracellular growth and immune suppression by Takemasa Nakamura (8190540)

Tyrosine motif mutations affect on APP/AP-3 interaction. by Joshua H. K. Tam (836784)

⁶⁸Ga-Labeled TMTP1 Derivatives with Moderate Hydrophilicity for Positron Emission Tomography of Hepatocellular Carcinoma in High Contrast by Xiaowei Fan (10198883)

“…Subnanomolar and nanomolar affinities comparable to the non-PEGylated TMTP1 derivative were revealed by the IC₅₀ values in SMMC-7721 cells. [⁶⁸Ga]Ga-NOTA-PEG₂-TMTP1 presented a significantly higher tumor/liver ratio (4.19 ± 0.54, at 30 min post intravenous injection) and tumor/muscle ratio (2.14 ± 0.17) compared to the others and the previously radiolabeled TMTP1 derivatives. …”

Effect of fenretinide and its metabolites on SCD expression and activity. by Eugenia Poliakov (116500)

“…<p>A) SCD1 protein expression is decreased after treatment with fenretinide, and its metabolite 3-keto-HPR. …”

Contour plot of thresholds to achieve national and ambitious targets with varying levels of management cost reductions and treatment cost reductions. by Andrew J. Shattock (720510)

“…The ‘no increase’ contour is the threshold for satisfying the national targets (and is hence the border for the light grey region), whilst the ‘50% decrease’ contour satisfies the ambitious targets (and is hence the border for the dark grey region). …”

Neonatal Intensive Care in a Karen Refugee Camp: A 4 Year Descriptive Study by Claudia Turner (160713)

“…Early prematurity (<34 weeks) carried the highest risk of mortality (OR 9.5, 95% CI 5.4–16.5, p<0.001). There was a significant decrease in mortality from 19.3% (2008) to 4.8% (2011) among the infants admitted for prematurity (p=0.03). …”

All naive T cells undergo turnover throughout adult life. by Jeff E. Mold (7571855)

Performance comparison of three loss functions. by Yaojun Zhang (389482)

Image_8_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

Image_6_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)

Image_7_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG by Wen-I Liao (586146)