Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Missense mutations of the HNF1A were retrieved from public databases and subjected to a three-step computational mutational analysis to identify the underlying mechanism. …”
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Rape-related symptoms in adolescents: short- and long-term outcome after cognitive behavior group therapy by Iva Bicanic (14339079)

“…</p> <p>The aim of this prospective observational study was to evaluate the short- and long-term outcomes of a nine-session cognitive behavior group therapy (STEPS), including a parallel six-session parents’ group on rape-related symptomatology in female adolescents (13–18 years). …”

Dimethyl Sulfoxide Perturbs Cell Cycle Progression and Spindle Organization in Porcine Meiotic Oocytes by Xuan Li (137217)

Pairwise comparisons of the main effect of the Condition (a) and the main effect of the Group (b), for the parameter relative power. by Yogev Koren (11610314)

Simulating within-vector generation of the malaria parasite diversity by Lauren M. Childs (593877)

“…However, diversity increases with the possibility for recombination and proliferation in the formation of sporozoites. Furthermore, when we begin with two parasite subpopulations in the initial gametocyte population, the probability of transmitting more than two unique parasites from mosquito to human is over 50% for a wide range of initial gametocyte densities.…”

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

Dose response association of objective physical activity with mental health in a representative national sample of adults: A cross-sectional study by Paquito Bernard (5892197)

“…For daily steps, inverted U-shaped curve suggested increasing benefits until a plateau between 5 000 and 16 000 steps. …”

Localization of key HH signaling proteins is impaired in <i>Ttbk2</i>^{<i>sca11/gt</i>} cilia. by Emily Bowie (543704)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

“…JQ1 (50–400 nM) increases insulin secretion from INS-1 cells in a concentration dependent manner. …”

Competitive binding experiment. by Deepu Dowarha (5673440)

Src-induced tyrosine phosphorylation of Kv2.1 in CHO cells is significantly decreased in Kv2.1(S800A) mutants. by Kai He (157282)

Transmission electron micrographs of step 5 spermatids. by Yonggang Lu (358237)

“…<p><b>(A)</b> As the nuclear size (N) of step 5 spermatids decreases, the decondensed chromosomes are aggregated into a retiform pattern. …”

Time step selection for pressure field calculation. by Kelsey N. Lucas (4669798)

“…(A) The noise in the force trace from pressure-based force calculations decreased as time step (dT) increased. …”

Sample size estimation for stepped wedge design. by Eric Nturibi (10163914)

“…<div><p>While the incidence of Human Immunodeficiency Virus (HIV) infection is decreasing in most age groups worldwide, it is rising among adolescents and young adults, who also face a higher rate of HIV-related deaths. …”

DNase I overexpression reduced <i>A3A</i> upregulation upon MeV infection. by Pierre Khalfi (7868252)

Summary plot for the effect of important food sources of fructose-containing sugars on diastolic blood pressure (DBP). by Qi Liu (33068)

Intravenous treatment of naïve wild-type mice with PrP LSPCs decreased PrP^C mRNA and cell surface PrP^C protein at various time points. by Heather Bender (363996)

National contributions to urban sprawl (2014), weighted sprawl per capita (2014), and to the respective changes (1990–2014) at the scale of a global 50 × 50 km² grid. by Martin Behnisch (7285397)

<em>C. elegans</em> Mutant Identification with a One-Step Whole-Genome-Sequencing and SNP Mapping Strategy by Maria Doitsidou (237951)

“…We describe here our experience in setting up and testing a simple strategy that incorporates a rapid SNP-based mapping step into the WGS procedure. …”

Quantitative analyses of ROS levels in IPEC-J2 cells incubated for 2 hours (2A, 2B), 24 hours (2C, 2D) and 48 hours (2E, 2F) with inhibitor MI-432 at different concentrations (10,... by E. Pászti-Gere (816855)