Table1_Effect of ribose-glycated BSA on histone demethylation.XLSX by Mengqi Xi (13908819)

“…Riboglycated BSA, which was incubated with ribose for approximately 7 days, showed the strongest cytotoxicity, leading to a significant decrease in the viability of SH-SY5Y cells cultured for 24 h (IC₅₀ = 1.5 μM). …”

All-atom molecular dynamics simulation of peptides by Ning Zhu (10901010)

“…<p>The initial structure was built using the LEaP module of AmberTools21, and we will run a total of 4000 minimization steps before starting to run molecular dynamics; 2000 is the steepest decline, followed by the conjugate gradient of 2000. …”

Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011 by Louisa B Goss (757328)

“…We found a significant decrease in annual hospital mortality over the study period [odds ratio(OR): 0.92 per year, 95% CI 0.88-0.96, P<0.001]. …”

Patterns of lake ice cover are changing throughout the Northern Hemisphere. by Alessandro Filazzola (6631649)

“…Depending on the greenhouse gas emissions, we predict a loss of between 50,000 and 200,000 km² of ice cover. …”

Mithramycin Exerts an Anti-Myeloma Effect and Displays Anti-Angiogenic Effects through Up-Regulation of Anti-Angiogenic Factors by Eléonore Otjacques (410361)

“…In rat aortic ring assays, a strong anti-angiogenic effect was seen, which could be explained by a decrease of VEGF production and an up-regulation of anti-angiogenic proteins such as IP10 after MTM treatment. …”

Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells by Kateřina Kuželová (541883)

“…IPA-3 induced cell death with EC50 ranging from 5 to more than 20 μM. Similar range was found for IPA-3-mediated dephosphorylation of a known PAK downstream effector, cofilin. …”

Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation by Zeynep BAYRAMOGLU (13826448)

“…<div><p>Abstract The role of oxidative stress, as well as inflammation in the pathogenesis of methotrexate (MTX)-induced oral mucositis, is a known fact. The anti-inflammatory, antitumor, antimicrobial, and antioxidant properties of taxifolin—the effect we tested against MTX-induced oral mucosal damage—are well known. …”

Factors associated with the <i>SS</i> Positives. by Anuradha Rajamanickam (5278013)

“…<div><p><i>Strongyloides stercoralis (Ss)</i> is a parasitic infection affecting 50–100 million people globally, with significant immune and metabolic consequences, particularly in immunocompromised individuals. …”

Impact of the 2009 US Preventive Services Task Force Guidelines on Screening Mammography Rates on Women in Their 40s by Amy T. Wang (533749)

“…Time-series regression models were estimated to determine the effect of the guideline change on screening mammography rates. 5.5 million women ages 40–64 were included. A 1.8 per 1,000 women (p = 0.003) decrease in monthly screening mammography rates for 40–49 year-old women was observed two months following the guideline change; no initial effect was seen for 50–64 year-old women. …”

Data_Sheet_1_Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology.docx by Thamires Siqueira Oliveira (11398496)

“…Total and healthy mitochondria were reduced by 30% in septic mice, which may be associated with a 50% decrease in Ppargc1a (encoding PGC1a) and Opa1 (mitochondria fusion marker) expressions in the septic diaphragm. …”

Response kinetics and relationship to Weber’s law in the m8 controller (Fig 10). by Jonas V. Grini (15374504)

“…<p>The set-point of <i>A</i> is <i>A</i>_<i>set</i>=3.0. (a) Step-wise increase of <i>k</i>₁ from 1.0 to 5.0 at time <i>t</i>=100 at different and constant background perturbations <i>k</i>₃ (0–80). …”

The immune control exerted by lytic and non-lytic CD8+ T cell responses. by Nafisa-Katrin Seich al Basatena (201133)

“…Here we show the results for the non-lytic control that blocks viral infection, similar results were found for non-lytic control that blocks viral production (Figures S6, S7 in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003656#ppat.1003656.s001" target="_blank">Text S1</a> and data not shown). …”

Comparative Proteomics Unravels the Differences in Salt Stress Response of Own-Rooted and 110R-Grafted Thompson Seedless Grapevines by Sucheta Patil (8162292)

Table_1_Baseline mitochondrial DNA copy number and heart failure incidence and its role in overall and heart failure mortality in middle-aged women.pdf by Kristina Sundquist (83374)

“…Baseline levels of mtDNA-CN were quantified by droplet digital PCR in a population-based follow-up study of middle-aged (50–59 years) Swedish women (n = 2,508). …”

Image_2_Pulsed Infrared Stimulation of Vertical Semicircular Canals Evokes Cardiovascular Changes in the Rat.eps by Darrian Rice (10888116)

Image_6_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_1_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_5_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”

Image_2_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF by Yang Kong (3376658)

“…GG inhibited viability and proliferation of GBM cells (U251, U87MG, and A172) in a dose-dependent manner (IC₅₀ = 221.8, 262.5, 273.9 μM, respectively; P < 0.001; EdU, ~40% decrease at 150 μM, P < 0.001), and the number of colonies formed was significantly reduced (at 50 μM, P < 0.001). …”