Clinical endpoints in the controlled human challenge model for <i>Shigella</i>: A call for standardization and the development of a disease severity score by Chad K. Porter (2552560)

“…The median maximum 24 hour stool output was 514 ml (IQR: 300, 998 ml) with a median frequency of 6 (IQR: 4, 9). Subjects reported abdominal pain or cramps (81.5%), headache (66.7%) and anorexia (64.8%), 50.0% had a fever and 27.8% had gross blood in multiple loose stools. …”

Test design list. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

GDS triaxial apparatus. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

Shear strength indicators. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

miR-184 expression correlates with different class of septate junctions. by Sravya Paluri (5475260)

Table_1_Abrupt elevation of tumor marker levels in a huge splenic epidermoid cyst, a case report.docx by Hao Cai (1324782)

“…Most published case reports provided inadequate information on the impact of splenic epidermoid cyst on tumor markers. A 32-year-old woman with a giant splenic epidermoid cyst was reported, for whom the serum concentration of a collection of tumor markers (CA19–9, CEA, CA125, CA242, and CA50) increased abruptly accompanied by left upper abdominal pain for 5 days. …”

A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase by Kenneth W. Yip (257594)

“…This species, a porphodimethene (named PI-16), was found to inhibit UROD in an enzymatic assay (IC₅₀ = 9.9 µM), but did not affect porphobilinogen deaminase (at 62.5 µM), thereby exhibiting specificity. …”

DataSheet_1_Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases.docx by Solène Frileux (9043280)

“…Both presented severe sensitivity to antipsychotic agents that led to a diagnosis of Dementia with Lewy Bodies. Administration of cholinesterase inhibitors was associated with decrease of psychiatric symptoms in both cases. …”

Expression of NS4A(1–48) wild type and mutant peptides using a dual GST-GB1 tag. by Yu-Fu Hung (513472)

“…A densitometric analysis of the respective bands revealed a cleavage efficiency of approximately 50% for the wild type peptide.…”

Triaxial test scheme of expansive soil. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

Soil samples during the testing process. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

RNAi controls and <i>pyr-GAL4</i> expression (related to Fig 5). by Yuting Lei (9624598)

RhoA activity in cells exposed to CaR agonists. by Giuseppe Procino (330755)

“…In cells pretreated with 300 µM Gd³⁺, RhoA activity was significantly increased (decreased FRET signal, n = 50) compared to control untreated cells. …”

Switching the Adhesive State of Catecholic Hydrogels using Phototitration by Evan M. White (1879558)

“…Irradiation of these hydrogels with UV light affords a viscous liquid solution, demonstrating a gel–sol transition with a subsequent decrease in the adhesive strength of the material. …”

Systematic errors and base quality score recalibration. by Justin M. Zook (146772)

“…<p>(a) Observed variants in the reads can result from a variety of biological causes and sequencing errors and biases. (1) Random sequencing errors are relatively rare at any given position in the reference, and are generally reflected accurately in the reported base quality score from the instrument. (2) Biological variants that are included in the SNP database (e.g., dbSNP for humans) are excluded from the base quality score recalibration (BQSR), and therefore do not decrease the empirical quality scores. (3) RNA editing can occur at frequencies less than 50%, so it can be difficult to distinguish from SSEs. …”

A. Inhibition of the effect of pyruvate on lactate utilization by phenylpyruvate. by Scott John (228011)

“…Recordings in panel B are representative traces of the decrease in intracellular lactate level induced by the addition of pyruvate in the double HKI-HKII kd cells under control conditions (B1) and after a 48hr incubation with the inhibitor of ME1 (ME1*) at a concentration of 50μM (B2). …”

<i>SU-like sensitive</i> and <i>SU-like VRC26 early escape</i> viruses are differently neutralized post CD4 attachment. by Lucia Reh (546554)

Period of a stable limit cycle in the AFHN model. by Seth H. Weinberg (154341)

Prolonged Glycemic Adaptation Following Transition From a Low- to High-Carbohydrate Diet: A Randomized Controlled Feeding Trial by Lisa T Jansen (11876618)

“…The number of participants with abnormal glucose tolerance by OGTT remained 10 (of 16) in VLC at start and end but decreased from 17 to 9 (of 25) in both HC groups.</p> <p><b>Conclusions: </b>Physiological adaptation from a low- to high-carbohydrate diet may require many weeks, with implications for the accuracy of diabetes tests, interpretation of macronutrient trials, and risks of periodic planned deviations from a VLC diet.…”

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit by Al-Sulaiti, Fatima Khalifa

“…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …”
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