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6861
Controls and experimental setup for calcium flux assays.
Published 2017“…<b>(i)</b> Compounds (orange) are added as a 30 μM– 30 nM CRC (decreasing color saturation). …”
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6862
Data_Sheet_1_The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool.docx
Published 2020“…The stx<sub>2a</sub>+ isolate was avirulent. Both an stx<sub>2a</sub> and a recA deletion mutant of one of the stx<sub>2a</sub>+stx<sub>2c</sub>+ strains, JH2010, exhibited at least a three-log decrease in cytotoxicity in vitro and both were avirulent in the mice. …”
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6863
Kinetic Study of the Effects of Inhibitors on the Catalyzed Dehydration of HCO<sub>3</sub><sup>-</sup> by Copper(II) Complexes [Tp<sup>Ph</sup>]CuX (X<sup>-</sup> = OH<sup>-</sup>,...
Published 2002“…The catalytic activity decreases with increasing pH indicating that the aqua model complex must be the reactive catalytic species in the catalyzed dehydration reaction and the rate-determining step is the substitution of the labile water molecule by HCO<sub>3</sub><sup>-</sup>. …”
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6864
Effect of Oxidative Phosphorylation Inhibitors on <i>In Vivo</i> Tat Transport and Sensitivity of Fluorescence Detection on Plates.
Published 2016“…Valinomycin (V; 50 μM) is a K<sup>+</sup> ionophore, which collapses the Δψ. …”
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6865
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6866
Inhibition correlates with cellular PmV levels.
Published 2015“…Comparisons of IC<sub>20</sub>, IC<sub>50</sub> and IC<sub>80</sub> values are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0142509#pone.0142509.t001" target="_blank">Table 1</a> and derived from curves shown in B. 3D7 and DC6 cultures expressed similar levels of Plasmepsin V; while G6 in the absence of Shield-1 showed decreased, and #3 showed augmented, levels of the cellular enzyme concentration. …”
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6867
The inhibitory ability of curcuminoids on the GSSG reductase activity of <i>Tc</i>TGR.
Published 2019“…<p>(a). A reduced enzyme aliquot was incubated in TE buffer in the presence of either Curcumin (□), DMC (■), or BDMC (●) at the indicated concentration. …”
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6868
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6869
Questionnaire items on smoking.
Published 2024“…In the period 1930–2005, 27.3% of 9,605 people aged 36–50 years who smoked ceased smoking. Rates of cessation in this age group increased throughout but decreased in males after 1990 and plateaued around 2000 in females.…”
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6870
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6871
Immunohistochemical staining showing the expression of phosphorylated p38 in the mouse renal tubulointerstitial area after UUO and administration of p38 MAPK inhibitor.
Published 2019“…<p>Scale bar = 50 μm (original magnification x300). (A) Sham-operated group. …”
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6872
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity
Published 2017“…More than 100 new compounds were synthesized, which target the overwhelming the defects of the CrtN inhibitor <b>1</b>. Analogues <b>23a</b> and <b>23b</b> demonstrated a significant activity against pigmented <i>S. aureus</i> Newman and 13 MRSA strains (IC<sub>50</sub> = 0.02–10.5 nM), along with lower hERG inhibition (IC<sub>50</sub> > 30 μM, ∼10-fold decrease in comparison with <b>1</b>). …”
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6873
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6874
<i>VT16839-Gal4</i> neurons trigger and are critical in consumption behavior.
Published 2017“…<p><b>A)</b><i>VT16839-Gal4</i> drives expression of <i>UAS-mCD8</i>::<i>GFP</i> in the brain and VNC (scale bar = 100 μm) <b>B)</b> RNA interference knockdown of <i>Rdl</i> in <i>VT16839-Gal4</i> neurons increased consumption time of water, 1 mM denatonium, 500 mM sucrose and 20% PEG. …”
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6875
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6876
Ruthenium-Catalyzed Ionic Hydrogenation of Iminium Cations. Scope and Mechanism
Published 2005“…A methyl substituent on the Cp ring decreases the H<sup>-</sup> transfer rate and the turnover frequency slightly. …”
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6877
Ruthenium-Catalyzed Ionic Hydrogenation of Iminium Cations. Scope and Mechanism
Published 2005“…A methyl substituent on the Cp ring decreases the H<sup>-</sup> transfer rate and the turnover frequency slightly. …”
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6878
Desiccated <i>Aedes</i> eggs remodel their proteome towards lipid metabolism and TCA cycle.
Published 2023“…The number of eggs used per trial = 50. Also see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002342#pbio.3002342.s001" target="_blank">S1F Fig</a> which illustrates how <i>Aedes</i> eggs were collected for the preparation of lipid extracts. …”
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6879
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6880
Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat
Published 2023“…Xanthine oxidase (XO) is a member of the molybdopterin-containing enzyme family. …”