Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat by Yazdan Maghsoud (6560168)

“…Xanthine oxidase (XO) is a member of the molybdopterin-containing enzyme family. …”

Molecular Modeling-_Based Delivery System Enhances Everolimus-Induced Apoptosis in Caco‑2 Cells by Marwan Abdelmahmoud Abdelkarim Maki (6725999)

“…However, the meaningful efficacy of EV as a single agent for the treatment of colorectal cancer (CRC) has failed to be proven in multiple clinical trials. …”

Paxilline and NS11021 sensitive mitoBK channels give rise to a 190 pS conductance, which is absent in BK-negative mitoplasts. by Ewa Soltysinska (605651)

“…(<b>B</b>) Four different conductances were observed in mitoplasts from cardiomyocytes in a voltage step protocol with 2 seconds at +80 mV followed by 3 seconds at holding potential (−50 mV). …”

DataSheet_1_Effects of Acipenserid herpesvirus 2 on the outcome of a Streptococcus iniae co-infection in white sturgeon (Acipenser transmontanus).docx by Eva Marie Quijano Cardé (6944261)

“…While a decrease in humoral immunity caused by VZV has been hypothesized as a potentially important factor in IGASI cases, no natural animal model exists to study this process. …”

Five genes involved in piRNA biosynthesis were commonly down-regulated in the two <i>enok</i> mutants as compared with the WT control, while the expression levels of <i>piwi</i>, <... by Shih-Ying Tsai (3576587)

NTF effect on neuronal morphologies Effect of 50 ng/ml BDNF, 100 ng/ml CNTF and the combination of both NTFs (B/C) compared to negative control (NC) on neuronal morphology in terms... by Jana Schwieger (782065)

Concentration-dependent activation and inhibition of hSGLT1 measured by membrane potential-dependent changes in fluorescence. by R. Kyle Palmer (20284957)

Clathrin-dependent endocytosis is associated with RNAi response in the western corn rootworm, <i>Diabrotica virgifera virgifera</i> LeConte by Daniele H. Pinheiro (5617250)

“…Silencing of <i>Chc</i>, <i>Vha16</i>, and <i>AP50</i> led to a significant decrease in the effects of <i>laccase2</i> dsRNA reporter, indicating that these genes are involved in RNAi response. …”

Fig 9 - by Yi-xiao Liu (14769126)

Drebrin regulates RMS neuroblast migration <i>in vitro</i>. by Martina Sonego (481270)

“…The GFP channel is shown as a grayscale image. (B) Drebrin-depleted neuroblasts (black column) show a ~20% decrease in migration distance compared to control shRNA-nucleofected cells (white column). …”

Drebrin phosphorylation on S142 regulates neuroblast morphology and orientation <i>in vivo</i>. by Martina Sonego (481270)

“…(B) Quantitative morphological analysis also shows a decrease in leading process length for wt, S142A and S142D compared to the control (mean ± SEM; n = 8 brains for empty vector; n = 5 brains for wt, S142A, and S142D drebrin; *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001). …”

Receiver operating characteristic (ROC) curves. by Dandan Gong (5744666)

“…The optimal cut-off point of the CD4⁺ count was 50 Nr/μl or less. Among the 350 patients received both fungal culture and Mp1p antigen detection, 95/350 (27.1%) patients were culture-positive for a <i>Talaromyces marneffei</i>, 75/350 (21.4%) patients were Mp1p antigen positive. …”

Cut-point analysis using Youden’s J Index. by Dandan Gong (5744666)

“…The optimal cut-off point of the CD4⁺ count was 50 Nr/μl or less. Among the 350 patients received both fungal culture and Mp1p antigen detection, 95/350 (27.1%) patients were culture-positive for a <i>Talaromyces marneffei</i>, 75/350 (21.4%) patients were Mp1p antigen positive. …”

Fig 1 - by Spencer L. Nystrom (8730641)

LncRNA NORAD engages in psoriasis by binding to miR-26a to regulate keratinocyte proliferation by Shuiqi Li (10426496)

Fig 2 - by Spencer L. Nystrom (8730641)

Additional within-case comparison information. by Ryan J. Treves (13527735)

“…In 1999, California introduced changes to its clean water program that modified each of these components, and in the present work we explore the impact of these changes using a mixed-methods approach. While the state’s introduction of $3,000 mandatory minimum penalties for certain Clean Water Act effluent and reporting violations by permitted wastewater facilities reflected a significant step-up in enforcement, the policy also allowed small communities with financial hardship to redirect penalties toward investments in compliance. …”

POTW sample summary. by Ryan J. Treves (13527735)

“…In 1999, California introduced changes to its clean water program that modified each of these components, and in the present work we explore the impact of these changes using a mixed-methods approach. While the state’s introduction of $3,000 mandatory minimum penalties for certain Clean Water Act effluent and reporting violations by permitted wastewater facilities reflected a significant step-up in enforcement, the policy also allowed small communities with financial hardship to redirect penalties toward investments in compliance. …”

Thermal, Physical, and Electrochemical Properties of Li[N(SO₂F)₂]‑[1-Ethyl-3-methylimidazolium][N(SO₂F)₂] Ionic Liquid Electrolytes for... by Kazuhiko Matsumoto (1611913)

“…Aluminum corrosion at positive potentials was investigated by a potential step method, which revealed that the stability of an aluminum electrode was improved at high Li­[FSA] fractions at 298 K, and the corrosion-limit potential decreased at elevated temperatures.…”

S4 Fig - by James M. Burke (14041162)