An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos by Sergio Jarque (5698859)

“…<div><p>The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent imaging of reporter gene fluorescence in the thyroid gland of embryos of the transgenic zebrafish line tg(tg:mCherry). …”

Electrical impedance cole parameters. by W. David Arnold (3373874)

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”

Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N‑Chelated and Pyridine Ligands by Zhe Liu (77240)

“…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe₂) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt₂) decreased anticancer activity. …”

Table_3_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.XLSX by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Image_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.TIF by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Table_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.docx by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Table_2_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.xlsx by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Transgenerational hormetic effects of sublethal dose of flupyradifurone on the green peach aphid, <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae) by Qiuling Tang (495407)

“…<i>persicae</i> with a 48 h LC₅₀ of 8.491 mg/L. Using the age-stage two-sex life table approach, we assessed the effects of LC₂₅ of flupyradifurone on adult <i>M</i>. …”

5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes by Hsueh-Yun Lee (141907)

“…<i>N</i>-Hydroxy-4-((5-(4-methoxybenzoyl)-1<i>H</i>-indol-1-yl)­methyl)­benzamide (<b>6</b>) has potent inhibitory selectivity against histone deacetylase 6 (HDAC6) with an IC₅₀ value of 3.92 nM. It decreases not only the level of phosphorylation of tau proteins but also the aggregation of tau proteins. …”

Native albumin antioxidant response to stress produced by short-wave UV light. by Rafael Medina-Navarro (253862)

“…At a low concentration, the human serum albumin (HSA) Cys34-SH groups are oxidized and the AC decreases. …”

Effects of Sediment Characteristics on the Toxicity of Chromium(III) and Chromium(VI) to the Amphipod, <i>Hyalella azteca</i> by John M. Besser (467734)

“…Waterborne Cr(VI) caused reduced survival of amphipods with a median lethal concentration (LC₅₀) of 40 μg/L. …”

Phylogenetic tree based on a partial sequence (482 bp) of 18S rRNA gene of <i>Theileria ovis</i> isolated in this study (bold letters) with other small ruminants <i>Theileria</i> s... by Muhammad Irfan (255476)

Data_Sheet_1_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.PDF by Michał Szopiński (6806870)

“…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …”

Data_Sheet_2_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.PDF by Michał Szopiński (6806870)

“…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …”

Table_1_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.DOCX by Michał Szopiński (6806870)

“…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …”

Table_2_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.DOCX by Michał Szopiński (6806870)

“…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …”

Data_Sheet_3_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.PDF by Michał Szopiński (6806870)

“…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …”

Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension by Wei-Hua Liu (4751559)

“…The effects of simvastatin were mediated by inhibition of RhoA/ROCK1. Simvastatin decreased RhoA/ROCK1 overexpression by inhibition of mevalonate, FPP, and GGPP synthesis.…”