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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
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5601
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5603
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa
Published 2023“…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”
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5604
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5605
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5606
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5607
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5608
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5609
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5610
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5611
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5612
<i>Bbs1</i><sup><i>M390R/M390R</i></sup> mice have decreased hippocampal proliferation.
Published 2021“…The Red Bar line represents 50μm. G.) Decreased proliferation in the dentate gyrus of P3 <i>Bbs1</i><sup><i>M390R/M390R</i></sup> mice. …”
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5613
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5614
DataSheet_1_SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.pdf
Published 2022“…In the presence of high APOBEC3G levels, however, increased LTR activity upon SRSF1 knockdown facilitated the overall replication, despite decreased vif mRNA levels. In contrast, SRSF1 overexpression significantly impaired HIV-1 post-integration steps including LTR transcription, alternative splice site usage, and virus particle production. …”
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5615
Patient data.
Published 2024“…</p><p>Results</p><p>On average, the time required to move through the obstacle course decreased by 17.0% after the training phase, the number of collisions decreased by 50.0%. …”
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5616
Reduction of the mean absolute error (MAE) in time for all participant on x-axis.
Published 2019“…<p>A similar effect is observed for y-axis. The MAE obtained using the standard regression (orange circles) decreased significantly when using symbolic regression. …”
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5617
Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in <i>Trypanosoma cruzi</i>
Published 2017“…Isotretinoin inhibited the polyamine transport, as well as other amino acid transporters from the same protein family (<i>Tc</i>AAAP), with calculated IC<sub>50</sub> values in the range of 4.6–10.3 μM. It also showed a strong inhibition of trypomastigote burst from infected cells, with calculated IC<sub>50</sub> of 130 nM (SI = 920) being significantly less effective on the epimastigote stage (IC<sub>50</sub> = 30.6 μM). …”
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5618
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5619
Effect of variable Mean Fluorescent Intensity (MFI) on the identification of nucleotides in the consensus output.
Published 2017“…Decreasing average MFI results in an overall reduction of correct nucleotides with an inverse increase in ambiguous nucleotides; seen as a shift in the 50% correct:unidentified ratio to a lower threshold. …”
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5620
Cell motility depends on a QSF secreted by cells.
Published 2011“…Applied flow is changed with exponential step (green line, vertical right axis). is first decreasing (corresponding to a state where QSF cell emission is overcoming QSF flow dilution), then increasing (corresponding to a state where QSF flow dilution is overcoming QSF cell emission). …”