The second-order rate-yield tradeoff demonstrated by decreasing the P/O ratio and and knocking out <i>gnd</i> (“Δ<i>gnd</i>”) in ME-model simulations. by Chuankai Cheng (6791417)

OPTN degrades GSK3β via activating LC3-mediated autophagy. by Xiao Chen Shi (8611887)

Contingency relation between IPI before and IPI after each pulse. by Laura N. Kloepper (8173881)

Flow chart for patients inclusion. by Haruka Imai (3703819)

“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”

The outcome measures in IPTW analysis. by Haruka Imai (3703819)

“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”

Locomotion and turning angle sizes of adult <i>D</i>. <i>melanogaster</i>, <i>D</i>. <i>simulans</i>, <i>D immigrans</i>, <i>D</i>. <i>subobscura</i> and <i>D pavani</i> in Petri d... by Jeannette Silva-López (16541854)

<i>F</i>. <i>oxysporum</i> f. sp. <i>albedinis</i> genome code for a large repertoire of secreted proteins. by Maryam Rafiqi (12647200)

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Homogeneous Electrocatalytic Reduction of CO₂ by a CrN₃O Complex: Electronic Coupling with a Redox-Active Terpyridine Fragment Favors Selectivity for CO by Amelia G. Reid (13983239)

“…Computational analyses indicate that, although the stoichiometry of both reactions is identical, changes in the observed rate law are the combined result of a decrease in the intrinsic ligand charge (L₃X vs L₂X₂) and an increase in the ligand redox activity, which result in increased electronic coupling between the doubly reduced tpy fragment of the ligand and the Cr^II center. …”

Number of bars of length greater than <i>ℓ</i> = 4000 in the barcodes obtained via the binary model (left) and the fuzzy binary model (right) as a function of <i>τ</i>. by Samir Chowdhury (5715338)

Complement evasion by <i>P</i>. <i>aeruginosa</i> is a multifactorial phenomenon. by Manon Janet-Maitre (14504859)

Triclosan Dioxygenase: A Novel Two-component Rieske Nonheme Iron Ring-hydroxylating Dioxygenase Initiates Triclosan Degradation by Yiran Yin (19144130)

“…The highest amino acid identity of TcsA and the large subunits of other dioxygenases in the same family was only 35.50%, indicating that TcsAB is a novel dioxygenase. …”

Plots of gene expression values for <i>SOX5</i>, <i>COL2A1</i>, <i>ELN</i>, <i>B2M</i>, <i>CASP8</i>, <i>CASP9</i>, and <i>IL1A</i> normalized to large ribosomal fraction, <i>P0</i... by Narihiko Hirano (11104945)

LDHA is increased in bleomycin-induced pulmonary fibrosis. by Jennifer L. Judge (5278415)

Water supply head entries, a raw measure of rat’s activity, show rapid increase at the time the lights were turned on at 06:00 but no change at the time the lights were turned off.... by Piotr Popik (292215)

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. by Sen-Mao Tien (12481273)

Effects of changes in anionic phospholipids on SAUR63 localization. by Punita Nagpal (185838)