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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
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6564
Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant <i>S. aureus</i> (MRSA) Infections by Targeting Diapop...
Published 2016“…In our previous work, diapophytoene desaturase (CrtN) was identified to be an attractive and drugable target for fighting pigmented <i>S. aureus</i> infections. In this research, we developed a series of effective benzocycloalkane-derived CrtN inhibitors with submicromolar IC<sub>50</sub>. …”
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6565
Sensitivity of mean population biomass and cumulative harvest to initial biomass to the rate of demographic change due to climate impacts.
Published 2025“…All parameters are at their default values (<a href="/article/info:doi/10.1371/journal.pclm.0000624#pclm.0000624.s002" target="_blank">S1 Table</a>); note that initial and final values of <i>r</i> and <i>K</i> differ in the decreasing versus increasing scenarios (<a href="/article/info:doi/10.1371/journal.pclm.0000624#pclm.0000624.s003" target="_blank">S2 Table</a>). …”
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6566
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6567
Inhibition of IL-6 Signaling Pathway by Curcumin in Uterine Decidual Cells
Published 2015“…To further understand whether NF-ҡB is involved in this inhibition, we examined the effect of curcumin on the expression of p50 and p65 subunits of NF-ҡB in decidual cells. …”
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6568
The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance <i>In Vitro</i> and <i>In Vivo</i> Derived from Human Breast MCF-7/ADR Cells
Published 2014“…Multidrug resistance reversal by 3-Bromopyruvate occurred through at least three approaches, namely, a decrease in the intracellular level of ATP and HK-II bioactivity, the inhibition of ATPase activity, and the slight decrease in P-glycoprotein expression in MCF-7/ADR cells.…”
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6569
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6570
Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome
Published 2020“…Surprisingly, in ALDH6A1-O/E cells, NO was decreased nearly 50% but ROS was increased at a similar level, while the former was restored by treatment with <i>S</i>-nitroso-<i>N</i>-acetyl-penicillamine. …”
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6571
Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger
Published 2016“…<div><p>Objective</p><p>Biomedical investment trends in 2015 show a huge decrease of investment in gastroenterology. …”
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6572
Density Functional Study on Compounds to Accelerate the Electron Capture Decay of <sup>7</sup>Be
Published 2021“…Thus, the decay can be accelerated by changing the chemical or physical conditions. A previous study reported a 1.1–1.5% reduction in the half-life of <sup>7</sup>Be encapsulated in C<sub>60</sub> compared with <sup>7</sup>Be metal. …”
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6573
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6574
PowerPoint Slides for: Urinary Periostin Excretion Predicts Renal Outcome in IgA Nephropathy
Published 2016“…Histologically, group 3 patients were correlated with severe interstitial fibrosis/tubular atrophy (p = 0.004), interstitial inflammation (p = 0.007), hyaline arteriolosclerosis (p = 0.001) and glomerular sclerosis (p < 0.001). A higher initial uPOSTN/Cr level was associated with a greater decline in eGFR during follow-up (p = 0.043 when initial eGFR ≥60; p = 0.025 when eGFR <60 ml/min/1.73 m2), and the renal outcomes with end-stage renal disease (ESRD; p = 0.003), ESRD and/or eGFR decrease of >30% (p = 0.033) and ESRD and/or eGFR decrease of >50% (p = 0.046) occurred significantly more in group 3. …”
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6580