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6701
A Method for Selectively Enriching Microbial DNA from Contaminating Vertebrate Host DNA
Published 2013“…We report enrichment of DNA samples from human saliva, human blood, a mock malaria-infected blood sample and a black molly fish. …”
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6702
Thermal stability and hydrophobicity of six fish αA-crystallins was correlated with physiological temperature.
Published 2012“…Sliding window of 15 with a step of one was used; midpoint mean is displayed.…”
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6703
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6704
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6705
A dynamin-based inhibitory peptide (DYN) blocks LTP and the reduction of A-type K<sup>+</sup> currents.
Published 2009“…<p>In these experiments we included DYN in the patch pipette to prevent clathrin mediated endocytosis <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006549#pone.0006549-Kim2" target="_blank">[12]</a>. …”
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6706
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6707
Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<...
Published 2022“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”
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6708
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6709
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6710
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6711
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6712
Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i>
Published 2023“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”
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6713
Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO
Published 2024“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”
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6714
Practical applications of the staining method.
Published 2016“…Our one-step staining method succeeded in verifying the decrease in MyHC2B fibers and the increase in MyHC2X fibers in the plantaris muscles of fish oil-fed rats compared with soybean oil-fed rats. …”
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6715
Simvastatin alters actin organization, cell morphology, and Rac1 activity in endothelial monolayers.
Published 2016“…Cell circularity, where a perfectly circular cell has a value of 1, decreases with increasing simvastatin concentration (n = 3, 50–54 cells per condition). …”
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6716
Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2
Published 2015“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”
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6717
Table_1_Guanidine acetic acid exhibited greater growth performance in younger (13–30 kg) than in older (30–50 kg) lambs under high-concentrate feedlotting pattern.docx
Published 2022“…In a brief, the results obtained in the present study suggested that GAA (UGAA and CGAA; 1 g/kg DM) could be applied to improve growth performance in younger (13–30 kg) instead of older (30–50 kg) lambs in high-concentrate feedlotting practice.…”
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6718
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6719
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6720