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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
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6801
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6802
(S)-(-)-blebbistatin O-benzoate reduces mast cell infiltration in AD-like lesions of NC/Nga mice.
Published 2024“…(S)-(-)-blebbistatin O-benzoate treatment significantly decreased mast cell numbers. Data represent mean ± SE, *<i>p</i> < 0.05 vs. vehicle.…”
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6803
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6804
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6805
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6806
MF induced EGFR interaction.
Published 2018“…C: The DEP FI decrease percentages in EGFR monomer solution with pretreatment of PD of a serial of concentration. …”
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6807
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6808
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6809
PAMAM-DEN<sup>CYS</sup> induces trafficking of ΔF508-CFTR to plasma membrane in CF cells.
Published 2017“…Data represent mean ± SEM of triplicate samples. (F) Immunofluorescence microscopy of HEK-293 cells transfected with ΔF508-CFTR and treated with PAMAM-DEN<sup>CYS</sup> (500μM, 12 hrs) show increased plasma membrane (PM, yellow arrows) trafficking of CFTR with decreased peri-nuclear aggresome-bodies (AB, red arrows) as compared to controls. …”
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6810
Quantitative structure–toxicity relationship models for predication of toxicity of ionic liquids toward leukemia rat cell line IPC-81 based on index of ideality of correlation
Published 2021“…The outliers and promoters of increase/decrease of logEC<sub>50</sub> are extracted and the mechanistic interpretation of effective descriptors for the model is also offered.Highlights</p><p>Global SMILES-based QSAR model was developed to predict the toxicity of ILs.…”
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6811
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6812
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6813
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6814
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6815
Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors
Published 2020“…The preliminary mechanistic studies indicated that compounds <b>6</b> and <b>43</b> possibly target the HAdV DNA replication process, while compounds <b>46</b> and <b>47</b> suppress later steps of HAdV life cycle. Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC<sub>50</sub> = 0.27 μM), significantly decreased cytotoxicity (CC<sub>50</sub> = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”
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6816
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6817
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6818
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6819
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6820